Protein Alignment ImpE1 and Lrp12

DIOPT Version :9

• Sequence 1: NP_001261577.1
• Gene: ImpE1 / 45879
• FlyBaseID: FBgn0001253
• Length: 1616
• Species: Drosophila melanogaster
• Sequence 2: NP_001128355.1
• Gene: Lrp12 / 314941
• RGDID: 1304943
• Length: 858
• Species: Rattus norvegicus
• Alignment Length: 361
• Identity: 71/361 - (19%)
• Similarity: 93/361 - (25%)
• Gaps: 179/361 - (49%)

  Fly  1375 DPHTVCNR----RGVC-----DCAAGEEGSQCSAERT--------------GCSPGTFQCRSS-- 1414
            :||..|::    .|.|     .|.:.:|....|.|..              .|:...|||.|.
  Rat   163 EPHCACDQFRCGNGKCIPEAWKCNSMDECGDSSDEEVCVQDAHPPTTTAFQPCAYNQFQCLSRFT 227

  Fly  1415 --GVCISWFFVCDGRADCNDASDE--------------------------------ECT------ 1439
              ..|:.....|||..||.|..||                                .||
  Rat   228 KVYTCLPESLKCDGNIDCLDLGDEIDCDMPTCGQWLKYFYGTFSSPNYPDFYPPGSNCTWLIDTG 292

  Fly  1440 ------------------------------HNAR------------------------------- 1443
                                          .|.|
  Rat   293 DHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPRKLLRVLTAFDSHAPLTVVSSSGQIRVHFCAD 357

  Fly  1444 -------LNQTCPTESF------RCQRSGRCISRAALCDGRRQCPHGEDELGCDGSVKGGNACPE 1495
                   .|.|...:.|      .|..:..|.:....|||...||:|.||:.|       ..|.:
  Rat   358 KVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGYWHCPNGRDEINC-------TMCQK 415

  Fly  1496 HTFRCG-SGECLPEYEYCNAIVSCKDGSDEPPHLCGSRALPNLFMRLIEAGGLLGGGRREADAYC 1559
            ..|.|. :|.|.|..:.||....|.:||||          .|.|                   :|
  Rat   416 EEFPCSRNGVCYPRSDRCNYQNHCPNGSDE----------KNCF-------------------FC 451

  Fly  1560 P---HRCSNGLCRSTAIVCSGRDGCGDGTDEQTCSV 1592
            .   ..|.|..|...:.||..:|.||||:||::|.|
  Rat   452 QPGNFHCKNNRCVFESWVCDSQDDCGDGSDEESCPV 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ImpE1	NP_001261577.1	EB	75..131	CDD:279949
		LDLa	1404..1437	CDD:238060	14/68 (21%)
		LDLa	1448..1483	CDD:238060	11/40 (28%)
		LDLa	1493..1524	CDD:238060	11/31 (35%)
		LDLa	1561..1590	CDD:238060	12/28 (43%)
Lrp12	NP_001128355.1	CUB	47..158	CDD:238001
		LDLa	166..200	CDD:238060	7/33 (21%)
		LDLa	215..254	CDD:238060	14/38 (37%)
		CUB	267..371	CDD:238001	6/103 (6%)
		LDLa	375..410	CDD:238060	10/34 (29%)
		LDLa	413..448	CDD:238060	13/44 (30%)
		LDLa	451..485	CDD:238060	13/33 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1215
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900