DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ImpE1 and CG11674

DIOPT Version :9

Sequence 1:	NP_001261577.1	Gene:	ImpE1 / 45879	FlyBaseID:	FBgn0001253	Length:	1616	Species:	Drosophila melanogaster
Sequence 2:	NP_572948.1	Gene:	CG11674 / 32374	FlyBaseID:	FBgn0030551	Length:	344	Species:	Drosophila melanogaster

Alignment Length:	259	Identity:	63/259 - (24%)
Similarity:	84/259 - (32%)	Gaps:	98/259 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly  1361 LGLACSSDRQC------QLADPHTVCNRRGVCDCAAGEEGSQCSAERTGCSP------------G 1407
            |.|:||||.||      :..|...:|..||             |.||..|:|            |
  Fly    25 LELSCSSDAQCAQFERGRCVDMACICTARG-------------SGERVPCTPLEERLKLTNIIGG 76

  Fly  1408 TFQC-RSSGVCISWFFVC---------DGRADCNDASDEECTHNARLNQTCPTESFRCQRSGR-- 1460
            ...| ..:.:|.:.:..|         |.|..|..|.       ..:..:|..:. :|||:.|
  Fly    77 ACPCPMPNAICHTRWQQCHCSEGHVSSDDRRRCLPAV-------VPVGGSCEFQQ-QCQRADRFS 133

  Fly  1461 -CISRAALC-------DGR------RQCPHGEDELGCDGSVKGGNACPEHTFRCGSGECLPEYEY 1511
             ||....||       :||      ..|...:|...|     |.:.|...|.|||   |...:.:
  Fly   134 SCIGNQCLCLNQFEFHEGRCLSVLQSSCLEDKDCGSC-----GASICLTKTKRCG---CSKNFVH 190

  Fly  1512 CNAIVSCKDGS---DEPPHLCGSRALPNLFMRLIEAGGLLGGGRREADAYC-PHRCSNGLCRST 1571
            .:.:..|..||   |...|  .|....||                .||..| .|.|   :||||
  Fly   191 NHNMTKCIKGSAYGDTCEH--SSPCKLNL----------------GADGRCLDHLC---VCRST 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ImpE1	NP_001261577.1	EB	75..131	CDD:279949
		LDLa	1404..1437	CDD:238060	10/54 (19%)
		LDLa	1448..1483	CDD:238060	13/50 (26%)
		LDLa	1493..1524	CDD:238060	9/33 (27%)
		LDLa	1561..1590	CDD:238060	6/11 (55%)
CG11674	NP_572948.1	EB	96..153	CDD:279949	14/64 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR39069
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010