Protein Alignment bur and gmps-1

DIOPT Version :9

• Sequence 1: NP_001286120.1
• Gene: bur / 45830
• FlyBaseID: FBgn0000239
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: NP_001022257.2
• Gene: gmps-1 / 174672
• WormBaseID: WBGene00010912
• Length: 745
• Species: Caenorhabditis elegans
• Alignment Length: 706
• Identity: 347/706 - (49%)
• Similarity: 469/706 - (66%)
• Gaps: 58/706 - (8%)

  Fly    17 DKIVILDAGAQYGKVIDRKVRELFVETDILPLDTPAAT-IRNNGYRGIIISGGPNSVYAEDAPSY 80
            ::|.|||.||||||||||:||||.|::::.||:|.|.| |...|::|||||||||||:..:|||.
 Worm    59 ERIAILDFGAQYGKVIDRRVRELLVQSEMFPLNTTARTLIELGGFKGIIISGGPNSVFEPEAPSI 123

  Fly    81 DPDLFKLKIPMLGICYGMQLINKEFGGTVLKKDVREDGQQNIEIETSCPLFSRLSRTQSVLLTHG 145
            ||::|...:|:||||||.||:||..||||.::.:||||...|:::||..||:.|.:|::||||||
 Worm   124 DPEIFTCGLPVLGICYGFQLMNKLNGGTVTREHIREDGACEIQVDTSVHLFNGLHKTETVLLTHG 188

  Fly   146 DSVER--VGENLKIGGWSTNRIVTAIYNEVLRIYGVQFHPEVDLTINGKQMLSNFLYEICELTPN 208
            |||..  |..:.|:...|.:. |..|.||..::||||||||||||.||.:|..|||:::.....|
 Worm   189 DSVSEATVAPDFKVMAKSGHH-VAGICNENRKLYGVQFHPEVDLTTNGTKMFENFLFKVVGCCGN 252

  Fly   209 FTMGSRKEECIRYIREKVGNNKVLLLVSGGVDSSVCAALLRRALYPHQIIAVHVDNGFMRKKESE 273
            ||:.:|::.||..|...||:.|||::|||||||:||||||||||.|:::.|:|:||||||.:||:
 Worm   253 FTIQNREQSCISEINSIVGDKKVLVMVSGGVDSAVCAALLRRALGPNRVTAIHIDNGFMRHEESD 317

  Fly   274 KVERSLRDIGIDLIVRKEGY-TFLKGTTQVKRPGQYSVVETPMLCQTYNPEEKRKIIGDIFVKVT 337
            .||:||  ..:||.:.:..: |..:.:|:..:.|:.::.|    |.  :||.||||||:.|::|.
 Worm   318 AVEKSL--AALDLPIHRYNFGTTFRSSTEHCKDGEVALDE----CD--DPEMKRKIIGNTFIRVK 374

  Fly   338 NDVVAELKLKPEEVMLAQGTLRPDLIESASSMVSTNAETIKTHHNDTDLIRELRNAGRVVEPLCD 402
            :.::.:|.:..:|..|||||||||||||||::.|.:|:|||||||||.|:||||..|:|||||.|
 Worm   375 DVIMKDLNINHDEYFLAQGTLRPDLIESASALASGHADTIKTHHNDTFLVRELRKLGKVVEPLKD 439

  Fly   403 FHKDEVRDLGNDLGLPQELVERQPFPGPGLAIRVLCAEEAYMEKDYSETQV-------IIRVIVD 460
            |||||||:||.|||||:.:|:|.||||||||||:|||.:...|..::....       ||.|...
 Worm   440 FHKDEVRELGKDLGLPESIVQRHPFPGPGLAIRILCASDKRPELMFNGPMYNGDVQGRIIDVTEQ 504

  Fly   461 YKNK-----------LQKNHALINRVTAATSE-----AEQKDLMRISSNSQIQATLLPIRSVGVQ 509
            :.|.           ||...|. |.|..:.||     |||:..       ||.|.:|||::||||
 Worm   505 FLNSAINPSQGIYEHLQFEQAR-NNVLLSLSERDRQLAEQQTF-------QISAHILPIKTVGVQ 561

  Fly   510 GDKRSYSYVVGLSTSQEP-NWQDLLFLAKIIPRILHNVNRVCYIFGEPVQYLVTDITHTTLNTVV 573
            ||.|||||.|.|||.|.| .|:.|...|.:||::.|.||||.|.||..:::.:.|:|.|.|...:
 Worm   562 GDARSYSYAVALSTEQRPIPWKLLFAYASVIPKLFHGVNRVVYAFGSKIEFSIEDLTRTYLVPHI 626

  Fly   574 LSQLRQADDIANEII----------MQAGLYRKISQMPVVLIPVHFDRDPINRTPSCRRSVVLRP 628
            :::|:.||.|||.|:          ....:..||.||||||:||.||||. :...|.|.|:||||
 Worm   627 VTKLQMADHIANNILFGRVAASDGTQLPNVGHKIQQMPVVLLPVDFDRDR-DMIGSYRHSIVLRP 690

  Fly   629 FITNDFMTGVPAEPGSVQMPLQVLNQIVRDI-SKLDGISRVLYDLTAKPPGTTEWE 683
            |:|:|||||..|.|| |.:|.:.|.::.:.| :.:.||||||.|:|.|||||||||
 Worm   691 FVTSDFMTGQAAIPG-VHLPEETLIEMDKAIRTNVLGISRVLLDMTCKPPGTTEWE 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bur	NP_001286120.1	guaA	16..683	CDD:234614	345/704 (49%)
		GATase1_GMP_Synthase	19..199	CDD:153213	101/182 (55%)
		GMP_synthase_C	230..682	CDD:238955	232/487 (48%)
gmps-1	NP_001022257.2	guaA	59..611	CDD:234614	284/568 (50%)
		GATase1_GMP_Synthase	61..243	CDD:153213	101/182 (55%)
		GMP_synthase_C	274..744	CDD:238955	232/487 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167699
Domainoid	1	1.000	197	1.000	Domainoid score	I1823
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68367
Inparanoid	1	1.050	607	1.000	Inparanoid score	I499
Isobase	1	0.950	-	0	Normalized mean entropy	S1429
OMA	1	1.010	-	-		QHG60613
OrthoDB	1	1.010	-	-		D302109at33208
OrthoFinder	1	1.000	-	-		FOG0004108
OrthoInspector	1	1.000	-	-		oto17553
orthoMCL	1	0.900	-	-		OOG6_100862
Panther	1	1.100	-	-	LDO	PTHR11922
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R534
SonicParanoid	1	1.000	-	-		X2849
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.890