DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MUC6 and muc5.1

DIOPT Version :9

Sequence 1:	NP_005952.2	Gene:	MUC6 / 4588	HGNCID:	7517	Length:	2439	Species:	Homo sapiens
Sequence 2:	XP_021326297.1	Gene:	muc5.1 / 100148804	ZFINID:	ZDB-GENE-120822-1	Length:	5282	Species:	Danio rerio

Alignment Length:	3415	Identity:	933/3415 - (27%)
Similarity:	1273/3415 - (37%)	Gaps:	1161/3415 - (33%)

- Green bases have known domain annotations that are detailed below.

Human     1 MVQRWLLLSCCGALLSAGLANTSYTSPGLQRLKDSPQTA---------------------PDKGQ 44
            |.|.|:|.   ...|.|||.:......|..|..::|.|.                     ||...
Zfish    11 MPQMWMLR---WVFLLAGLQSIQAGFMGDYRDMENPMTPMWPTTPAISMTSVPVITVEPNPDHRS 72

Human    45 --CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGP-DGSI--SRIIVELGAS 104
              |||||..||.|||.|.:....||||:.|..|..|...|::|::|.. :|||  |.::::|..:
Zfish    73 TICSTWGNFHFKTFDGHFFQLPDTCNYVLAVMCDAASSDFNIQMQRETVNGSISFSTVLIKLDGT 137

Human   105 VVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYM 169
            |:.|:::.|::.: ..:::|...||::|.....|.::..|.   .:.|.|..|:.|.:.:..||.
Zfish   138 VIKVTDSDITMGE-ETVTVPTYKNGIKIEGSPTSFKISNKH---GVTVFWEEDNSLSIELPEKYQ 198

Human   170 GQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPSTHV--RQAQHARIC 232
            ||.|||||:|:|.:.:: :::.|        .|..|:....|||....:|||..  ..::.|..|
Zfish   199 GQTCGLCGDFNGNLADD-ITDNG--------PATWKVSISTEICEEVTLPSTGPCDELSEQASFC 254

Human   233 TQLLTLVAPECS-----VSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWR 292
            .:.  |::|..|     :....|..:|.:|:...  .|..:..|.||:|.||||:..|.....||
Zfish   255 EEY--LISPGFSGCYDVMDMRIFQKACVSDLCQC--YGNHDCLCNTLTEISRQCTHAGGQPGTWR 315

Human   293 SPGLCSVGQCPANQVYQECGSACVKTCSNPQHS--CSSSCTFGCFCPEGTVLNDLSNNHTCVPVT 355
            :..||. ..||.|..|.|||..|..|||.|..:  |:..|..|||||||||.:|:..: .||||.
Zfish   316 TEQLCP-KTCPLNLQYLECGGPCRNTCSAPTANLMCTDHCVDGCFCPEGTVEDDIGQS-GCVPVN 378

Human   356 QCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCT 420
            :||||..|.:|..||....||::|.|..|.|.||...|||.||:.|||.|||||.:.:.|.|.|.
Zfish   379 ECPCVHDGTVYKSGESYQQACKSCTCDAGHWTCTYLDCPGTCSVVGGSHVTTFDGKSFTFSGNCD 443

Human   421 YILLQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQD-EVVTNNGEAKWLPYKT 484
            |||.:. ....|.|::....|...|.::|.|.:|..:.....|..|.. :|..||..:|.||:..
Zfish   444 YILTKH-SADSDFAVVGNLAKCEASRTDTCLHSVTLVISGTTISFSSSGDVTLNNINSKELPFSI 507

Human   485 RNITVFRQTSTHLQM-ATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSM 548
            ..:::|:.:|:.:.: .||..||  :||.|:.|.|:....:.:|:..|||||:|...||||.|..
Zfish   508 GPVSIFQPSSSFIIVDLTSVRLE--IQLAPVMQLYIVASTEEKGKMTGLCGNYNDVQTDDFKTES 570

Human   549 GIAEGTASLFVDSWRAGNCPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAP 613
            ||.|||.:.||:.|:. |||.......:|||::...:..|:..||.|......|..||:.:.|..
Zfish   571 GIIEGTPTSFVNFWKQ-NCPDLEITFDNPCSLNMDTEKLAKDWCSRLTNPNGTFSECHSEICPEM 634

Human   614 FYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACE 678
            :|:||||..|...:....||||:..|.|||:.||::|..|..: :.|...|..|...||...:|.
Zfish   635 YYQRCVYDTCKCSDIRKCICAAVSTYAHACAARGIILHDWMDT-EPCESECPENMKHSYEVTSCG 698

