Protein Alignment grau and LOC4577300

DIOPT Version :10

• Sequence 1: NP_788422.1
• Gene: grau / 45871
• FlyBaseID: FBgn0001133
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: XP_562408.4
• Gene: LOC4577300 / 4577300
• VectorBaseID: AGAMI1_012271
• Length: 851
• Species: Anopheles gambiae
• Alignment Length: 851
• Identity: 164/851 - (19%)
• Similarity: 265/851 - (31%)
• Gaps: 348/851 - (40%)

  Fly     4 CRLCLRGVSGAQMCLQIFDVDSGESKVAEVLRQHFWFEVLPNDEISKVICNVCWTQVSEFHQFYV 68
            |.|||  .|.::..|.:|...:.:..:|.|:.:|.||::.|..|  ..||..|||.:..||::|.
Mosquito     7 CALCL--TSESKWLLDVFSESNRDLHMASVISKHLWFDLNPASE--PHICMDCWTTIHNFHRYYT 67

  Fly    69 SIQEAQVIYATTSKFKQDPEMVNTSWPEEVLMPADVLAVD-NDVGAQINVNPLDELDLSQPMSPE 132
            .:   :.::........|....|....|  |...:.|..| .::..|:...|....|.|:.....
Mosquito    68 KL---EALHDRDDGITVDESTANDEMGE--LKNIEFLEEDAEELRMQMKQIPNASYDGSEEQESP 127

  Fly   133 DSKVGIKTERQSPDMELLFEDANNEQDED--------YEDDEDDD-------------------- 169
            .....|:..::|.|.|....:...|||.|        :|:.|..|
Mosquito   128 SRGSAIERNKKSNDQEFSLFEIEVEQDGDGTVYRLDAFENHEQTDRPESETRKQPVILNGQMKPS 192

  Fly   170 ---------------TDDLIVTRS-GRKRKR---------------------------------D 185
                           .|:..|.|. ||.||:                                 |
Mosquito   193 SAGESSTVAIDFFVPEDEPPVKRGRGRPRKQIKVEPDTSLRIIKKENNSSMDEHNTSLDSTGGND 257

  Fly   186 VAKPAKTKRG----TVSVGRKG----------KEKMVVKR------------GPPKRIFKMERLP 224
            ...|.|.:||    ..||.|..          |.::..:|            .|.:|..::.:..
Mosquito   258 EQVPVKRRRGRPPKNASVQRNASPIVPTPRAIKREVKTEREDEDAPDSGGTSRPERRSTRVRKAK 322

  Fly   225 PFC--------KEDEE-------------------------LIKRYIVMG--------CELCIFL 248
            .|.        :||||                         .::|.:.|.        |.|
Mosquito   323 YFSDMEQDSNEEEDEEEEVQEEETEPSEYEPGDDPEYEARLQLQRELNMDDFAFYEYQCSL---- 383

  Fly   249 AEDFDGIRE-----------------------------HFKDKHPDERPYIKC--CGRKLNKRCL 282
             |:..|.|:                             |::.:| ::.||:||  |.:|.:...:
Mosquito   384 -ENDHGARDNKIFQYVDEFACHVCEEKVTFKRFAEAHLHYRVEH-NQPPYLKCPRCEKKCHTPGM 446

  Fly   283 IQEHARRHENPEYIKCKDCGKVFANSSVLRAHWLVHHVP-DEECDFQCEDCGKRFSRRNLLELHK 346
            ...|...|::||..||:.|||....:..|:.|..||... :|...:.|..|.::|...:|.|.|:
Mosquito   447 FVSHMETHDDPEKNKCQICGKYTDCNISLKKHMRVHQSQLEENLPYPCSLCKRKFETEDLREKHE 511

  Fly   347 GSHVP---VNERK------------FICPQCPKHNAFATEY----HMQVHISMQHRKAANI-CHV 391
            ..|||   |.:.|            ..|..|.:....:..|    .::.|:..:|.|...: |..
Mosquito   512 KLHVPKPHVPKEKGPDHEVLDFYKVIACDICEEEQTDSPTYDNLSDLRAHMVKEHNKNMYLRCPY 576

  Fly   392 CGKKIKDKAVFEKHVRLHFEESGPRIKCPRPD---CESWLKDEDNLKQHLRRHN-----DEG-KL 447
            |..:..::.....|:.:|          ..||   ||...:...||.||:.:.:     ||. |.
Mosquito   577 CSTRQVNRQQVITHIDMH----------NNPDKYRCEVCKEVHQNLHQHMMKAHAPTTADEADKK 631

  Fly   448 FICSECGKS------------------------CK---NSRALIGHKRYSHSNVI---------- 475
            :.|.:||:|                        |.   |.||...|||.:|::::
Mosquito   632 YKCDQCGRSFNFLANLKMHVDCVHGVKDVKCNVCNKFFNYRAYRTHKRTAHTDLMLMCELCPKMF 696

  Fly   476 ----------------------------------------------------------------- 475
                                                                             
Mosquito   697 KNRKSFEVHKASHEGLMLRMTNCVLCGKLIRTCSMSKHMKTIHSEEDPVNCDLCGKMFRTTFHMK 761

  Fly   476 ---------------YTCEQCGKTFKKDISLKEHMAQHTGEPLYKCPFCPRTFNSNANMHSHKKK 525
                           :.||.|||.|...:::.|||..||....|:|.||.::|...:|::.|:||
Mosquito   762 RHQKNTCEVTMDSRSFKCEVCGKGFSTKLTMMEHMTTHTRTNQYQCAFCFKSFGYISNLYKHRKK 826

  Fly   526 MHPVEW 531
            .||:||
Mosquito   827 AHPLEW 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grau	NP_788422.1	zf-AD	3..74	CDD:462262	22/69 (32%)
		C2H2 Zn finger	272..290	CDD:275368	4/19 (21%)
		COG5048	<296..453	CDD:227381	43/186 (23%)
		C2H2 Zn finger	298..318	CDD:275368	6/19 (32%)
		C2H2 Zn finger	329..349	CDD:275368	6/19 (32%)
		C2H2 Zn finger	359..409	CDD:275368	9/54 (17%)
		C2H2 Zn finger	360..378	CDD:275370	2/21 (10%)
		zf-C2H2_8	419..502	CDD:464935	34/208 (16%)
		C2H2 Zn finger	450..471	CDD:275368	11/47 (23%)
		C2H2 Zn finger	478..498	CDD:275368	9/19 (47%)
		C2H2 Zn finger	506..524	CDD:275368	6/17 (35%)
LOC4577300	XP_562408.4	None