Protein Alignment Hex-A and hxk1

DIOPT Version :10

• Sequence 1: NP_524848.1
• Gene: Hex-A / 45875
• FlyBaseID: FBgn0001186
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_592948.1
• Gene: hxk1 / 2542634
• PomBaseID: SPAC24H6.04
• Length: 484
• Species: Schizosaccharomyces pombe
• Alignment Length: 450
• Identity: 169/450 - (37%)
• Similarity: 255/450 - (56%)
• Gaps: 13/450 - (2%)

  Fly    97 ELCQQLLLTDEQVQELCYRILHELRRGLAKDTHPKANVKCFVTYVQDLPNGNERGKFLALDLGGT 161
            ||.:|..:..|.:..:..|.:.||.:||.  |:| .:|....|::...|:|||.|.:||||||||
pombe    33 ELEEQFTIPTELLHRVTDRFVSELYKGLT--TNP-GDVPMVPTWIIGTPDGNEHGSYLALDLGGT 94

  Fly   162 NFRVLLIHLQENNDFQMESRIYAIPQHIMIGSGTQLFDHIAECLSNFMAE-HNVYKERLPLGFTF 225
            |.||..:.:|.|..|.:....|.:||.:.:|:...|||:||:|:..|:.| |....:.|.:||||
pombe    95 NLRVCAVEVQGNGKFDITQSKYRLPQELKVGTREALFDYIADCIKKFVEEVHPGKSQNLEIGFTF 159

  Fly   226 SFPLRQLGLTKGLLETWTKGFNCAGVVNEDVVQLLKDAIARRGDVQIDVCAILNDTTGTLMSCAW 290
            |:|..|..:....|..|||||:..||..|.|..||..|:.|.|...:.:.|||:||||||::..:
pombe   160 SYPCVQRSINDASLVAWTKGFDIDGVEGESVGPLLSAALKRVGCNNVRLNAILSDTTGTLVASNY 224

  Fly   291 KNHNCKIGLIVGTGANACYMERVEE-AELFAAEDPRKKHVLINTEWGAFGDNGALDFVRTEFDRD 354
            .:...:||:|.|||.||||:|:..| .:|...:.|...:::||.||..| ||..:...||::|..
pombe   225 ASPGTEIGVIFGTGCNACYIEKFSEIPKLHKYDFPEDMNMIINCEWCDF-DNQHVVLPRTKYDVA 288

  Fly   355 IDVHSINPGKQTFEKMISGMYMGELVRLVLVKMTQAGILFNGQDSEVLNTRGLFFTKYVSEIEAD 419
            ||..|..||.||:||||:|.|:|:::|.:|:.:.:.|.||||||...:.......|..:|.||.|
pombe   289 IDEESPRPGLQTYEKMIAGCYLGDILRRILLDLYEQGALFNGQDVTKIRDPLAMDTSVLSAIEVD 353

  Fly   420 EPGNFTNCRLVLEELGLTNATDGDCANVRYICECVSKRAAHLVSAGIATLINKMDEPTVTVGVDG 484
            ...|....:.:.||......|:.:...:|..||.:..|:|.|.:.|:..|:.||::|::.||.||
pombe   354 PFENLDETQTLFEETYGLKTTEEERQFIRRACELIGTRSARLSACGVCALVRKMNKPSMIVGTDG 418

  Fly   485 SVYRFHPKFHNLMVEKISQLIKPGITFDLML--SEDGSGRGAALVAAV-----ACREDIL 537
            |||..:|:|.:.:.:....::...|...::.  :|||||.|||||:|:     |...|||
pombe   419 SVYNLYPRFKDRLAQAFKDILGEEIGSKVVTIPAEDGSGVGAALVSALEAKGKALTSDIL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-A	NP_524848.1	ASKHA_NBD_HK_meta	104..529	CDD:466869	161/428 (38%)
hxk1	NP_592948.1	ASKHA_ATPase-like	42..468	CDD:483947	162/429 (38%)