DRSC/TRiP Functional Genomics Resources

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Protein Alignment bel and PRP5

DIOPT Version :10

Sequence 1:NP_001262379.1 Gene:bel / 45826 FlyBaseID:FBgn0263231 Length:801 Species:Drosophila melanogaster
Sequence 2:NP_009796.1 Gene:PRP5 / 852539 SGDID:S000000441 Length:849 Species:Saccharomyces cerevisiae


Alignment Length:483 Identity:145/483 - (30%)
Similarity:238/483 - (49%) Gaps:67/483 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   279 EDIPVEATGQNVPPNITSFDDVQL-TEIIRNNVALARYDKPTPVQKHAIPIIINGRDLMACAQTG 342
            ::|.::.||  .|..:|.:..:.| |:.:........:...||:|..|:|.|::|||::..::||
Yeast   241 DNIKIKGTG--CPKPVTKWSQLGLSTDTMVLITEKLHFGSLTPIQSQALPAIMSGRDVIGISKTG 303

  Fly   343 SGKTAAFLVPILNQMYELGHVPPPQSTRQYSRRKQYPLGLVLAPTRELATQIFEEAKKFAYR-SR 406
            ||||.::|:|:|.|:         ::.|..|:.:..|:||:||||||||.||.||..||... :.
Yeast   304 SGKTISYLLPLLRQV---------KAQRPLSKHETGPMGLILAPTRELALQIHEEVTKFTEADTS 359

  Fly   407 MRPAVLYGGNNTSEQMRELDRGCHLIVATPGRLEDMIT--RGK-VGLENIRFLVLDEADRMLDMG 468
            :|.....||:...:|:.:|.||..::||||||..|::|  .|| :..:.|.|:|:|||||:.|:|
Yeast   360 IRSVCCTGGSEMKKQITDLKRGTEIVVATPGRFIDILTLNDGKLLSTKRITFVVMDEADRLFDLG 424

  Fly   469 FEPQIRRIVEQLNMPPTGQRQTLMFSATFPKQIQELASDFLSNYIFLAVGRVGSTSENITQTILW 533
            |||||.:|::.:.    ..:|.::||||||.:::..|...|.:.|.:.:...|..:||:.|....
Yeast   425 FEPQITQIMKTVR----PDKQCVLFSATFPNKLRSFAVRVLHSPISITINSKGMVNENVKQKFRI 485

  Fly   534 VYEPD-----------KRSYLLDLLSSIRDGPE---YTKDSLTLIFVETKKGADSLEEFLYQCNH 584
            .:..|           :||...|.:.|..||..   ...|:..:|||.::...|.:.:.|.....
Yeast   486 CHSEDEKFDNLVQLIHERSEFFDEVQSENDGQSSDVEEVDAKAIIFVSSQNICDFISKKLLNAGI 550

  Fly   585 PVTSIHGDRTQKEREEALRCFRSGDCPILVATAVAARGLDIPHVKHVINFDLPSDVEEYVHRIGR 649
            ...:||..:..:||...|..|:.....||:.|.|.:|||::|.|..||.::......:|||..||
Yeast   551 VTCAIHAGKPYQERLMNLEKFKREKNSILLCTEVLSRGLNVPEVSLVIIYNAVKTFAQYVHTTGR 615

  Fly   650 TGRMGNLGVATSFFNEKNRNICSDLLELLIETK----QEIPSF-------MEDMSSDRGHGGAKR 703
            |.|....|.|.:..      :..:|....|.:|    :||.:.       :::||:         
Yeast   616 TARGSRSGTAITLL------LHDELSGAYILSKAMRDEEIKALDPLQAKELQEMSA--------- 665

  Fly   704 AGRGGGGRYGGGFGSRDYRQSSGGGGGG 731
                   ::..|.....:|.|.|.||.|
Yeast   666 -------KFESGMKKGKFRLSKGFGGKG 686

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
belNP_001262379.1 DEADc_DDX3 275..522 CDD:350809 88/247 (36%)
SF2_C_DEAD 527..663 CDD:350174 40/149 (27%)
PRP5NP_009796.1 DEADc_DDX46 244..468 CDD:350711 87/238 (37%)
SrmB 255..707 CDD:440279 141/467 (30%)
KH-I_PRP5_like 749..837 CDD:411902
Blue background indicates that the domain is not in the aligned region.

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