Protein Alignment bel and PRP28

DIOPT Version :10

• Sequence 1: NP_001262379.1
• Gene: bel / 45826
• FlyBaseID: FBgn0263231
• Length: 801
• Species: Drosophila melanogaster
• Sequence 2: NP_010529.3
• Gene: PRP28 / 851830
• SGDID: S000002651
• Length: 588
• Species: Saccharomyces cerevisiae
• Alignment Length: 542
• Identity: 165/542 - (30%)
• Similarity: 271/542 - (50%)
• Gaps: 75/542 - (13%)

  Fly   176 GSGSNLNEQTAEDGQAQQQQQPRNDRWQEPER---PAGFDGSEGGQSAGGNRS---YN------- 227
            |...|.:.:.::.....:|::.:.:|.:|.|.   |...|.::.......:|.   :|
Yeast    19 GLDENTSGKISKPRFLNKQERSKQERLKENEESLTPTQSDSAKVEIKKVNSRDDSFFNETNDKKR 83

  Fly   228 NRGERGGGGYNSRWKEGGGSNVDYTKLGARDERLEVELFGVGNTGIN------FDKY-------- 278
            |..::.|..::..|.|...:...|..:.:   ...::|...|.|..|      ..|:
Yeast    84 NPSKQNGSKFHFSWNESEDTLSGYDPIVS---TRAIDLLWKGKTPKNAAESSYMGKHWTEKSLHE 145

  Fly   279 ----------EDIPVEATGQNVPPNITSFDDVQL--TEIIRNNVALARYDKPTPVQKHAIPIIIN 331
                      ||..:...|..|...:.:::::.:  .:::|..:...|:..|||:|:..||.:.|
Yeast   146 MNERDWRILKEDYAIVTKGGTVENPLRNWEELNIIPRDLLRVIIQELRFPSPTPIQRITIPNVCN 210

  Fly   332 ---GRDLMACAQTGSGKTAAFLVPILNQMYELGHVPP-PQSTRQYSRRKQYPLGLVLAPTRELAT 392
               .||.:..|.||||||.||::|||.:|   ...|| |.|.:....    |..|:|||||||..
Yeast   211 MKQYRDFLGVASTGSGKTLAFVIPILIKM---SRSPPRPPSLKIIDG----PKALILAPTRELVQ 268

  Fly   393 QIFEEAKKFA--------YRSRMRPAVLYGGNNTSEQMRELDRGCHLIVATPGRLEDMITRGKVG 449
            ||.:|.:|..        |..::...|  ||::..|....|..||.::|||||||.|.:....:.
Yeast   269 QIQKETQKVTKIWSKESNYDCKVISIV--GGHSLEEISFSLSEGCDILVATPGRLIDSLENHLLV 331

  Fly   450 LENIRFLVLDEADRMLDMGFEPQIRRIVEQ--LNMPPTGQRQTLMFSATFPKQIQELASDFLSNY 512
            ::.:..|||||||:|:|:|||.|:..|:.:  :|......||||||:||....|:::|:.::...
Yeast   332 MKQVETLVLDEADKMIDLGFEDQVTNILTKVDINADSAVNRQTLMFTATMTPVIEKIAAGYMQKP 396

  Fly   513 IFLAVGRVGSTSENITQTILWVYEPDKRSYLLDLLSSIRDGPEYTK-DSLTLIFVETKKGADSL- 575
            ::..:| |.:.||.:.|.::...:.|:     |....::  |...| |...:||:..|:.||.|
Yeast   397 VYATIG-VETGSEPLIQQVVEYADNDE-----DKFKKLK--PIVAKYDPPIIIFINYKQTADWLA 453

  Fly   576 EEFLYQCNHPVTSIHGDRTQKEREEALRCFRSGDCPILVATAVAARGLDIPHVKHVINFDLPSDV 640
            |:|..:.|..||.:||.::|::||.:|:.||:....|::||.|||||||||:|..|:||.:...:
Yeast   454 EKFQKETNMKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQISKKM 518

  Fly   641 EEYVHRIGRTGRMGNLGVATSF 662
            ::|:||||||||..|.|.|.||
Yeast   519 DDYIHRIGRTGRAANEGTAVSF 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bel	NP_001262379.1	DEADc_DDX3	275..522	CDD:350809	89/280 (32%)
		SF2_C_DEAD	527..663	CDD:350174	55/138 (40%)
PRP28	NP_010529.3	SrmB	175..559	CDD:440279	141/383 (37%)