Human   679 RTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVIN--G 741
            .||.|||.:...|..|..||.||.|.:|||||::|:||....|||.   |...:.:.|...|  |
Zfish   699 STCRSLSGQENTCQGSFTPVHGCVCSEGTYLNEEGKCVHAGMCPCY---YGNQVIQPSAEFNKEG 760

Human   742 ITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPG 806
            ..|.|.||:|.|...     ..|.||.||..||...|.  |..|..||...... .||.|.|..|
Zfish   761 AKCTCNNGKLDCSSH-----EDCVAPMTFFKCSHPGEK--GTECQRTCDKQDPN-NCVSTGCVSG 817

Human   807 CVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLY 871
            |:|.|||..:..|.||..|.|||..:||:...|.::..||.||:|:.|.|.|.|.. |..|||:|
Zfish   818 CMCPEGLLADGKGGCVMRENCPCTHNGVTSSPGDQVQQDCNTCTCTNGMWICTQKA-CYGTCTIY 881

Human   872 GEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLS 936
            ||||..||||.|:.|.|:||:.||.|.|..|.| |:|:::|||:.|..:...||::|.:|.|...
Zfish   882 GEGHFRTFDGNRYSFHGDCEHTLAHDYCDGNPS-PSFRLVTENIPCATANSICSKSINLFFGRYE 945

Human   937 VVLA--DRNYTVTGEEPHVQLGVTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLC 999
            ::|:  |....|.|.....:..:..|.:.:|::|.  |..|  |||:...:::|::....:..:|
Zfish   946 MILSEDDGVKVVEGNGTEYKYQINYGGIYVVIEIE--GLLN--LIWDEKTSVMIQLHPKLKGNVC 1006

Human  1000 GLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVI 1064
            ||||||:||..:||...:..|.:...|..||||....|.||:.|..||..:..|.|||.::|.:|
Zfish  1007 GLCGNFDGNANNDFMKHNGEVVTDPEEFGNSWKVDSNCPDVTNVMHPCEAHPHRNSWAIKQCRII 1071

Human  1065 NSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPI 1129
            .|..|..|||.|...|||:|||||.|.|||||||:|||.||.|||..|..:|.||.||||.|||:
Zfish  1072 TSPVFTDCHSLVDSGPYYDACVRDTCACDSGGDCDCLCTAVGAYAAECRKRGACVAWRTPHFCPL 1136

Human  1130 YCGFYNTHTQDGHGEYQYTQEANCTWHYQPC---------------------------LCPSQ-- 1165
            :|.:||     ..||        |.|||:.|                           .|||:
Zfish  1137 FCDYYN-----APGE--------CQWHYKTCGSTCMKTCRNPLGTCSDQIPPLEGCFLQCPSERP 1188

Human  1166 ---PQSVPGSNIEGCYNCSQDEYFDHE--------------EGVC----------------VPCM 1197
               .:::.....|||.:|    ::|.:              .|.|                ..|:
Zfish  1189 YLREETMKCVTEEGCKDC----FYDGKVYPRGSVIYNTTDGSGACFSAKCDYNGEIIREIKTDCI 1249

Human  1198 PPTTP----QPPTTPQLPTTGSRP----TQVWPMTGTSTTIG----LLSSTGPSPSSNHTPASPT 1250
            ..|||    .||:|....|:...|    :.:.|.|||||...    :.:::..||::..:.::.|
Zfish  1250 ITTTPFTFSTPPSTTVTITSTETPSTITSTITPTTGTSTPTSTETPITTTSITSPTTETSTSTST 1314

Human  1251 QTPLLPATLTS---SKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAST 1312
            :||..||:.||   ...|::|.|.|...|:.....|....||:|  .|...|:.|.|||..|::|
Zfish  1315 ETPPTPASTTSPTTETSTSTSTETPSTITSTVTPTTETSTPTST--ETVPTPSTTTATTTPTSTT 1377

Human  1313 A---------------------------------------------------------------- 1313
            .
Zfish  1378 TPICVPRCEWSDWIDSNKPNTEPEGFETESIPLLWNSRRITCQSPEEVECRAVNYPQKTLEDLGQ 1442

Human  1314 ----------------------------------------SPATTSTAQSTTRTTMTLPTPATSG 1338
                                                    |..||||..::|.|    |:..||.
Zfish  1443 TVYCNTSFGLSCSNEDNAEGLPPICYNYEIRVYCCKENCPSDTTTSTPSTSTET----PSTTTST 1503

