Protein Alignment ImpE1 and yl

DIOPT Version :10

• Sequence 1: NP_524849.2
• Gene: ImpE1 / 45879
• FlyBaseID: FBgn0001253
• Length: 1616
• Species: Drosophila melanogaster
• Sequence 2: NP_996433.1
• Gene: yl / 32367
• FlyBaseID: FBgn0004649
• Length: 1984
• Species: Drosophila melanogaster
• Alignment Length: 693
• Identity: 153/693 - (22%)
• Similarity: 252/693 - (36%)
• Gaps: 171/693 - (24%)

  Fly   974 EDHKLTKPEMDYTSVEHLQELSRP------EETTAA---IEAEESDSRESTLAPE----APDAPI 1025
            :||::...:....:|.......:|      |..|.:   :.||......|...|:    |||...
  Fly   635 KDHRILAKDRTIYAVHIYHPAKQPNSPHGCENATCSHLCLLAEPEIGGHSCACPDGMRLAPDHRR 699

  Fly  1026 AIVSEER------------DPEHDPQNFHE-----------SESIADILSDLMLEADSTVPPV-P 1066
            .::.|:|            :.||.....|:           :|.:.:.::..::.||:....: .
  Fly   700 CMLMEKRQRLFIGLGQVLLEIEHTAFGRHQVSKSYTLPCLINEMVYNRINGSLIIADNDQRLILE 764

  Fly  1067 FGQQPAQTVPMVEANSENEEEQAHEAISDLQAEADETQEHAEQVQPVNEPGTAIPELFAEAAKDE 1131
            |..:..::..:|.:|..|....|.:.:|.....|| |:....:|..:.....|:...|     ..
  Fly   765 FQPESHESNVLVRSNLGNVSALAFDHLSRNLYWAD-TERAVIEVLSLQTRHRALIRFF-----PG 823

  Fly  1132 EDVPALPESDESKTEQPS------ALEVEQHIASEAEQTPV----EDEHQYDEEEHQQDQEEHQQ 1186
            ::||.      ..|..|:      .|:.::|  |..::.|:    |..|.:         |:...
  Fly   824 QEVPI------GLTVMPAEGYLYVVLKAKRH--SHIDKIPLSGKGEQVHVF---------EDDLG 871

  Fly  1187 DEDEPL-KEVETESL------PEEATTEKFQEPEPEEVNTPLPEELPFDLT-DHSDVNRFNELQS 1243
            |:|..| .:.||:::      ....:...::.|..:.....|  ..|:.|. .|.|: .:|||.:
  Fly   872 DDDIKLVTDYETQTIFWSDSDLGRISYSNYRVPHSQIFRGKL--RRPYSLAMVHHDL-FWNELGT 933

  Fly  1244 ESLILESTTNIDGLQELDNNHIEEEEPAAHAIPH-EEATPN--------PADIVEITTQTMLGLA 1299
            ..:.....:|:...:.:|  .:|:::||| .:|: ..||||        |........|...|..
  Fly   934 PRIYWTHKSNMGPRKVID--IMEKDDPAA-IMPYVPVATPNGIPLAASSPVGQESHPCQQQNGGC 995

  Fly  1300 SRVTLMEPAAPVVTTLMPLMTADEPTPEPVSPAAIPSASLAAIKPGTELRKRVDLG----LEAVS 1360
            |.:.:.|.                           |..|:.....|...|   |.|    :||:.
  Fly   996 SHICVGEG---------------------------PYHSICLCPAGFVYR---DAGNRTCVEALD 1030

  Fly  1361 LGLACSSDRQCQLADPHTVCNRRGVCDCAAGEEGSQCSAE-----RTGCSPGTFQCRSSGVCISW 1420
            ....|.|. :| |...|. ||.|.  ||....:...|..|     :..|||..|.|.|...|:..
  Fly  1031 CEFRCHSG-EC-LTMNHR-CNGRR--DCVDNSDEMNCDEEHRRKPKVLCSPNQFACHSGEQCVDK 1090

  Fly  1421 FFVCDGRADCNDASDEECTHNARLNQTCPTESFRCQRSGRCISRAALCDGRRQCPHGEDELGCDG 1485
            ...||.|.||:|.|||:.......::.|......|. :|:|:..:.:|||...|....|||.|:.
  Fly  1091 ERRCDNRKDCHDHSDEQHCEKFDKSKKCHVHQHGCD-NGKCVDSSLVCDGTNDCGDNSDELLCEA 1154

  Fly  1486 SVKGGNACPEHTFRCGSGECLPEYEYCNAIVSCKDGSDEPPHLCGSRALPNLFMRLIEAGGLLGG 1550
            :    :.|....|:||||.|:.....|:..:.|.|||||... |..|:
  Fly  1155 T----SRCEPGMFQCGSGSCIAGSWECDGRIDCSDGSDEHDK-CVHRS----------------- 1197

  Fly  1551 GRREADAYCP---HRCSNGLCRSTAIVCSGRDGCGDGTDEQTC 1590
                    ||   .||..|.|...::||.|.:.|||.:||..|
  Fly  1198 --------CPPDMQRCLLGQCLDRSLVCDGHNDCGDKSDELNC 1232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ImpE1	NP_524849.2	EB	75..131	CDD:460294
		rne	<795..981	CDD:236766	2/6 (33%)
		LDLa	1404..1437	CDD:238060	15/32 (47%)
		LDLa	1448..1483	CDD:238060	11/34 (32%)
		LDLa	1493..1524	CDD:238060	12/30 (40%)
yl	NP_996433.1	LDLa	90..124	CDD:238060
		LDLa	131..166	CDD:238060
		LDLa	184..216	CDD:238060
		LDLa	227..262	CDD:238060
		LDLa	271..302	CDD:238060
		FXa_inhibition	352..387	CDD:464251
		Ldl_recept_b	442..483	CDD:459654
		LY	466..508	CDD:214531
		Ldl_recept_b	529..569	CDD:459654
		LY	553..595	CDD:214531
		LY	596..637	CDD:214531	0/1 (0%)
		FXa_inhibition	669..700	CDD:464251	7/30 (23%)
		LY	774..815	CDD:214531	9/41 (22%)
		LDLa	1032..1062	CDD:238060	10/34 (29%)
		LDLa	1074..1109	CDD:238060	16/34 (47%)
		LDLa	1118..1152	CDD:238060	11/34 (32%)
		LDLa	1157..1189	CDD:197566	12/31 (39%)
		LDLa	1198..1232	CDD:238060	14/33 (42%)
		LDLa	1243..1279	CDD:238060
		LDLa	1283..1318	CDD:238060
		LDLa	1340..1371	CDD:197566
		FXa_inhibition	1388..1416	CDD:464251
		EGF_CA	1418..1452	CDD:214542