Protein Alignment grau and eor-1

DIOPT Version :10

• Sequence 1: NP_788422.1
• Gene: grau / 45871
• FlyBaseID: FBgn0001133
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_001367921.1
• Gene: eor-1 / 177249
• WormBaseID: WBGene00001324
• Length: 909
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 138/599 - (23%)
• Similarity: 210/599 - (35%)
• Gaps: 143/599 - (23%)

  Fly    41 EVLPNDEISKVICNVCWTQVSEFHQFYVSIQEAQVIYATTSKFKQDPEMVNTSWPEEVLMPADVL 105
            ||...:||.:::...|     ||.:          :.|.|.:|..|...:.:...:...:...|:
 Worm   216 EVSKREEIFRLLLESC-----EFRE----------VSADTLEFLLDYSPLLSKSQKSRFLLLHVM 265

  Fly   106 AVDNDVGAQINVNPLDELDLSQPMSPEDSKVGIKTERQS-PDMELLFEDANNEQDEDYEDDEDDD 169
            ..:|                   |..|.....:.:.||. .|:.:|.:.:..|.|.....|.::|
 Worm   266 ETNN-------------------MLMEKYSTQLSSLRQKIVDLPILHDPSQFEDDIYDSSDSEED 311

  Fly   170 TDDLI---------VTRSGRKRKRDVAKPAKTKRGTVSVGRKGKEKMVVKRGPPKRIFK--MERL 223
            .||.|         |...|    .||....|.|    ...:.|.||..:||  ||.:.|  :..:
 Worm   312 PDDYIADGHPTSAQVVEYG----NDVNNRLKMK----IAFQPGNEKKRLKR--PKGMKKHHLHPI 366

  Fly   224 PPFCK---------EDEELIKRYIVMGCELCIFLAE----DFDGIREHFKDKHPDERPYIKC--C 273
            ||...         :::|:...|.....|.|.....    |.|...:  ::..|||.....|  |
 Worm   367 PPINATENESIPWIDEDEIDGVYATCSLEGCHTYGPVDNLDPDDCED--EEDQPDENGPSTCIFC 429

  Fly   274 GRKLNKRCLIQEHARRHENPE-YIKCKDC------GKVFANSSVLRAHWLVHHVPDEECDFQCED 331
            |.:.....|:::|..||.|.. |..|..|      .|.|.....  .||       .|..::||.
 Worm   430 GLRTANEELLEKHKARHHNRNTYYMCHLCEFETNWSKQFYLHCA--EHW-------TEIPYRCET 485

  Fly   332 CGKRFSRRNLLEL--HKGSHVPVNERKFICPQC-----PKHNAFATEYHMQVHISMQHRKAANIC 389
            |  .|:...:.|.  |:..|  .:||.|.|.:|     .:...||   |.::|..:..|...  |
 Worm   486 C--PFTSNEIQEFLTHRLQH--TDERFFKCGECAWKGRTRSQLFA---HERMHSVLDDRSLH--C 541

  Fly   390 HVCGKKIKDKAVFEKHVRLHFEESGPRIKCPRP----DCESWLKDEDNLKQHLRRHNDEGKLFIC 450
            ..||:..:..:..:.||..|.:        |||    ||....|..|:|..|.|:|.  |..|.|
 Worm   542 EECGRGFQQHSTLDHHVASHND--------PRPYICEDCGFATKTADHLSLHRRQHT--GDNFSC 596

  Fly   451 --SECGKSCKNSRALIGHKRYSHSNVIYTCEQCGKTFKKDISLKEHMAQHTGEPLYKCPFCPRTF 513
              :.|..|......|..|.|...:...:.|:.||:.|.:...|..|...|..|..:||..|....
 Worm   597 HIAGCDYSSTKKSQLAAHLRTHMAVRAHLCKICGRGFIEKSHLVRHERIHLEEKPFKCDQCEYAS 661

  Fly   514 NSNANMHSHKKKMHPVEWDIWRKT--KTGSSQKVL---------PSAQVAQMFRDDA-------- 559
            :....:..|..|.|..|...::||  :....|::|         |.|....:..|||
 Worm   662 SRRDKLKEHIIKHHNSEVLTFQKTQRRKYKRQRMLAAASNIVNNPDALFRPITSDDAVSNWQATN 726

  Fly   560 DVAAIA---NDYSG 570
            |.:..:   |||.|
 Worm   727 DFSTYSPNPNDYGG 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grau	NP_788422.1	zf-AD	3..74	CDD:462262	7/32 (22%)
		C2H2 Zn finger	272..290	CDD:275368	5/19 (26%)
		COG5048	<296..453	CDD:227381	44/175 (25%)
		C2H2 Zn finger	298..318	CDD:275368	6/25 (24%)
		C2H2 Zn finger	329..349	CDD:275368	6/21 (29%)
		C2H2 Zn finger	359..409	CDD:275368	12/54 (22%)
		C2H2 Zn finger	360..378	CDD:275370	4/22 (18%)
		zf-C2H2_8	419..502	CDD:464935	26/88 (30%)
		C2H2 Zn finger	450..471	CDD:275368	6/22 (27%)
		C2H2 Zn finger	478..498	CDD:275368	6/19 (32%)
		C2H2 Zn finger	506..524	CDD:275368	3/17 (18%)
eor-1	NP_001367921.1	PHA03098	34..>229	CDD:222983	4/12 (33%)
		BTB_POZ_ZBTB_KLHL-like	41..118	CDD:349497
		C2H2 Zn finger	455..475	CDD:275368	4/21 (19%)
		C2H2 Zn finger	483..503	CDD:275368	6/21 (29%)
		C2H2 Zn finger	511..531	CDD:275368	5/22 (23%)
		C2H2 Zn finger	541..561	CDD:275368	5/19 (26%)
		C2H2 Zn finger	569..589	CDD:275368	7/19 (37%)
		C2H2 Zn finger	601..618	CDD:275368	5/16 (31%)
		C2H2 Zn finger	626..646	CDD:275368	6/19 (32%)
		zf-H2C2_2	638..663	CDD:463886	7/24 (29%)
		zf-H2C2_5	652..676	CDD:404746	5/23 (22%)
		C2H2 Zn finger	654..674	CDD:275368	3/19 (16%)