DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bic and BTF3

DIOPT Version :9

Sequence 1:	NP_476853.1	Gene:	bic / 45827	FlyBaseID:	FBgn0000181	Length:	169	Species:	Drosophila melanogaster
Sequence 2:	NP_001032726.1	Gene:	BTF3 / 689	HGNCID:	1125	Length:	206	Species:	Homo sapiens

Alignment Length:	153	Identity:	97/153 - (63%)
Similarity:	109/153 - (71%)	Gaps:	1/153 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNAEKLKKLQAQVRIGGKGTPRRKKKIVHSTPATDDKKLQSSLKKLSVNTIPGIEEVNIIKNDGT 65
            ||.|||.|||||||||||||.|||||:||.|...||||||.|||||.||.|.||||||:..|.||
Human    50 MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGT 114

  Fly    66 VIHFNNPKAQASLPTNTFAITGHGENKTITEMVPGILTQLGPQDINQLKKLATEIASKSGAGGAA 130
            ||||||||.||||..|||.||||.|.|.:|||:|.||.|||...:..|::|| |...|....|.|
Human   115 VIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLA-EALPKQSVDGKA 178

  Fly   131 GSSAADAGDDDVPDLVENFEEVA 153
            ..:..:..||:||||||||:|.:
Human   179 PLATGEDDDDEVPDLVENFDEAS 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bic	NP_476853.1	NAC	38..90	CDD:280093	39/51 (76%)
BTF3	NP_001032726.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
		NAC	87..140	CDD:376630	39/52 (75%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	170..206		14/32 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	57	1.000	Domainoid score	I10888
eggNOG	1	0.900	-	-		E1_KOG2240
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37453
Inparanoid	1	1.050	200	1.000	Inparanoid score	I3781
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55040
OrthoDB	1	1.010	-	-		D1435264at2759
OrthoFinder	1	1.000	-	-		FOG0000935
OrthoInspector	1	1.000	-	-		mtm8606
orthoMCL	1	0.900	-	-		OOG6_101091
Panther	1	1.100	-	-	O	PTHR10351
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R790
SonicParanoid	1	1.000	-	-		X613
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.870