Protein Alignment Hex-A and hk1

DIOPT Version :10

• Sequence 1: NP_524848.1
• Gene: Hex-A / 45875
• FlyBaseID: FBgn0001186
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_998417.1
• Gene: hk1 / 406791
• ZFINID: ZDB-GENE-040426-2848
• Length: 918
• Species: Danio rerio
• Alignment Length: 464
• Identity: 218/464 - (46%)
• Similarity: 307/464 - (66%)
• Gaps: 21/464 - (4%)

  Fly    84 ALLSA-----AEKSKMVHELCQQLLLTDEQVQELCYRILHELRRGLAKDTHPKANVKCFVTYVQD 143
            ||::|     |::.:.:.|..::..||.:|:.|:..|:..|::.||:|.|...|.||...|||:.
Zfish   454 ALVTAWAYRLADQERQIAETLEEFRLTKDQLLEVKKRMRTEIQNGLSKSTQNTATVKMLPTYVRS 518

  Fly   144 LPNGNERGKFLALDLGGTNFRVLLIHLQ--ENNDFQMESRIYAIPQHIMIGSGTQLFDHIAECLS 206
            .|:|:|.|.|||||||||||||||:.::  :....:|.::|||||..:|.|:|.:|||||..|:|
Zfish   519 TPDGSENGDFLALDLGGTNFRVLLVKIRSGKRRTVEMHNKIYAIPIEVMQGTGEELFDHIVYCIS 583

  Fly   207 NFMAEHNVYKERLPLGFTFSFPLRQLGLTKGLLETWTKGFNCAGVVNEDVVQLLKDAIARRGDVQ 271
            :|:....:...|||||||||||.||..|..|||..|||||.......||||.||::.|.||.:..
Zfish   584 DFLDYMGMKNARLPLGFTFSFPCRQTSLDAGLLVNWTKGFKATDCEGEDVVGLLREGIKRREEFD 648

  Fly   272 IDVCAILNDTTGTLMSCAWKNHNCKIGLIVGTGANACYMERVEEAELFAAEDPRKKHVLINTEWG 336
            :||.||:|||.||:|:||::...|::|||.|||:||||||.:...|..:.|:.|   :.:|.|||
Zfish   649 LDVVAIVNDTVGTMMTCAYEEPTCEVGLIAGTGSNACYMEEMRNIETVSGEEGR---MCVNMEWG 710

  Fly   337 AFGDNGALDFVRTEFDRDIDVHSINPGKQTFEKMISGMYMGELVRLVLVKMTQAGILFNGQDSEV 401
            ||||||.||.:||::|..:|..|:|.|||.:|||.||||:||:||.:|:.:|:.|.||.||.||.
Zfish   711 AFGDNGCLDDIRTKYDDAVDDLSLNAGKQKYEKMCSGMYLGEIVRNILIDLTKRGFLFRGQISET 775

  Fly   402 LNTRGLFFTKYVSEIEADEPGNFTNCRLVLEELGLTNATDGDCANVRYICECVSKRAAHLVSAGI 466
            |.|||:|.||::|:||:|... ....|.:|:.|||.:..| |...|:.:|..||:|||.|..||:
Zfish   776 LKTRGIFETKFLSQIESDRLA-LLQVRSILQHLGLDSTCD-DSIIVKEVCGAVSRRAAQLCGAGM 838

  Fly   467 ATLINK------MDEPTVTVGVDGSVYRFHPKFHNLMVEKISQLI-KPGITFDLMLSEDGSGRGA 524
            |.:::|      :|...:||||||::|:.||.|..:|.:.:.:|. |..:||  :|||||||:||
Zfish   839 AAVVDKIRENRGLDHLDITVGVDGTLYKLHPHFSRIMHQTVKELAPKCNVTF--LLSEDGSGKGA 901

  Fly   525 ALVAAVACR 533
            ||:.||.||
Zfish   902 ALITAVGCR 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-A	NP_524848.1	ASKHA_NBD_HK_meta	104..529	CDD:466869	209/433 (48%)
hk1	NP_998417.1	ASKHA_NBD_HK1_meta_rpt1	2..474	CDD:466974	5/19 (26%)
		ASKHA_NBD_HK1_meta_rpt2	478..911	CDD:466977	213/440 (48%)