DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cpo and Rbpms2

DIOPT Version :9

Sequence 1:	NP_001014632.3	Gene:	cpo / 45840	FlyBaseID:	FBgn0263995	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	NP_082306.2	Gene:	Rbpms2 / 71973	MGIID:	1919223	Length:	206	Species:	Mus musculus

Alignment Length:	183	Identity:	94/183 - (51%)
Similarity:	113/183 - (61%)	Gaps:	36/183 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   438 EEEVRTLFVSGLPMDAKPRELYLLFRAYEGYEGSLLKVTSKNGKTASPVGFVTFHTRAGAEAAKQ 502
            |||||||||||||:|.||||||||||.::||||||:|:||:     .|||||.|.:||||||||.
Mouse    21 EEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTSR-----QPVGFVIFDSRAGAEAAKN 80

  Fly   503 DLQGVRFDPDMPQTIRLEFAKSNTKVSKPK----PQPNTATTASHPALMHPLTGH-----LGGPF 558
            .|.|:||||:.|||:||||||:|||::|.|    |.|    |:.||||...|...     :|...
Mouse    81 ALNGIRFDPENPQTLRLEFAKANTKMAKSKLIATPNP----TSVHPALGAHLIARDPYDLMGTAL 141

  Fly   559 FPGGPELW-HHPLAYSAAAAAELPGAAALQHATLVHPA----------LHPQV 600
            .|..||.| .:|| |:    .||  ..|:.|.|..:||          ||.||
Mouse   142 IPASPEAWAPYPL-YT----TEL--TPAISHTTFTYPAATAAAAAAATLHAQV 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cpo	NP_001014632.3	RRM	<428..>525	CDD:223796	62/86 (72%)
		RRM_cpo	441..523	CDD:241128	57/81 (70%)
		RRM_scw1_like	712..819	CDD:240691
Rbpms2	NP_082306.2	RRM_RBPMS2	24..99	CDD:241127	55/79 (70%)
Rbpms2	NP_082306.2	Important for homodimerization. /evidence=ECO:0000250\|UniProtKB:Q6ZRY4	35..45		8/9 (89%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	90	1.000	Domainoid score	I7758
eggNOG	1	0.900	-	-		E1_KOG1457
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002113
OrthoInspector	1	1.000	-	-		otm43941
orthoMCL	1	0.900	-	-		OOG6_104919
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3149
SonicParanoid	1	1.000	-	-		X1401
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.700