Human  1339 TSPTLPKS--TNQELPGT---TATQTTGPR--------PTPASTTGPTTPQPGQPTRPTATET-- 1388
            ||||...|  |:.|.|.|   |.|.|||..        |||||||.|||    :.:.||:|||
Zfish  1504 TSPTTETSTPTSTETPSTITSTVTPTTGTSTPTSTETPPTPASTTSPTT----ETSTPTSTETPS 1564

Human  1389 TQTRTTTEYTTPQTPHTTHSPPTAGSPV-PSTGPVTATSFHATTTYPTPSHPETTLPTH------ 1446
            |...||:..|...||.:|.:|.|..|.| |:|...|.||   |.|.||||....|.||.
Zfish  1565 TTASTTSPTTETSTPTSTETPSTITSTVTPTTETSTPTS---TETVPTPSTTTATTPTSTTTPIC 1626

Human  1447 ----------------------------------------------------------------- 1446

Zfish  1627 VPRCEWSDWIDSNKPNTEPEGFETESIPLLWNSKRITCQSPEEVECRAVNYPQKTLEDLGQTVYC 1691

Human  1447 ----------------VPPF------------------------STSLVTPSTHT----VITPTH 1467
                            :||.                        |||..||||.:    .:|||.
Zfish  1692 NTSFGLSCSNEDNAEGLPPICYNYEIRVYCCKENCPSDTTTSTPSTSTETPSTTSPTTETLTPTS 1756

Human  1468 AQMATSASNHSAP-TGTIPPPTTLKATGSTHTAPPITPTTSGTS-QAHSSFSTNKTPTSLHSHTS 1530
            .:..::.::...| |||:.|.:|...:.:..|..|.|.|::.|| :..|:.::..:||:..|..:
Zfish  1757 TETPSTITSTVTPTTGTLTPTSTETPSTTASTTSPTTETSTPTSTETPSTTASTTSPTTETSTPT 1821

Human  1531 STHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATS 1595
            ||..|..|.::|:..|...|.|.|.||...|::.|      |.|..|.||.:....:....|||:
Zfish  1822 STETPSTTASTTSPTTETLTPTSTETPSTITSTVT------PTTETSTPTSTETVPTPSTTTATT 1880

Human  1596 FKTTTTYP-----------------------------------------TP--------SHPQTT 1611
            ..|:||.|                                         :|        ::||.|
Zfish  1881 TPTSTTTPICVPRCEWSDWIDSNKPNTEPEGFETESIPLLWNSRRITCQSPEEVECRAVNYPQKT 1945

Human  1612 L--------------------------------------------PTHVPPF--STSLVTPSTHT 1630
            |                                            |:...|.  |||..||||.|
Zfish  1946 LEDLGQTVYCNTSFGLSCSNEDNAEGLPPICYNYEIRVYCCKENCPSDTTPSTPSTSTETPSTTT 2010

Human  1631 VIT--PTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQ-----ALSSLNTA 1688
            ..|  .|.....||....|..|.||.|.|......||.|.||...|||.|::     :..:.:|.
Zfish  2011 STTSPTTETSTPTSTETPSTITFTITPTTGTSTPTSTETPPTPASTTSPTTETSTPTSTETPSTT 2075

Human  1689 KTSTSLHSHTSSTHHAEATSTSTTNITP-----NPTSTGTPPMTVTTSGTSQSRS---------- 1738
            .::||..:.||:....|..||.|:.:||     .||||.|.|...||:.|:...|
Zfish  2076 ASTTSPTTETSTPTSTETPSTITSTVTPTTETSTPTSTETVPTPSTTTATTTPTSTTTPICVPRC 2140

Human  1739 ---------------------------------------------------------------SF 1740
                                                                           ||
Zfish  2141 EWSDWIDSNKPNTEPEGFETESIPLLWNSRRITCQSPEEVECRAVNYPQKTLEDLGQTVYCNTSF 2205

Human  1741 -------------------------------------STAKTSTSLHSHTSSTHHPEV-TSTSTT 1767
                                                 ||..|||...|.|:||..|.. |||.|:
Zfish  2206 GLSCSNEDNAEGLPPICYNYEIRVYCCKENCPSDTTPSTPSTSTETPSTTTSTTSPTTETSTPTS 2270

