DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cpo and rbpms2b

DIOPT Version :9

Sequence 1:	NP_001014632.3	Gene:	cpo / 45840	FlyBaseID:	FBgn0263995	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	NP_956553.1	Gene:	rbpms2b / 393229	ZFINID:	ZDB-GENE-040426-741	Length:	200	Species:	Danio rerio

Alignment Length:	192	Identity:	98/192 - (51%)
Similarity:	112/192 - (58%)	Gaps:	37/192 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   425 LSQSMDSV--NTASNEEEVRTLFVSGLPMDAKPRELYLLFRAYEGYEGSLLKVTSKNGKTASPVG 487
            :|...||.  |..|.|||||||||||||.|.||||||||||.::||||||:|:|||     .|||
Zfish     1 MSVKSDSEPNNNVSLEEEVRTLFVSGLPTDIKPRELYLLFRPFKGYEGSLIKLTSK-----QPVG 60

  Fly   488 FVTFHTRAGAEAAKQDLQGVRFDPDMPQTIRLEFAKSNTKVSKPKPQPNTATTASHPAL------ 546
            ||||.:|:||||||..|.||||||:.|||:||||||:|||::|.|.......|..||||
Zfish    61 FVTFDSRSGAEAAKNALNGVRFDPENPQTLRLEFAKANTKMAKSKLMGTPNPTNIHPALGAHFIA 125

  Fly   547 --MHPLTGHLGGPFFPGGPELW---------------HHPLAYSAAAAAELPGAAALQHATL 591
              .:.||   |....|..||.|               |....|.|||||    |||..||.:
Zfish   126 RDPYDLT---GAALIPASPEAWSPYPLYTPELSPGLPHTAFTYPAAAAA----AAAALHAQM 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cpo	NP_001014632.3	RRM	<428..>525	CDD:223796	68/98 (69%)
		RRM_cpo	441..523	CDD:241128	59/81 (73%)
		RRM_scw1_like	712..819	CDD:240691
rbpms2b	NP_956553.1	RRM	<4..>83	CDD:223796	56/83 (67%)
rbpms2b	NP_956553.1	RRM_RBPMS2	19..94	CDD:241127	57/79 (72%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7580
eggNOG	1	0.900	-	-		E1_KOG1457
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002113
OrthoInspector	1	1.000	-	-		otm24756
orthoMCL	1	0.900	-	-		OOG6_104919
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1401
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.670