Protein Alignment bur and Gmps

DIOPT Version :10

• Sequence 1: NP_620114.3
• Gene: bur / 45830
• FlyBaseID: FBgn0000239
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: XP_011238380.1
• Gene: Gmps / 229363
• MGIID: 2448526
• Length: 745
• Species: Mus musculus
• Alignment Length: 683
• Identity: 403/683 - (59%)
• Similarity: 521/683 - (76%)
• Gaps: 11/683 - (1%)

  Fly     8 GTAENGLRH--DKIVILDAGAQYGKVIDRKVRELFVETDILPLDTPAATIRNNGYRGIIISGGPN 70
            |..::|..|  ..:|||||||||||||||:||||||:::|.||:|||..|:..|:|.||||||||
Mouse    67 GDLKDGSHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETPAFAIKEQGFRAIIISGGPN 131

  Fly    71 SVYAEDAPSYDPDLFKLKIPMLGICYGMQLINKEFGGTVLKKDVREDGQQNIEIETSCPLFSRLS 135
            ||||||||.:||.:|.:..|:||||||||::||.|||||.||.|||||..||.::.:|.||..|.
Mouse   132 SVYAEDAPWFDPAIFTIGKPILGICYGMQMMNKVFGGTVHKKSVREDGVFNISMDNTCSLFRGLQ 196

  Fly   136 RTQSVLLTHGDSVERVGENLKIGGWSTNRIVTAIYNEVLRIYGVQFHPEVDLTINGKQMLSNFLY 200
            :.:.|||||||||::|.:..|:...|.| ||..|.||..::|||||||||.||.|||.:|.||||
Mouse   197 KEEIVLLTHGDSVDKVADGFKVVARSGN-IVAGIANESKKLYGVQFHPEVGLTENGKVILKNFLY 260

  Fly   201 EICELTPNFTMGSRKEECIRYIREKVGNNKVLLLVSGGVDSSVCAALLRRALYPHQIIAVHVDNG 265
            :|...:.|||:.:|:.||||.|:||||.:|||:|:||||||:||.|||.|||...|:||||:|||
Mouse   261 DIAGCSGNFTVQNRELECIREIKEKVGTSKVLVLLSGGVDSTVCTALLNRALNQDQVIAVHIDNG 325

  Fly   266 FMRKKESEKVERSLRDIGIDLIVRKEGYTFLKGTTQV-----KRPGQYSVVETPMLCQTYNPEEK 325
            ||||:||:.||.:|:.:||.:.|....::|..|||.:     .|..:..:.:|  |..|.:||||
Mouse   326 FMRKRESQSVEEALKKLGIQVKVINAAHSFYNGTTTLPISDEDRTPRKRISKT--LNMTTSPEEK 388

  Fly   326 RKIIGDIFVKVTNDVVAELKLKPEEVMLAQGTLRPDLIESASSMVSTNAETIKTHHNDTDLIREL 390
            ||||||.|||:.|:|:.|:.||||||.|||||||||||||||.:.|..||.||||||||:|||:|
Mouse   389 RKIIGDTFVKIANEVIGEMSLKPEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKL 453

  Fly   391 RNAGRVVEPLCDFHKDEVRDLGNDLGLPQELVERQPFPGPGLAIRVLCAEEAYMEKDYSETQVII 455
            |..|:|:|||.||||||||.||.:|.||:|||.|.|||||||||||:||||.|:.||:.||..|:
Mouse   454 REEGKVIEPLKDFHKDEVRILGRELDLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNIL 518

  Fly   456 RVIVDYKNKLQKNHALINRVTAATSEAEQKDLMRISSNSQIQATLLPIRSVGVQGDKRSYSYVVG 520
            :::.|:...::|.|.|:.||.|.|:|.:|:.||:|:|...:.|.||||::||||||.||||||.|
Mouse   519 KIVADFSASVKKPHTLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCG 583

  Fly   521 LSTSQEPNWQDLLFLAKIIPRILHNVNRVCYIFGEPVQYLVTDITHTTLNTVVLSQLRQADDIAN 585
            :|:..||:|:.|:|||::|||:.||:|||.||||.||:...||:|.|.|.|.|||.|||||..|:
Mouse   584 ISSKDEPDWESLIFLARLIPRMCHNINRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAH 648

  Fly   586 EIIMQAGLYRKISQMPVVLIPVHFDRDPINRTPSCRRSVVLRPFITNDFMTGVPAEPGSVQMPLQ 650
            .|:.::|...|||||||:|.|:||||||:.:.|||:||||:|.|||:||||||||.||: ::|::
Mouse   649 NILRESGFAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGVPATPGN-EIPVE 712

  Fly   651 VLNQIVRDISKLDGISRVLYDLTAKPPGTTEWE 683
            |:.::|.:|.|:.||||::||||:|||||||||
Mouse   713 VVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bur	NP_620114.3	guaA	16..683	CDD:234614	399/673 (59%)
		GMP_synt_C	494..551	CDD:425963	34/56 (61%)
Gmps	XP_011238380.1	guaA	80..745	CDD:234614	398/668 (60%)