DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ImpE1 and Dgcr2

DIOPT Version :9

Sequence 1:	NP_001261577.1	Gene:	ImpE1 / 45879	FlyBaseID:	FBgn0001253	Length:	1616	Species:	Drosophila melanogaster
Sequence 2:	NP_034178.2	Gene:	Dgcr2 / 13356	MGIID:	892866	Length:	549	Species:	Mus musculus

Alignment Length:	129	Identity:	31/129 - (24%)
Similarity:	43/129 - (33%)	Gaps:	45/129 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly  1404 CSPGTFQCRSSGV-CISWFFVCDGRADCNDASDE----ECTHNARLNQTCPTESFRCQRSGRCIS 1463
            |:||.|.|....: ||...:.|||...|.|.|||    |.|..||
Mouse    30 CNPGQFACHGGTIQCIPLPWQCDGWPTCEDKSDEADCPEVTGEAR-------------------- 74

  Fly  1464 RAALCDGRRQCPHGEDELGC-DGSVKGGNACPEHT--------FRCGSGECLPEYEYCNAIVSC 1518
                       |:|::.:.. .|..:||:....||        |....|:|...:.:.....||
Mouse    75 -----------PYGKETVDLRQGRARGGDPTHFHTVNVAQPVRFSSFLGKCPSGWHHYEGTASC 127

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ImpE1	NP_001261577.1	EB	75..131	CDD:279949
		LDLa	1404..1437	CDD:238060	15/37 (41%)
		LDLa	1448..1483	CDD:238060	2/34 (6%)
		LDLa	1493..1524	CDD:238060	7/34 (21%)
		LDLa	1561..1590	CDD:238060
Dgcr2	NP_034178.2	LDLa	30..66	CDD:238060	15/35 (43%)
		CLECT_DGCR2_like	114..266	CDD:153069	3/14 (21%)
		VWC	270..328	CDD:214564
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	416..549
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1215
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900