DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cpo and rbpms2a

DIOPT Version :9

Sequence 1:	NP_001014632.3	Gene:	cpo / 45840	FlyBaseID:	FBgn0263995	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	XP_021326148.1	Gene:	rbpms2a / 436682	ZFINID:	ZDB-GENE-040718-106	Length:	267	Species:	Danio rerio

Alignment Length:	245	Identity:	104/245 - (42%)
Similarity:	138/245 - (56%)	Gaps:	49/245 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   390 TSAVSDSNNNLNSSSSSNSNSNAIMENQMALAPLG------LSQSMDSVNTASNEEEVRTLFVSG 448
            |||:|.....|:|..|:::.::.:.....:.|.:|      ||..: ..::..:..:||||||||
Zfish    14 TSALSLPTVPLSSFLSTSTQTSLMCLRAYSTALIGQRSHCCLSAGV-CCHSGVSLFQVRTLFVSG 77

  Fly   449 LPMDAKPRELYLLFRAYEGYEGSLLKVTSKNGKTASPVGFVTFHTRAGAEAAKQDLQGVRFDPDM 513
            ||:|.||||||||||.::||||||:|:|||     .|||||||.:|:||||||..|.|:||||:.
Zfish    78 LPVDIKPRELYLLFRPFKGYEGSLIKLTSK-----QPVGFVTFDSRSGAEAAKNALNGIRFDPES 137

  Fly   514 PQTIRLEFAKSNTKVSKPK--PQPNTATTASHPALMHPLTG-HL---------GGPFFPGGPELW 566
            |||:||||||:|||::|.|  ..||       |:.:||..| |.         |....|..||.|
Zfish   138 PQTLRLEFAKANTKMAKSKLMATPN-------PSNLHPALGAHFIARDPYDLTGAALIPASPEAW 195

  Fly   567 -HHPLAYSAAAAAELPGAAALQHATLVHP-------ALHPQV---PVRSY 605
             .:|| |:......||      ||...:|       |||.||   |:|.|
Zfish   196 APYPL-YTTELTPGLP------HAAFTYPAAAAAAAALHAQVRDPPMRWY 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cpo	NP_001014632.3	RRM	<428..>525	CDD:223796	60/96 (63%)
		RRM_cpo	441..523	CDD:241128	58/81 (72%)
		RRM_scw1_like	712..819	CDD:240691
rbpms2a	XP_021326148.1	RRM_RBPMS2	70..145	CDD:241127	56/79 (71%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7580
eggNOG	1	0.900	-	-		E1_KOG1457
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002113
OrthoInspector	1	1.000	-	-		otm24756
orthoMCL	1	0.900	-	-		OOG6_104919
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3149
SonicParanoid	1	1.000	-	-		X1401
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.700