DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ImpE1 and cue

DIOPT Version :9

Sequence 1:	NP_001261577.1	Gene:	ImpE1 / 45879	FlyBaseID:	FBgn0001253	Length:	1616	Species:	Drosophila melanogaster
Sequence 2:	NP_612113.2	Gene:	cue / 38174	FlyBaseID:	FBgn0011204	Length:	644	Species:	Drosophila melanogaster

Alignment Length:	165	Identity:	39/165 - (23%)
Similarity:	52/165 - (31%)	Gaps:	65/165 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 VVDASRSLEL------------GDKCQHDMD---------CTDFIKGSSCSALGYCECAPYFVQL 82
            |.:.||..|:            .::|.:|.:         |....|||.|...   ||..|.|.
  Fly   348 VDEQSRKFEIRSLLDQKIKVLEDERCMNDGEYRAATDLCICPTGFKGSRCEIR---ECHNYCVH- 408

  Fly    83 DSKRCLSSQLLGGDCQLSEQCSMKVANSSCLEGACRCVEGFLQFR--KHTCLGPAHPGAVCYSHA 145
                        |.||:||....|          |.|..||...|  ...|.|      :|.:..
  Fly   409 ------------GTCQMSELAYPK----------CYCQPGFKGERCELSVCSG------LCLNGG 445

  Fly   146 HCQMFDTRTHCDFLIPNLFGRCQCTSPAKMVGGLC 180
            ||::.......    |:    |:|  |||..|..|
  Fly   446 HCRVSKDENEA----PS----CEC--PAKFGGARC 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ImpE1	NP_001261577.1	EB	75..131	CDD:279949	14/57 (25%)
		LDLa	1404..1437	CDD:238060
		LDLa	1448..1483	CDD:238060
		LDLa	1493..1524	CDD:238060
		LDLa	1561..1590	CDD:238060
cue	NP_612113.2	LY	101..141	CDD:214531
		Ldl_recept_b	167..208	CDD:278487
		LY	193..237	CDD:214531
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1215
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900