DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cpo and Rbpms

DIOPT Version :9

Sequence 1:	NP_001014632.3	Gene:	cpo / 45840	FlyBaseID:	FBgn0263995	Length:	962	Species:	Drosophila melanogaster
Sequence 2:	XP_006509097.1	Gene:	Rbpms / 19663	MGIID:	1334446	Length:	261	Species:	Mus musculus

Alignment Length:	185	Identity:	90/185 - (48%)
Similarity:	113/185 - (61%)	Gaps:	22/185 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   427 QSMDSV---NTASNEEEVRTLFVSGLPMDAKPRELYLLFRAYEGYEGSLLKVTSKNGKTASPVGF 488
            |:|.:|   |:..:..:||||||||||:|.||||||||||.::||||||:|:|||     .||||
Mouse    23 QNMLAVTGRNSRVSRCKVRTLFVSGLPLDIKPRELYLLFRPFKGYEGSLIKLTSK-----QPVGF 82

  Fly   489 VTFHTRAGAEAAKQDLQGVRFDPDMPQTIRLEFAKSNTKVSKPK---------PQPNTAT--TAS 542
            |:|.:|:.|||||..|.|:||||::|||:||||||:|||::|.|         |.|||..  .|.
Mouse    83 VSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLVGTPNPSTPLPNTVPQFIAR 147

  Fly   543 HPALMHP-LTGHLGGPFFPGGPELWHHPLAYSAAAAAELPGAAALQHATLVHPAL 596
            .|..:.| |.||..|...|.  .|....|....|||..|.|..|:......|||:
Mouse   148 EPYALDPSLRGHFPGLEVPA--VLLRLCLGCVMAAAICLVGINAVFTGGDCHPAV 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cpo	NP_001014632.3	RRM	<428..>525	CDD:223796	61/99 (62%)
		RRM_cpo	441..523	CDD:241128	56/81 (69%)
		RRM_scw1_like	712..819	CDD:240691
Rbpms	XP_006509097.1	RRM_RBPMS	40..115	CDD:241126	54/79 (68%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	90	1.000	Domainoid score	I7758
eggNOG	1	0.900	-	-		E1_KOG1457
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4385
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002113
OrthoInspector	1	1.000	-	-		otm43941
orthoMCL	1	0.900	-	-		OOG6_104919
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1401
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.620