Human  1768 SITPNHTSTGTRTPVAHTTSATSSRL-PTPFTTHSPPTGT-TPISSTGPVTATSFQTTT------ 1824
            :.||: |.|.|.||...|::.||:.. |||.:|.||.|.| ||.|:..|.|.||..|.|
Zfish  2271 TETPS-TITFTITPTTGTSTPTSTETPPTPASTTSPTTETSTPTSTETPSTITSTVTATSETLTP 2334

Human  1825 ----TYPTPS--------HPHTTLPTHVP------------------------------------ 1841
                |.||||        ...||.|..||
Zfish  2335 TSTETVPTPSTTTATTATPTSTTTPICVPRCEWSDWIDSNKPNTEPEGFETESIPLLWNTKRITC 2399

Human  1842 -----------------------------SF---------------------------------S 1844
                                         ||                                 .
Zfish  2400 QSPEEVECRAVNYPQKTLEDLGQTVYCNTSFGLSCSNEDNAEGLPPICYNYEIRVYCCKDNCPSD 2464

Human  1845 TSLVTPSTHTVIIPTHTQMATSASIH-SMPTGTIPPPT-TIKATGSTHTAPPM---TPTTSGTSQ 1904
            |:..||||.|. .|:.|...||.:.. |.||.|..|.| |...|.:|.|:.|.   ||.|:.:..
Zfish  2465 TTTSTPSTSTE-TPSTTASTTSPTTETSTPTSTETPSTITSTVTPTTGTSTPTSTETPITTTSIT 2528

Human  1905 SPSSFSTAKTSTSLPYHTSSTHHPEV---TPTSTTNITPKHTSTGTRTPVAHT-TSASSSRLPTP 1965
            ||::.::..|||..|..|:||..|..   |||||.  ||. |.|.|.||...| |..|:..:|||
Zfish  2529 SPTTETSTPTSTETPSTTASTTSPTTETSTPTSTE--TPS-TITSTVTPTTETLTPTSTETVPTP 2590

Human  1966 FTTHSPPTGSSPFSSTGPMTA-------------------------------------------- 1986
            .||.:..|   |.|:|.|:..
Zfish  2591 STTTATTT---PTSTTTPICVPRCEWSDWIDSNKPNTEPEGFETESIPLLWNSKRITCQSPEEVE 2652

Human  1987 ---------------------TSF---------------------------------QTTTTYP- 1996
                                 |||                                 .|||:.|
Zfish  2653 CRAVNYPQKTLEDLGQTVYCNTSFGLSCSNEDNAEGLPPICYNYEIRVYCCKDNCPSDTTTSTPS 2717

Human  1997 ----TPS-HPQTTLPTHVPPFSTSLVTPS--THTVIITTHTQMATSASIHSTPTGTVPPPTTLKA 2054
                ||| ...||.||......||..|||  |.||..||.|...||....||.|.||.|.|....
Zfish  2718 TSTETPSTTASTTSPTTETSTPTSTETPSTITSTVTPTTGTLTPTSTETPSTITSTVTPTTETST 2782

Human  2055 TGSTHTAPPMTVTTSGTSQTHSSFSTATAS-------SSFISSSS----------------W--- 2093
            ..||.|.|..:.||:.|:.|    ||.|..       |.:|.|:.                |
Zfish  2783 PTSTETVPTPSTTTATTTPT----STTTPICVPRCEWSDWIDSNKPNTEPEGFETESIPLLWNSR 2843

Human  2094 ----------------LPQ------------------------NSSSRPP--------------- 2103
                            .||                        |:...||
Zfish  2844 RITCQSPEEVECRAVNYPQKTLEDLGQTVYCNTSFGLSCSNEDNAEGLPPICYNYEIRVYCCKEN 2908

Human  2104 -SSPITTQLPHLSSAT--TPVSTTNQLSSSFSP-SPSAPSTVSSYV--------PSSHSSP---- 2152
             .|..||..|..|:.|  |..|||:..:.:.:| |...|||::|.|        |:|..:|
Zfish  2909 CPSDTTTSTPSTSTETPSTTTSTTSPTTETSTPTSTETPSTITSTVTPTTGTSTPTSTETPPTPA 2973

Human  2153 QTSSPS--VGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSS-----------PAA 2204
            .|:||:  ..||:|..:.|..::|.|..:.:|.||...|.|...|.:.|::           |..
Zfish  2974 STTSPTTETSTSTSTETPPTPASTTSPTTETSTSTSTETPSTITSTVTPTTETSTPTSTETVPTP 3038

