Protein Alignment bur and gmps

DIOPT Version :9

• Sequence 1: NP_001286120.1
• Gene: bur / 45830
• FlyBaseID: FBgn0000239
• Length: 683
• Species: Drosophila melanogaster
• Sequence 2: XP_012818897.1
• Gene: gmps / 100494801
• XenbaseID: XB-GENE-950696
• Length: 703
• Species: Xenopus tropicalis
• Alignment Length: 670
• Identity: 395/670 - (58%)
• Similarity: 510/670 - (76%)
• Gaps: 9/670 - (1%)

  Fly    19 IVILDAGAQYGKVIDRKVRELFVETDILPLDTPAATIRNNGYRGIIISGGPNSVYAEDAPSYDPD 83
            :|||||||||||||||::||.||:::|.||:|||..||..|:|.||||||||||||||||.:|..
 Frog    38 VVILDAGAQYGKVIDRRIREFFVQSEIFPLETPAFAIREQGFRAIIISGGPNSVYAEDAPWFDSA 102

  Fly    84 LFKLKIPMLGICYGMQLINKEFGGTVLKKDVREDGQQNIEIETSCPLFSRLSRTQSVLLTHGDSV 148
            :|.:..|:||||||||::||.|||||.||:|||||...|.|:.:|.||..|.:.:.|||||||||
 Frog   103 IFAIGKPVLGICYGMQMMNKVFGGTVHKKNVREDGVFPITIDNTCSLFRGLQKEEVVLLTHGDSV 167

  Fly   149 ERVGENLKIGGWSTNRIVTAIYNEVLRIYGVQFHPEVDLTINGKQMLSNFLYEICELTPNFTMGS 213
            ::|.:..||...|.| ||..|.||..::|||||||||.||.||:.||.||||:|...:..||:.:
 Frog   168 DKVADGFKIVAQSGN-IVAGIANEAKKLYGVQFHPEVGLTENGRVMLKNFLYDIAGCSGTFTVQN 231

  Fly   214 RKEECIRYIREKVGNNKVLLLVSGGVDSSVCAALLRRALYPHQIIAVHVDNGFMRKKESEKVERS 278
            |:.||||.|:||||::|||:|:||||||:||.|||.:||...|:||||:|||||||:||:.||.:
 Frog   232 REVECIREIKEKVGSSKVLVLLSGGVDSTVCTALLNKALNQDQVIAVHIDNGFMRKRESQSVEEA 296

  Fly   279 LRDIGIDLIVRKEGYTFLKGTTQV-----KRPGQYSVVETPMLCQTYNPEEKRKIIGDIFVKVTN 338
            |:.:||.:.|....::|..|||.:     .|..:..:.:|  |..|.|||||||||||.|||:.|
 Frog   297 LKKLGIQVKVVNAAHSFYNGTTTLPISDEDRTPRKRISKT--LNMTTNPEEKRKIIGDTFVKIAN 359

  Fly   339 DVVAELKLKPEEVMLAQGTLRPDLIESASSMVSTNAETIKTHHNDTDLIRELRNAGRVVEPLCDF 403
            :|:.|:.|.||||.|||||||||||||||.:.|..||.||||||||:|||:||..|:|:|||.||
 Frog   360 EVIGEMNLNPEEVFLAQGTLRPDLIESASLIASVKAEVIKTHHNDTELIRKLREEGKVIEPLKDF 424

  Fly   404 HKDEVRDLGNDLGLPQELVERQPFPGPGLAIRVLCAEEAYMEKDYSETQVIIRVIVDYKNKLQKN 468
            ||||||.||.:||||:|||.|.|||||||||||:||||.|:.||::||..|::::.||...::|.
 Frog   425 HKDEVRVLGRELGLPEELVCRHPFPGPGLAIRVICAEEPYVCKDFAETNNILKIVADYSASVKKP 489

  Fly   469 HALINRVTAATSEAEQKDLMRISSNSQIQATLLPIRSVGVQGDKRSYSYVVGLSTSQEPNWQDLL 533
            |.|:.||.|.|||.:|..||:|:|...:.|.||||::||||||.||||||.|:|....|:|:.|:
 Frog   490 HTLLQRVKACTSEEDQDKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISCKDAPHWESLM 554

  Fly   534 FLAKIIPRILHNVNRVCYIFGEPVQYLVTDITHTTLNTVVLSQLRQADDIANEIIMQAGLYRKIS 598
            :||::|||:.||:|||.|:||.||:...||:|.|.|.|.|||.|||||..|:.|:.::|...|||
 Frog   555 YLARLIPRMCHNINRVVYVFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILRESGFAGKIS 619

  Fly   599 QMPVVLIPVHFDRDPINRTPSCRRSVVLRPFITNDFMTGVPAEPGSVQMPLQVLNQIVRDISKLD 663
            |||::|.|:||||||:.:.|||:||||:|.|||:|||||:.|.||: ::|.:|:.::|.:|.|:.
 Frog   620 QMPIILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIAATPGN-EIPEEVVLKMVTEIKKIP 683

  Fly   664 GISRVLYDLTAKPPGTTEWE 683
            |||||:||||:|||||||||
 Frog   684 GISRVMYDLTSKPPGTTEWE 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bur	NP_001286120.1	guaA	16..683	CDD:234614	393/668 (59%)
		GATase1_GMP_Synthase	19..199	CDD:153213	111/179 (62%)
		GMP_synthase_C	230..682	CDD:238955	265/456 (58%)
gmps	XP_012818897.1	guaA	37..703	CDD:234614	393/668 (59%)
		GATase1_GMP_Synthase	38..217	CDD:153213	111/179 (62%)
		GMP_synthase_C	248..702	CDD:238955	265/456 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	235	1.000	Domainoid score	I2318
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68367
Inparanoid	1	1.050	784	1.000	Inparanoid score	I513
OMA	1	1.010	-	-		QHG60613
OrthoDB	1	1.010	-	-		D302109at33208
OrthoFinder	1	1.000	-	-		FOG0004108
OrthoInspector	1	1.000	-	-		oto103888
Panther	1	1.100	-	-	LDO	PTHR11922
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2849
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080