DRSC/TRiP Functional Genomics Resources

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Protein Alignment ImpE1 and Lrp10

DIOPT Version :9

Sequence 1:NP_001261577.1 Gene:ImpE1 / 45879 FlyBaseID:FBgn0001253 Length:1616 Species:Drosophila melanogaster
Sequence 2:NP_075369.2 Gene:Lrp10 / 65107 MGIID:1929480 Length:713 Species:Mus musculus


Alignment Length:336 Identity:81/336 - (24%)
Similarity:108/336 - (32%) Gaps:108/336 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly  1360 SLGLACSSDRQ-CQLADPHTVCNRRGVCDCAAGEEGSQCSAERTGCSPGTFQCRSSG-----VCI 1418
            :||..|.|:.| |.           |..|||.|.:...|    .||.||.|.|.::|     .|.
Mouse   327 NLGERCYSEAQRCD-----------GSWDCADGTDEEGC----PGCPPGHFPCGAAGTPGATACY 376

  Fly  1419 SWFFVCDGRADCNDASDE-ECTHNARLNQTCPTESFRCQRSGRCISRAALCDGRRQCPHGEDELG 1482
            .....|:.:..|.|.:|| .|.|       |...:||| |..:|:....:|||:..|..|.||..
Mouse   377 LPADRCNYQTFCADGADERRCRH-------CQPGNFRC-RDEKCVYETWVCDGQPDCTDGSDEWD 433

  Fly  1483 CD-------------GS--------VKGGNACPEHTFRCG----------------SGECLPEYE 1510
            |.             ||        :..|..|..:..|..                ..:..|.|.
Mouse   434 CSYALPRKVITAAVIGSLVCGLLLVIALGCTCKLYAIRTQEYSIFAPLSRMEAEIVQQQAPPSYG 498

  Fly  1511 YC---NAIVSCKDGSDEPPH----LCGSRALPNLFMRLIEAGGLLGGGRRE-------------- 1554
            ..   .||...:|...|.|:    |...|:|..:..:.:..||..||.||:              
Mouse   499 QLIAQGAIPPVEDFPTENPNDNSVLGNLRSLLQILRQDMTPGGTSGGRRRQRGRSIRRLVRRLRR 563

  Fly  1555 ----------------ADAYCPHRCSNGLCRSTAIVCSGRDGCGDGTD-EQTCSV-CRCPAPTAA 1601
                            .....|...|..|..||...|.|  |...|.| ||...: .:.|.||.:
Mouse   564 WGLLPRTNTPARAPETRSQVTPSVPSEALDDSTGQACEG--GAVGGQDGEQAPPLPIKTPIPTPS 626

  Fly  1602 SLPAFLARQRP 1612
            :|||......|
Mouse   627 TLPALATVSEP 637

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ImpE1NP_001261577.1 EB 75..131 CDD:279949
LDLa 1404..1437 CDD:238060 12/38 (32%)
LDLa 1448..1483 CDD:238060 13/34 (38%)
LDLa 1493..1524 CDD:238060 7/49 (14%)
LDLa 1561..1590 CDD:238060 11/29 (38%)
Lrp10NP_075369.2 CUB 35..135 CDD:238001
LDLa 141..175 CDD:238060
CUB 193..303 CDD:238001
LDLa <331..354 CDD:238060 9/33 (27%)
LDLa 400..434 CDD:238060 13/34 (38%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 566..636 18/71 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1215
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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