Protein Alignment Hex-A and Hex-t1

DIOPT Version :9

• Sequence 1: NP_524848.1
• Gene: Hex-A / 45875
• FlyBaseID: FBgn0001186
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_788744.1
• Gene: Hex-t1 / 117364
• FlyBaseID: FBgn0042711
• Length: 465
• Species: Drosophila melanogaster
• Alignment Length: 437
• Identity: 159/437 - (36%)
• Similarity: 276/437 - (63%)
• Gaps: 1/437 - (0%)

  Fly    95 VHELCQQLLLTDEQVQELCYRILHELRRGLAKDTHPKANVKCFVTYVQDLPNGNERGKFLALDLG 159
            |:::|:....:.:.::::...:..|:..||::|.|.::.|.|.::||||||.|.|||:||||::.
  Fly    14 VYKVCKLFNPSIDDLEKIKNAMDREITMGLSRDHHDRSTVPCHLSYVQDLPTGRERGQFLALEMM 78

  Fly   160 GTNFRVLLIHLQENNDFQMESRIYAIPQHIMIGSGTQLFDHIAECLSNFMAEHNVYKERLPLGFT 224
            .||.|::|:......|....|:...:|..:..|.||::|..:|..::||:.|..|.|:.||||..
  Fly    79 PTNCRIMLVKFSSERDIYTSSKCVIMPHTVAAGRGTEVFTFLATSIANFVKEKKVDKDNLPLGIA 143

  Fly   225 FSFPLRQLGLTKGLLETWTKGFNCAGVVNEDVVQLLKDAIARRGDVQIDVCAILNDTTGTLMSCA 289
            |:|.|::|.|..|:|.:|||.|...|.:.:||||||:||:|:..::.:||..|:|...|:|::..
  Fly   144 FAFTLKKLALDVGILVSWTKEFGAQGAIGKDVVQLLRDALAKFPEISVDVMGIINVGAGSLLALC 208

  Fly   290 WKNHNCKIGLIVGTGANACYMERVEEAELFAAEDPRKKHVLINTEWGAFGDNGALDFVRTEFDRD 354
            |...:.:||||:|:.||:||:||||..|.:..::.||. ::||::|..|||.|.|||:|.|:||.
  Fly   209 WAQPDTRIGLIMGSIANSCYVERVERCETYEGDEYRKL-MIINSDWAHFGDTGQLDFIRNEYDRQ 272

  Fly   355 IDVHSINPGKQTFEKMISGMYMGELVRLVLVKMTQAGILFNGQDSEVLNTRGLFFTKYVSEIEAD 419
            :|..|||||.:.:||....:.||||||::::::.::|.:|.....:.:..:.......:.||.:|
  Fly   273 LDTESINPGTRIYEKFSGALCMGELVRIIVLRLMKSGAIFAEDRRDYIGIQWKLDMVSLIEIVSD 337

  Fly   420 EPGNFTNCRLVLEELGLTNATDGDCANVRYICECVSKRAAHLVSAGIATLINKMDEPTVTVGVDG 484
            .||.:|..:.|:::..:.:..:.|.|.::|||:.|:.|||.||::|::.||::|..|.:::.|||
  Fly   338 PPGVYTKAQEVMDKFRIRHCKERDLAALKYICDTVTNRAAMLVASGVSCLIDRMRLPQISIAVDG 402

  Fly   485 SVYRFHPKFHNLMVEKISQLIKPGITFDLMLSEDGSGRGAALVAAVA 531
            .:||.||.|..::.:....|..|...|:.::::|..|.|||::|.:|
  Fly   403 GIYRLHPTFSTVLNKYTRLLADPNYNFEFVITQDSCGVGAAIMAGMA 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-A	NP_524848.1	Hexokinase_1	95..290	CDD:395278	71/194 (37%)
		Hexokinase_2	296..530	CDD:397683	86/233 (37%)
Hex-t1	NP_788744.1	COG5026	13..446	CDD:227359	157/432 (36%)
		Hexokinase_1	13..209	CDD:278764	71/194 (37%)
		Hexokinase_2	215..448	CDD:281689	86/233 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448963
Domainoid	1	1.000	128	1.000	Domainoid score	I1730
eggNOG	1	0.900	-	-		E1_COG5026
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	246	1.000	Inparanoid score	I1050
Isobase	1	0.950	-	0	Normalized mean entropy	S1223
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1153545at2759
OrthoFinder	1	1.000	-	-		FOG0000301
OrthoInspector	1	1.000	-	-		mtm1201
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19443
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X170
	11	10.850