DRSC/TRiP Functional Genomics Resources

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Protein Alignment ImpE1 and Lrp12

DIOPT Version :10

Sequence 1:NP_524849.2 Gene:ImpE1 / 45879 FlyBaseID:FBgn0001253 Length:1616 Species:Drosophila melanogaster
Sequence 2:XP_006520965.1 Gene:Lrp12 / 239393 MGIID:2443132 Length:859 Species:Mus musculus


Alignment Length:201 Identity:53/201 - (26%)
Similarity:69/201 - (34%) Gaps:76/201 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly  1399 AERTGCSPG---TFQCRSSGVCISWFFVCDGRADCNDASDEECTHNARLNQTCPTESFRCQRSGR 1460
            |::...:.|   |:|.  .|.|:.|...|.|                  |..|.||..|      
Mouse   357 ADKVNAARGFNATYQV--DGFCLPWEIPCGG------------------NWGCYTEQQR------ 395

  Fly  1461 CISRAALCDGRRQCPHGEDELGCDGSVKGGNACPEHTFRCG-SGECLPEYEYCNAIVSCKDGSDE 1524
                   |||...||:|.||:.|       ..|.:..|.|. :|.|.|..:.||....|.:||||
Mouse   396 -------CDGYWHCPNGRDEINC-------TMCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDE 446

  Fly  1525 PPHLCGSRALPNLFMRLIEAGGLLGGGRREADAYCP---HRCSNGLCRSTAIVCSGRDGCGDGTD 1586
                      .|.|                   :|.   ..|.|..|...:.||..:|.||||:|
Mouse   447 ----------KNCF-------------------FCQPGNFHCKNNRCVFESWVCDSQDDCGDGSD 482

  Fly  1587 EQTCSV 1592
            |:.|.|
Mouse   483 EENCPV 488

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ImpE1NP_524849.2 EB 75..131 CDD:460294
rne <795..981 CDD:236766
LDLa 1404..1437 CDD:238060 8/35 (23%)
LDLa 1448..1483 CDD:238060 12/34 (35%)
LDLa 1493..1524 CDD:238060 11/31 (35%)
Lrp12XP_006520965.1 CUB 56..158 CDD:238001
LDLa 167..201 CDD:238060
LDLa 216..255 CDD:238060
CUB 268..372 CDD:238001 3/14 (21%)
LDLa 414..449 CDD:238060 13/44 (30%)
LDLa 452..486 CDD:238060 13/33 (39%)
Blue background indicates that the domain is not in the aligned region.

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