DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ImpE1 and Ldlrad3

DIOPT Version :9

Sequence 1:	NP_001261577.1	Gene:	ImpE1 / 45879	FlyBaseID:	FBgn0001253	Length:	1616	Species:	Drosophila melanogaster
Sequence 2:	NP_849217.2	Gene:	Ldlrad3 / 241576	MGIID:	2138856	Length:	345	Species:	Mus musculus

Alignment Length:	134	Identity:	46/134 - (34%)
Similarity:	63/134 - (47%)	Gaps:	22/134 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  1365 CSSDR------QCQLADPHTVCNRRGVCDCAAGEEGSQCSAERTGCSPGTFQCRSSGVCISWFFV 1423
            ||:.|      ||.           |:.||....:..:|...::.|.|..|.|.|...||...|.
Mouse    37 CSNGRCIPGAWQCD-----------GLPDCFDKSDEKECPKAKSKCGPTFFPCASGIHCIIGRFR 90

  Fly  1424 CDGRADCNDASDEE-CTHNARLNQTCPTESFRCQRSGRCISRAALCDGRRQCPHGEDELGCDGSV 1487
            |:|..||.|.|||| ||.|..|   |.|..:.| |:|.||.::.:|||:..|....||..|:.|:
Mouse    91 CNGFEDCPDGSDEENCTANPLL---CSTARYHC-RNGLCIDKSFICDGQNNCQDNSDEESCESSL 151

  Fly  1488 KGGN 1491
            :.|:
Mouse   152 EPGS 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ImpE1	NP_001261577.1	EB	75..131	CDD:279949
		LDLa	1404..1437	CDD:238060	15/32 (47%)
		LDLa	1448..1483	CDD:238060	13/34 (38%)
		LDLa	1493..1524	CDD:238060
		LDLa	1561..1590	CDD:238060
Ldlrad3	NP_849217.2	LDLa	32..64	CDD:238060	8/37 (22%)
		LDLa	71..106	CDD:238060	17/34 (50%)
		LDLa	113..147	CDD:238060	13/34 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	270..345
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1215
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900