Human  2205 STTIRATLPHTISSP-------------------------------------------------- 2219
            |||...|.|.:.::|
Zfish  3039 STTTATTTPTSTTTPICVPRCEWSDWIDSNKPNTEPEGFETESIPLLWNSRRITCQSPEEVECRA 3103

Human  2220 --------------------FTLS--------ALLPI---------------------------- 2228
                                |.||        .|.||
Zfish  3104 VNYPQKTLEDLGQTVYCNTSFGLSCSNEDNAEGLPPICYNYEIRVYCCKENCPSDTTTSTPSTST 3168

Human  2229 -----STVTVSP-----TPSSHLASSTIAFPSTPRTTASTHTA------PAFSSQSTTSRSTSLT 2277
                 :|.|.||     ||:|....|||....||.|..||.|:      ||.::..||..|||.:
Zfish  3169 ETPSTTTSTTSPTTETSTPTSTETPSTITSTVTPTTGTSTPTSTETPPTPASTTSPTTETSTSTS 3233

Human  2278 TRVPTSGFVSLTSGVTGIPTSPV-TNLTTRHPG---PTLSPTTRFLTSSLTAHGSTPASAPVSSL 2338
            |..|.      |...|..||:.. |:.:|..|.   .|::|||.  ||:.|:..:.|..:..::.
Zfish  3234 TETPP------TPASTTSPTTETSTSTSTETPSTITSTVTPTTE--TSTPTSTETVPTPSTTTAT 3290

Human  2339 GTPTPTSPGVCSVREQQEEITFKGCMANVTVTRCE 2373
            .|||.|:..:|                   |.|||
Zfish  3291 TTPTSTTTPIC-------------------VPRCE 3306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MUC6	NP_005952.2	VWD	40..192	CDD:214566	52/156 (33%)
		C8	228..297	CDD:285899	20/73 (27%)
		TIL	302..357	CDD:280072	28/56 (50%)
		VWC_out	359..>403	CDD:214565	20/43 (47%)
		VWD	386..549	CDD:214566	60/164 (37%)
		C8	588..660	CDD:285899	26/71 (37%)
		TIL	664..721	CDD:280072	25/56 (45%)
		TIL	782..827	CDD:280072	18/44 (41%)
		VWC	829..886	CDD:302663	27/56 (48%)
		VWD	868..1017	CDD:278521	57/150 (38%)
		C8	1057..1127	CDD:285899	41/69 (59%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1202..1455		107/498 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1471..1626		51/251 (20%)
		1, truncated	1561..1738		68/283 (24%)
		Approximate repeats	1607..1953		155/640 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1642..1834		85/332 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1868..1983		48/123 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2033..2077		17/43 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2090..2196		41/197 (21%)
		PHA03255	2188..>2343	CDD:165513	59/291 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2233..2278		21/55 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2323..2348		6/24 (25%)
		CT	2351..2434	CDD:214482	4/23 (17%)
muc5.1	XP_021326297.1	VWD	72..217	CDD:214566	50/149 (34%)
		C8	263..320	CDD:312319	16/58 (28%)
		TIL	324..380	CDD:307783	28/56 (50%)
		VWD	420..571	CDD:306577	54/153 (35%)
		C8	606..680	CDD:214843	26/74 (35%)
		Pacifastin_I	848..>874	CDD:253170	10/26 (38%)
		VWD	867..1025	CDD:214566	62/163 (38%)
		C8	1063..1135	CDD:214843	43/71 (61%)
		Mucin2_WxxW	1386..1476	CDD:315900	0/89 (0%)
		Mucin2_WxxW	1631..1721	CDD:315900	2/89 (2%)
		Mucin2_WxxW	1895..1985	CDD:315900	5/89 (6%)
		Mucin2_WxxW	2141..2231	CDD:315900	2/89 (2%)
		Mucin2_WxxW	2366..2456	CDD:315900	2/89 (2%)
		Mucin2_WxxW	2612..2702	CDD:315900	3/89 (3%)
		Mucin2_WxxW	2814..2904	CDD:315900	9/89 (10%)
		Mucin2_WxxW	3060..3150	CDD:315900	6/89 (7%)
		Mucin2_WxxW	3306..3396	CDD:315900	1/1 (100%)
		Mucin2_WxxW	3552..3642	CDD:315900
		Mucin2_WxxW	3798..3888	CDD:315900
		VWD	4616..4779	CDD:214566
		C8	4818..4880	CDD:312319
		CT	5198..5274	CDD:214482
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D12226at2759
OrthoFinder	1	1.000	-	-		FOG0004663
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100854
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.720