DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment e(y)2 and ENY2

DIOPT Version :9

Sequence 1:NP_524846.1 Gene:e(y)2 / 45848 FlyBaseID:FBgn0000618 Length:101 Species:Drosophila melanogaster
Sequence 2:NP_064574.1 Gene:ENY2 / 56943 HGNCID:24449 Length:101 Species:Homo sapiens


Alignment Length:84 Identity:41/84 - (48%)
Similarity:64/84 - (76%) Gaps:1/84 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 AVDQYTVLTGDRSKIKDLLCSRLTECGWRDEVRLMCRNILMEKGTNNSFTVEQLIAEVTPKARTL 70
            |::|..:.||:|.::|:||.::|.||||:|:::..|:.::.|||..: .||:.|:||:|||.|.|
Human    15 AINQKLIETGERERLKELLRAKLIECGWKDQLKAHCKEVIKEKGLEH-VTVDDLVAEITPKGRAL 78

  Fly    71 VPDAVKKELLMKIRTILTE 89
            |||:||||||.:|||.|.:
Human    79 VPDSVKKELLQRIRTFLAQ 97

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
e(y)2NP_524846.1 EnY2 6..87 CDD:287172 40/80 (50%)
ENY2NP_064574.1 EnY2 16..94 CDD:401971 38/78 (49%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165160348
Domainoid 1 1.000 93 1.000 Domainoid score I7582
eggNOG 1 0.900 - - E1_KOG4479
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 94 1.000 Inparanoid score I5077
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG54942
OrthoDB 1 1.010 - - D1538551at2759
OrthoFinder 1 1.000 - - FOG0004955
OrthoInspector 1 1.000 - - oto90922
orthoMCL 1 0.900 - - OOG6_103619
Panther 1 1.100 - - LDO PTHR12514
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1416
SonicParanoid 1 1.000 - - X5291
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1514.800

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