DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bic and BTF3L4

DIOPT Version :9

Sequence 1:	NP_476853.1	Gene:	bic / 45827	FlyBaseID:	FBgn0000181	Length:	169	Species:	Drosophila melanogaster
Sequence 2:	NP_689478.1	Gene:	BTF3L4 / 91408	HGNCID:	30547	Length:	158	Species:	Homo sapiens

Alignment Length:	153	Identity:	103/153 - (67%)
Similarity:	115/153 - (75%)	Gaps:	0/153 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNAEKLKKLQAQVRIGGKGTPRRKKKIVHSTPATDDKKLQSSLKKLSVNTIPGIEEVNIIKNDGT 65
            ||.|||.|||||||||||||.|||||:||.|...||||||||||||:||.|.||||||:||:|||
Human     1 MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGT 65

  Fly    66 VIHFNNPKAQASLPTNTFAITGHGENKTITEMVPGILTQLGPQDINQLKKLATEIASKSGAGGAA 130
            ||||||||.||||..||||||||.|.|.||||:||||:|||...:..|:|||.:...:.....|.
Human    66 VIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAP 130

  Fly   131 GSSAADAGDDDVPDLVENFEEVA 153
            .....|..|||||||||||:|.:
Human   131 KPEDIDEEDDDVPDLVENFDEAS 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bic	NP_476853.1	NAC	38..90	CDD:280093	43/51 (84%)
BTF3L4	NP_689478.1	NAC_BTF3	4..120	CDD:409234	87/115 (76%)
BTF3L4	NP_689478.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	122..158		14/32 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159255
Domainoid	1	1.000	95	1.000	Domainoid score	I7416
eggNOG	1	0.900	-	-		E1_KOG2240
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	200	1.000	Inparanoid score	I3781
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55040
OrthoDB	1	1.010	-	-		D1435264at2759
OrthoFinder	1	1.000	-	-		FOG0000935
OrthoInspector	1	1.000	-	-		mtm8606
orthoMCL	1	0.900	-	-		OOG6_101091
Panther	1	1.100	-	-	LDO	PTHR10351
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R790
SonicParanoid	1	1.000	-	-		X613
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800