DRSC/TRiP Functional Genomics Resources

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Protein Alignment ImpE1 and Lrp3

DIOPT Version :9

Sequence 1:NP_001261577.1 Gene:ImpE1 / 45879 FlyBaseID:FBgn0001253 Length:1616 Species:Drosophila melanogaster
Sequence 2:XP_038948896.1 Gene:Lrp3 / 89787 RGDID:619729 Length:810 Species:Rattus norvegicus


Alignment Length:451 Identity:98/451 - (21%)
Similarity:118/451 - (26%) Gaps:230/451 - (50%)


- Green bases have known domain annotations that are detailed below.


  Fly  1304 LMEPAAPVVTTLMPLMTADEPTPEP--VSPAAIPSASLAAIKPGTELRKRVDLGL--EAVSLGLA 1364
            |:.||||             |..|.  :..:|||.|.::|       |..|.:..  :|.|.|.|
  Rat   105 LLGPAAP-------------PRQEAFRLCGSAIPPAFISA-------RDHVWIFFHSDASSSGQA 149

  Fly  1365 ----------------CSSDR-------------QCQLADPHTVCNRRGVCDCAAGEEGSQCSA- 1399
                            |.:|.             ||.:.|           :|..|.:...||| 
  Rat   150 QGFRLSYIRGKLGQASCQTDEFRCDNGKCLPGPWQCNMVD-----------ECGDGSDEGNCSAP 203

  Fly  1400 --ERTG--CSPGTFQCRSSGV----CISWFFVCDGRADCNDASDE-------------------- 1436
              |..|  |..|||.|  ||.    |:.....|||..||.|.|||                    
  Rat   204 ASEPPGSLCPGGTFPC--SGARSTRCLPVERRCDGTQDCGDGSDEAGCPDLACGRRLGSFYGSFA 266

  Fly  1437 --------------ECT---------------------------------HNARLNQTCPTES-- 1452
                          .||                                 ...||.||....|  
  Rat   267 SPDLFGAARGPSDLHCTWLVDTQDPRRVLLQLELRLGYDDYVQVYEGLGERGDRLLQTLSYRSNH 331

  Fly  1453 -----------------FRCQRSGR----------------------------------CISRAA 1466
                             .|.:.:|.                                  |.|...
  Rat   332 RPVSLEAAQGRLTVAYHARARSAGHGFNATYQVKGYCLPWEQPCGSSSEGDDGSTGEQGCFSEPQ 396

  Fly  1467 LCDGRRQCPHGEDELGCDGSVKGGNACPEHTFRC--GSGECLPEYEYCNAIVSCKDGSDEPPHLC 1529
            .|||...|..|.||.||.       |||...:.|  |||.|....:.||...||.||:||..  |
  Rat   397 RCDGWWHCASGRDEQGCP-------ACPPDQYPCEGGSGLCYAPADRCNNQKSCPDGADEKN--C 452

  Fly  1530 GSRALPNLFMRLIEAGGLLGGGRREADAYCPHRCSNGLCRSTAIVCSGRDGCGDGTDEQTC 1590
            .| ..|..|                       .|...||......|.|::.|.||:||..|
  Rat   453 FS-CQPGTF-----------------------HCGTNLCIFETWRCDGQEDCQDGSDEHGC 489

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ImpE1NP_001261577.1 EB 75..131 CDD:279949
LDLa 1404..1437 CDD:238060 17/70 (24%)
LDLa 1448..1483 CDD:238060 12/87 (14%)
LDLa 1493..1524 CDD:238060 13/32 (41%)
LDLa 1561..1590 CDD:238060 10/28 (36%)
Lrp3XP_038948896.1 CUB 43..156 CDD:238001 18/70 (26%)
LDLa 166..200 CDD:238060 7/44 (16%)
LDLa 212..249 CDD:238060 17/38 (45%)
CUB 254..364 CDD:238001 9/109 (8%)
LDLa 416..452 CDD:238060 15/37 (41%)
LDLa 455..489 CDD:238060 12/56 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1215
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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