DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ImpE1 and LOC100536757

DIOPT Version :9

Sequence 1:	NP_001261577.1	Gene:	ImpE1 / 45879	FlyBaseID:	FBgn0001253	Length:	1616	Species:	Drosophila melanogaster
Sequence 2:	XP_021334054.1	Gene:	LOC100536757 / 100536757	-ID:	-	Length:	600	Species:	Danio rerio

Alignment Length:	235	Identity:	66/235 - (28%)
Similarity:	92/235 - (39%)	Gaps:	66/235 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  1361 LGLACSSDRQCQLADPHTVCNRRGVCDCAAGEEGSQCSAERTGCSPGTFQCRSSGVCISWFFVCD 1425
            |...|::.|...|:   :.|:  .|.||..|.:...|    ..|:.|:|.|.:|..|:|...|||
Zfish    41 LQFVCANSRCVSLS---SRCD--AVNDCGDGSDEISC----WNCTNGSFHCVASESCVSSSSVCD 96

  Fly  1426 GRADCNDASDEE---CTHNARLNQTCPTESFRCQRSGRCISRAALCDGRRQCPHGEDELGCDG-- 1485
            ||.||.|.:||:   ||..::. |.|....|.| .:|:|:..:..||....|..|.||..||.
Zfish    97 GRPDCADGADEQLDTCTSFSQA-QPCARSEFTC-TNGQCVPNSWRCDHSSDCKDGSDEEDCDHNE 159

  Fly  1486 -SVKGGNACPEHT-------FRCG--SGECLPEYEYCNAIVSCKDGSDEPPHLCGSRALPNLFMR 1540
             :|..|..  .||       |||.  .|..|.:..:|..:..|.|..     :|
Zfish   160 CAVNNGGC--SHTCIDLPFGFRCDCPKGMRLVQDTHCEVVDQCLDAD-----VC----------- 206

  Fly  1541 LIEAGGLLGGGRREADAYCPHRCSNGLCRSTAIVCSGRDG 1580
                           |..|.|  |||     ::||..:||
Zfish   207 ---------------DQICVH--SNG-----SVVCDCQDG 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ImpE1	NP_001261577.1	EB	75..131	CDD:279949
		LDLa	1404..1437	CDD:238060	16/32 (50%)
		LDLa	1448..1483	CDD:238060	11/34 (32%)
		LDLa	1493..1524	CDD:238060	10/39 (26%)
		LDLa	1561..1590	CDD:238060	8/20 (40%)
LOC100536757	XP_021334054.1	LDLa	38..72	CDD:238060	9/35 (26%)
		PRKCSH-like	<45..>112	CDD:193472	26/75 (35%)
		LDLa	121..155	CDD:238060	11/34 (32%)
		FXa_inhibition	160..193	CDD:317114	9/34 (26%)
		Ldl_recept_b	367..407	CDD:278487
		LY	393..433	CDD:214531
		LY	434..476	CDD:214531
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1215
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900