| Sequence 1: | NP_005952.2 | Gene: | MUC6 / 4588 | HGNCID: | 7517 | Length: | 2439 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_524060.2 | Gene: | Hml / 39529 | FlyBaseID: | FBgn0029167 | Length: | 3843 | Species: | Drosophila melanogaster |
| Alignment Length: | 1295 | Identity: | 376/1295 - (29%) |
|---|---|---|---|
| Similarity: | 559/1295 - (43%) | Gaps: | 201/1295 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Human 24 YTSPGLQRLKDSPQTAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRR 88
Human 89 GPDGS---ISRIIVELGASVVTVSEAIISVKD----IGVISLPYTSNGLQITPFGQSVRLVAKQL 146
Human 147 ELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHK-FAALQKLDDPG 210
Human 211 EICTFQD-------IPSTHVRQAQHA-RICTQLLT------LVAPECSVSKEPFVLSCQADVA-A 260
Human 261 APQPGPQNSSCATLSEYSRQCSMVGQPVRR-WRSPGLCSVGQCPANQVYQECGSACVKTCSN--- 321
Human 322 -PQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGR 385
Human 386 WVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSE-- 448
Human 449 --------TSLVAVVYLSRQ-DKIVISQDE---VVTNNGEAKWLP--YKTRNITVFRQTSTHLQM 499
Human 500 ATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA 564
Human 565 -GNC--PAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACN-Y 625
Human 626 EETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRAT- 689
Human 690 --ECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILE------GYKFILAEQSTVINGITCHC 746
Human 747 ING---------------------RLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQ 790
Human 791 MLATGVACVPTKCEPGCVCAEG-LYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRG 854
Human 855 RWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGN 919
Human 920 SGVTCSRAIKIFLGGLS----VVLADRNYTV-------------TGEEPHVQLGVTPGALSLVVD 967
Human 968 ISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWK 1032
Human 1033 ESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDSGGD 1097
Human 1098 CECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQD-------------------GHG 1143
Human 1144 EYQYTQEANCT--WHYQPCLCPSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVP---CMP 1198 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| MUC6 | NP_005952.2 | VWD | 40..192 | CDD:214566 | 38/158 (24%) |
| C8 | 228..297 | CDD:285899 | 15/77 (19%) | ||
| TIL | 302..357 | CDD:280072 | 20/58 (34%) | ||
| VWC_out | 359..>403 | CDD:214565 | 16/43 (37%) | ||
| VWD | 386..549 | CDD:214566 | 53/178 (30%) | ||
| C8 | 588..660 | CDD:285899 | 26/72 (36%) | ||
| TIL | 664..721 | CDD:280072 | 20/59 (34%) | ||
| TIL | 782..827 | CDD:280072 | 13/45 (29%) | ||
| VWC | 829..886 | CDD:302663 | 23/56 (41%) | ||
| VWD | 868..1017 | CDD:278521 | 52/165 (32%) | ||
| C8 | 1057..1127 | CDD:285899 | 33/69 (48%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1202..1455 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1471..1626 | ||||
| 1, truncated | 1561..1738 | ||||
| Approximate repeats | 1607..1953 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1642..1834 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1868..1983 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2033..2077 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2090..2196 | ||||
| PHA03255 | 2188..>2343 | CDD:165513 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2233..2278 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2323..2348 | ||||
| CT | 2351..2434 | CDD:214482 | |||
| Hml | NP_524060.2 | VWD | 485..636 | CDD:295339 | 37/154 (24%) |
| C8 | 680..754 | CDD:285899 | 15/76 (20%) | ||
| TIL | 758..811 | CDD:280072 | 20/58 (34%) | ||
| VWD | 840..1015 | CDD:214566 | 53/178 (30%) | ||
| C8 | 1054..1121 | CDD:214843 | 23/69 (33%) | ||
| TIL | 1131..1185 | CDD:280072 | 20/59 (34%) | ||
| TIL | 1245..1298 | CDD:280072 | 21/70 (30%) | ||
| VWD | 1327..1498 | CDD:214566 | 57/177 (32%) | ||
| C8 | 1535..1609 | CDD:214843 | 35/73 (48%) | ||
| Mucin2_WxxW | 1751..1837 | CDD:290069 | |||
| TIL | 1938..2005 | CDD:280072 | |||
| FA58C | 2089..2223 | CDD:238014 | |||
| FA58C | 2104..2225 | CDD:214572 | |||
| FA58C | <2299..2404 | CDD:214572 | |||
| FA58C | <2299..2403 | CDD:238014 | |||
| VWD | 2703..2858 | CDD:295339 | |||
| C8 | 2893..2970 | CDD:285899 | |||
| TIL | 2974..3030 | CDD:280072 | |||
| VWD | 3035..3198 | CDD:295339 | |||
| C8 | 3257..3313 | CDD:285899 | |||
| VWC | 3397..3451 | CDD:302663 | |||
| GHB_like | <3755..3813 | CDD:304424 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 97 | 1.000 | Domainoid score | I7243 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG1216 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D12226at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100854 | |
| Panther | 1 | 1.100 | - | - | O | PTHR11339 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 7 | 6.820 | |||||