Protein Alignment Hex-A and hxk-3

DIOPT Version :10

• Sequence 1: NP_524848.1
• Gene: Hex-A / 45875
• FlyBaseID: FBgn0001186
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001370784.1
• Gene: hxk-3 / 176958
• WormBaseID: WBGene00022306
• Length: 451
• Species: Caenorhabditis elegans
• Alignment Length: 443
• Identity: 158/443 - (35%)
• Similarity: 259/443 - (58%)
• Gaps: 6/443 - (1%)

  Fly    95 VHELCQQLLLTDEQVQELCYRILHELRRGLAKDTHPKANVKCFVTYVQDLPNGNERGKFLALDLG 159
            |.|:..:..|..||:||:..::..:::.||||.  ..:::....:||..||:|.|.||::|:||.
 Worm     8 VEEILAKFRLNREQLQEISEKVEQQMKMGLAKT--QGSSIAMLPSYVPALPDGTETGKYVAIDLS 70

  Fly   160 GTNFRVLLIHLQENNDFQMESRI-YAIPQHIMIGSGTQLFDHIAECLSNFMAEHNVYKERLPLGF 223
            |.|.|::|:.:...........: |.:..|:|.|:|.|||..|..||..|:.|..:....||:||
 Worm    71 GKNLRIMLLTMNGAGTTPTHETVNYIVANHVMKGTGDQLFTFIVNCLQRFLQEFGLVDANLPIGF 135

  Fly   224 TFSFPLRQLGLTKGLLETWTKGFNCAGVVNEDVVQLLKDAIARRGDVQIDVCAILNDTTGTLMSC 288
            .||:|...|.:....|..|||||:....:..|:|.||::|:......::.:.|::|||.|.|.:.
 Worm   136 VFSYPCELLSIRSARLLWWTKGFDIKDCLQRDIVALLEEALEMNMSTKVSIKAVMNDTVGQLAAA 200

  Fly   289 AWK-NHNCKIGLIVGTGANACYMERVEEAELFAAEDPRKKH--VLINTEWGAFGDNGALDFVRTE 350
            |.| ...|.||:::|.|.|:.|:|:......|.|:.....|  :::.|||..||.:|.||.:.|:
 Worm   201 AHKYGPECTIGVVIGYGCNSSYLEKTSRITKFDAKARGYDHDNMIVVTEWEEFGKHGELDDILTQ 265

  Fly   351 FDRDIDVHSINPGKQTFEKMISGMYMGELVRLVLVKMTQAGILFNGQDSEVLNTRGLFFTKYVSE 415
            |||::|..|::.|||..:|:...:|:||:||.||.::....:||.||..|.|:....|.|||:||
 Worm   266 FDREVDAASVHKGKQLIDKLCGALYIGEVVRRVLSQLVLDRVLFEGQSCEKLDEDESFPTKYISE 330

  Fly   416 IEADEPGNFTNCRLVLEELGLTNATDGDCANVRYICECVSKRAAHLVSAGIATLINKMDEPTVTV 480
            |..:|.|.|..||.:.|||.:.....||...:|.:|:.:|:|.|.:|:|.|:.|:..::..:|.:
 Worm   331 ILGEEEGVFKACRRICEELEVEMHGTGDYIIIREVCDVISRRGASIVAAAISALLRHLELSSVKI 395

  Fly   481 GVDGSVYRFHPKFHNLMVEKISQLIKPGITFDLMLSEDGSGRGAALVAAVACR 533
            ||.|::.:|||.:|.::.||:.:|....:.|:|:.:::||.:||||:||||.|
 Worm   396 GVGGALIQFHPTYHQMLKEKLEELTPITMKFELVPADEGSCQGAALIAAVAER 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-A	NP_524848.1	ASKHA_NBD_HK_meta	104..529	CDD:466869	151/428 (35%)
hxk-3	NP_001370784.1	ASKHA_NBD_HK_meta	16..444	CDD:466869	151/429 (35%)