Protein Alignment Hex-A and LOC100492955

DIOPT Version :9

• Sequence 1: NP_524848.1
• Gene: Hex-A / 45875
• FlyBaseID: FBgn0001186
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_002936995.4
• Gene: LOC100492955 / 100492955
• -ID: -
• Length: 728
• Species: Xenopus tropicalis
• Alignment Length: 461
• Identity: 176/461 - (38%)
• Similarity: 273/461 - (59%)
• Gaps: 28/461 - (6%)

  Fly    84 ALLSAAEKSK----MVHELCQQLLLTDEQVQELCYRILHELRRGLAKDTHPKANVKCFVTYVQDL 144
            ||::|.||.:    .:..|.:.|.::::.:||:..|:..|:.|||.|:||..|.:|...||:...
 Frog   269 ALVTAVEKRRTKIEKIENLLKPLQMSEKILQEVQARMRQEMERGLEKETHQCAFLKMLPTYICSK 333

  Fly   145 PNGNERGKFLALDLGGTNFRVLLIHL-----QENNDFQMESRIYAIPQHIMIGSGTQLFDHIAEC 204
            |.|||.|:|:.|:|||.|..::.:.:     :|.:..:   ..|.:||::|.|:|.:||||||.|
 Frog   334 PTGNETGEFIVLELGGKNMHIVHVRIGGRPEEERSPIK---ETYTLPQNLMKGTGEELFDHIASC 395

  Fly   205 LSNFMAEHNVYKERLPLGFTFSFPLRQLGLTKGLLETWTKGFNCAGVVNEDVVQLLKDAIARRGD 269
            |.:|...||:...::.|.|.|.||.:|..|.:|.|..|||||..:|...::||:||:.||.::.:
 Frog   396 LLDFQKVHNLGGNKMYLSFVFPFPCKQTALNQGCLIKWTKGFAASGCEEKNVVELLERAIKQKRE 460

  Fly   270 VQIDVCAILNDTTGTLMSCAWKNHNCKIGLIVGTGANACYMERVEEAELFAAEDPRKKHVLINTE 334
            :.:.|.|::||||.|:|:...|:::|:||||||||.||||||..:..::  ..:.....:.:|.|
 Frog   461 LNMTVIALVNDTTSTMMAGCSKHNSCEIGLIVGTGTNACYMEETKNIQM--EMENMSGQMCVNME 523

  Fly   335 WGAFGDNGALDFVRTEFDRDIDVHSINPGKQTFEKMISGMYMGELVRLVLVKMTQAGILFNGQDS 399
            ||||||||.||.:.|:||:::||.|:|||||.|||||.|||:|::|..||:.:.....|.:..:.
 Frog   524 WGAFGDNGCLDDIITDFDQEVDVSSVNPGKQRFEKMIGGMYLGQIVHRVLIGLAHNDFLLSNLEP 588

  Fly   400 EVLNTRGLFFTKYVSEIEADEPGNFTNCRLVLEELGLTNATDGDCANVRYICECVSKRAAHLVSA 464
            .    ..|...|::..||.|:. :....|.||.:.||..|.| :...|:.:|..||.|||.|.:|
 Frog   589 R----ENLLELKHLCLIEGDKL-SLVEVRSVLLKCGLNCALD-EVKMVKIVCRAVSTRAAQLCAA 647

  Fly   465 GIATLINK------MDEPTVTVGVDGSVYRFHPKFHNLMVEKISQLIKPGITFDLMLSEDGSGRG 523
            |:|.::.|      :|...:.|||:|.:|..||.|.:.|...:.:| .|..|...:.| |..|:|
 Frog   648 GVAAVVEKIRENRALDHLKIAVGVNGPLYEDHPNFKDEMESTLKKL-APCCTVTFVQS-DSKGKG 710

  Fly   524 AALVAA 529
            |||::|
 Frog   711 AALISA 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-A	NP_524848.1	Hexokinase_1	95..290	CDD:395278	74/199 (37%)
		Hexokinase_2	296..530	CDD:397683	95/240 (40%)
LOC100492955	XP_002936995.4	Hexokinase_2	<195..274	CDD:397683	2/4 (50%)
		Hexokinase_1	283..480	CDD:395278	74/199 (37%)
		Hexokinase_2	487..717	CDD:397683	95/240 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56451
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000301
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X170
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920