Protein Alignment bur and Gmps

DIOPT Version :9

• Sequence 1: NP_001286120.1
• Gene: bur / 45830
• FlyBaseID: FBgn0000239
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: XP_038957944.1
• Gene: Gmps / 295088
• RGDID: 1310063
• Length: 734
• Species: Rattus norvegicus
• Alignment Length: 683
• Identity: 403/683 - (59%)
• Similarity: 520/683 - (76%)
• Gaps: 11/683 - (1%)

  Fly     8 GTAENGLRH--DKIVILDAGAQYGKVIDRKVRELFVETDILPLDTPAATIRNNGYRGIIISGGPN 70
            |..::|..|  ..:|||||||||||||||:||||||:::|.||:|||..|:..|:|.||||||||
  Rat    56 GDLKDGCHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETPAFAIKEQGFRAIIISGGPN 120

  Fly    71 SVYAEDAPSYDPDLFKLKIPMLGICYGMQLINKEFGGTVLKKDVREDGQQNIEIETSCPLFSRLS 135
            ||||||||.:||.:|.:..|:||||||||::||.|||||.||.|||||..||.::.:|.||..|.
  Rat   121 SVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHKKSVREDGVFNISMDNTCSLFRGLQ 185

  Fly   136 RTQSVLLTHGDSVERVGENLKIGGWSTNRIVTAIYNEVLRIYGVQFHPEVDLTINGKQMLSNFLY 200
            :.:.|||||||||::|.:..|:...|.| ||..|.||..::|||||||||.||.|||.:|.||||
  Rat   186 KEEIVLLTHGDSVDKVADGFKVVARSGN-IVAGIANESKKLYGVQFHPEVGLTENGKVILKNFLY 249

  Fly   201 EICELTPNFTMGSRKEECIRYIREKVGNNKVLLLVSGGVDSSVCAALLRRALYPHQIIAVHVDNG 265
            :|...:.|||:.:|:.||||.|:||||.:|||:|:||||||:||.|||.|||...|:||||:|||
  Rat   250 DIAGCSGNFTVQNRELECIREIKEKVGTSKVLVLLSGGVDSTVCTALLNRALNQDQVIAVHIDNG 314

  Fly   266 FMRKKESEKVERSLRDIGIDLIVRKEGYTFLKGTTQV-----KRPGQYSVVETPMLCQTYNPEEK 325
            ||||:||:.||.:|:.:||.:.|....::|..|||.:     .|..:..:.:|  |..|.:||||
  Rat   315 FMRKRESQSVEEALKKLGIQVKVINAAHSFYNGTTTLPISDEDRTPRKRISKT--LNMTTSPEEK 377

  Fly   326 RKIIGDIFVKVTNDVVAELKLKPEEVMLAQGTLRPDLIESASSMVSTNAETIKTHHNDTDLIREL 390
            ||||||.|||:.|:|:.|:.||||||.|||||||||||||||.:.|..||.||||||||:|||:|
  Rat   378 RKIIGDTFVKIANEVIGEMSLKPEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKL 442

  Fly   391 RNAGRVVEPLCDFHKDEVRDLGNDLGLPQELVERQPFPGPGLAIRVLCAEEAYMEKDYSETQVII 455
            |..|:|:|||.||||||||.||.:|.||:|||.|.|||||||||||:||||.|:.||:.||..|:
  Rat   443 REEGKVIEPLKDFHKDEVRILGRELDLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNIL 507

  Fly   456 RVIVDYKNKLQKNHALINRVTAATSEAEQKDLMRISSNSQIQATLLPIRSVGVQGDKRSYSYVVG 520
            :::.|:...::|.|.|:.||.|.|:|.:|:.||.|:|...:.|.||||::||||||.||||||.|
  Rat   508 KIVADFSASVKKPHTLLQRVKACTTEEDQEKLMEITSQHSLNAFLLPIKTVGVQGDCRSYSYVCG 572

  Fly   521 LSTSQEPNWQDLLFLAKIIPRILHNVNRVCYIFGEPVQYLVTDITHTTLNTVVLSQLRQADDIAN 585
            :|:..||:|:.|:|||::|||:.||:|||.||||.||:...||:|.|.|.|.|||.|||||..|:
  Rat   573 ISSKDEPDWESLIFLARLIPRMCHNINRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAH 637

  Fly   586 EIIMQAGLYRKISQMPVVLIPVHFDRDPINRTPSCRRSVVLRPFITNDFMTGVPAEPGSVQMPLQ 650
            .|:.::|...|||||||:|.|:||||||:.:.|||:||||:|.|||:||||||||.||: ::|::
  Rat   638 NILRESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGVPATPGN-EIPVE 701

  Fly   651 VLNQIVRDISKLDGISRVLYDLTAKPPGTTEWE 683
            |:.::|.:|.|:.||||::||||:|||||||||
  Rat   702 VVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bur	NP_001286120.1	guaA	16..683	CDD:234614	399/673 (59%)
		GATase1_GMP_Synthase	19..199	CDD:153213	112/179 (63%)
		GMP_synthase_C	230..682	CDD:238955	268/456 (59%)
Gmps	XP_038957944.1	guaA	69..734	CDD:234614	398/668 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354297
Domainoid	1	1.000	230	1.000	Domainoid score	I2375
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68367
Inparanoid	1	1.050	798	1.000	Inparanoid score	I479
OMA	1	1.010	-	-		QHG60613
OrthoDB	1	1.010	-	-		D302109at33208
OrthoFinder	1	1.000	-	-		FOG0004108
OrthoInspector	1	1.000	-	-		oto97198
orthoMCL	1	0.900	-	-		OOG6_100862
Panther	1	1.100	-	-	LDO	PTHR11922
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2849
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910