DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bel and pit

DIOPT Version :9

Sequence 1:	NP_001262379.1	Gene:	bel / 45826	FlyBaseID:	FBgn0263231	Length:	801	Species:	Drosophila melanogaster
Sequence 2:	NP_001287459.1	Gene:	pit / 42595	FlyBaseID:	FBgn0266581	Length:	680	Species:	Drosophila melanogaster

Alignment Length:	451	Identity:	131/451 - (29%)
Similarity:	219/451 - (48%)	Gaps:	79/451 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   258 DERLEVELFGVGNTGINFDKYED--------------IPVEATGQNVPPNITSFDDVQLTEIIRN 308
            ||..||:...|.:...:.|:.||              :|.::..||..|   :.||...|  :.:
  Fly   113 DEVAEVDEEDVDSGSEDDDQQEDEDEEEPVPAKKTKLLPNKSKAQNGKP---AKDDEPFT--VES 172

  Fly   309 NVALARY----------------------------DKPTPVQKHAIPIIINGRDLMACAQTGSGK 345
            ::|...|                            .:.|.:|..::..::.||||:..|||||||
  Fly   173 SLAALDYRDSDDRSFASLKGAVSEATLRAIKEMGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGK 237

  Fly   346 TAAFLVPILNQMYELGHVPPPQSTRQYSRRKQYPLG-LVLAPTRELATQIFEEAKKFAYRSRMRP 409
            |.|||:|.:..:.:|..:|            :...| ::::|||||:.|.|...|:.........
  Fly   238 TLAFLIPAVELINKLRFMP------------RNGTGVIIISPTRELSMQTFGVLKELMAHHHHTY 290

  Fly   410 AVLYGGNNTSEQMRELDRGCHLIVATPGRLEDMITRGKVGL-ENIRFLVLDEADRMLDMGFEPQI 473
            .::.||:|...:..:|.:|.:::|||||||.|.:......| :|::.|::||.||:|::|||.::
  Fly   291 GLVMGGSNRQVESEKLGKGINILVATPGRLLDHLQNSPDFLYKNLQCLIIDEVDRILEIGFEEEL 355

  Fly   474 RRIVEQLNMPPTGQRQTLMFSATFPKQIQELASDFLSN---YIFLAVGRVGSTSENITQTILWVY 535
            ::|:   |:.|. :|||::||||...:|:.|:...|.:   |:.:...:..:|.:.:.|..: |.
  Fly   356 KQII---NLLPK-RRQTMLFSATQTARIEALSKLALKSEPIYVGVHDNQDTATVDGLEQGYI-VC 415

  Fly   536 EPDKRSYLLDLLSSIRDGPEYTKDSLTLIFVETKKGADSLEEFLYQCNHPVTSIHGDRTQKEREE 600
            ..:||  ||.|.:.::.    .:....::|..:........|.....:.|||||||.:.|.:|..
  Fly   416 PSEKR--LLVLFTFLKK----NRKKKVMVFFSSCMSVKYHHELFNYIDLPVTSIHGKQKQTKRTT 474

  Fly   601 ALRCFRSGDCPILVATAVAARGLDIPHVKHVINFDLPSDVEEYVHRIGRTGRMGNLGVATS 661
            ....|.:.:..||:.|.|||||||||.|..::.:|.|.|..||:||:|||.|    |..||
  Fly   475 TFFQFCNAESGILLCTDVAARGLDIPQVDWIVQYDPPDDPREYIHRVGRTAR----GSGTS 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bel	NP_001262379.1	DEADc	297..516	CDD:238167	72/251 (29%)
		DEXDc	315..529	CDD:214692	69/246 (28%)
		Helicase_C	538..654	CDD:278689	41/115 (36%)
pit	NP_001287459.1	SrmB	186..677	CDD:223587	114/373 (31%)
		DEADc	187..394	CDD:238167	66/222 (30%)
		HELICc	408..537	CDD:238034	46/135 (34%)
		DUF4217	569..627	CDD:290667
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451570
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840