Protein Alignment Hex-A and Hkdc1

DIOPT Version :10

• Sequence 1: NP_524848.1
• Gene: Hex-A / 45875
• FlyBaseID: FBgn0001186
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001419083.1
• Gene: Hkdc1 / 100364027
• RGDID: 2321830
• Length: 915
• Species: Rattus norvegicus
• Alignment Length: 479
• Identity: 213/479 - (44%)
• Similarity: 306/479 - (63%)
• Gaps: 26/479 - (5%)

  Fly    61 ATTNATTATATTTNLTTHSPQQIALLSAAEKSKMVHELCQQLLLTDEQVQELCYRILHELRRGLA 125
            :|..|...||..:.:..             :.|.:.::.....||.||:..:..::..||..||.
  Rat   449 STKGAAMVTAVASRVQA-------------QRKQIDKVLALFHLTREQLLGVRDKMRAELEYGLK 500

  Fly   126 KDTHPKANVKCFVTYVQDLPNGNERGKFLALDLGGTNFRVLLIHLQENNDFQMESRIYAIPQHIM 190
            |.||..|.||...|||..:|:|.|:|||||||||||||||||:.:::.: .:|.::|:|||..||
  Rat   501 KKTHALATVKMLPTYVYGMPDGTEKGKFLALDLGGTNFRVLLVKIRKRS-VRMYNKIFAIPLEIM 564

  Fly   191 IGSGTQLFDHIAECLSNFMAEHNVYKERLPLGFTFSFPLRQLGLTKGLLETWTKGFNCAGVVNED 255
            .|:|.:|||||.:|:::|:....:...:||||||||||.||..:.||.|..|||||.......||
  Rat   565 QGTGEELFDHIVQCIADFLDYMGLKGAQLPLGFTFSFPCRQTCIDKGTLVGWTKGFKATDCEGED 629

  Fly   256 VVQLLKDAIARRGDVQIDVCAILNDTTGTLMSCAWKNHNCKIGLIVGTGANACYMERVEEAELFA 320
            ||.:|::||.||.:..:|:.||:|||.||:|:|.:::..|:||||.|||:|.||||.:...||..
  Rat   630 VVDMLREAIKRRNEFDLDIVAIVNDTVGTMMTCGYEDPRCEIGLIAGTGSNVCYMEEMRNIELVD 694

  Fly   321 AEDPRKKHVLINTEWGAFGDNGALDFVRTEFDRDIDVHSINPGKQTFEKMISGMYMGELVRLVLV 385
            .::.|   :.:|||||.|||||.:|.:||::|:::|..|:|.|||.:|||.||||:||:||.:|:
  Rat   695 GDEGR---MCVNTEWGGFGDNGCIDDIRTQYDKEVDEGSLNAGKQRYEKMTSGMYLGEIVRRILI 756

  Fly   386 KMTQAGILFNGQDSEVLNTRGLFFTKYVSEIEADEPGNFTNCRLVLEELGLTNATDGDCANVRYI 450
            .:|:.|:||.||.||.|.|||:|.||::|:||:|... ....|.:|::||| ::|..|...|:.:
  Rat   757 DLTRQGLLFRGQISERLRTRGIFETKFLSQIESDRLA-LLQVRRILQQLGL-DSTCEDSIVVKEV 819

  Fly   451 CECVSKRAAHLVSAGIATLINKMDEP------TVTVGVDGSVYRFHPKFHNLMVEKISQLIKPGI 509
            |..||:|||.:..||:|.::.|..|.      .|||||||::|:.||.|..::.|.:..| .|..
  Rat   820 CGAVSRRAAQMCGAGMAAIVEKRREDQGLQHFKVTVGVDGTLYKLHPHFSRILQETVKDL-APQC 883

  Fly   510 TFDLMLSEDGSGRGAALVAAVACR 533
            ....||||||||:||||:.|||.|
  Rat   884 DVTFMLSEDGSGKGAALITAVAKR 907

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-A	NP_524848.1	ASKHA_NBD_HK_meta	104..529	CDD:466869	204/430 (47%)
Hkdc1	NP_001419083.1	ASKHA_NBD_HKDC1_meta_rpt1	30..458	CDD:466976	2/8 (25%)
		ASKHA_NBD_HKDC1_meta_rpt2	479..908	CDD:466980	208/436 (48%)