DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bel and abs

DIOPT Version :9

Sequence 1:	NP_001262379.1	Gene:	bel / 45826	FlyBaseID:	FBgn0263231	Length:	801	Species:	Drosophila melanogaster
Sequence 2:	NP_524220.1	Gene:	abs / 40530	FlyBaseID:	FBgn0015331	Length:	619	Species:	Drosophila melanogaster

Alignment Length:	578	Identity:	198/578 - (34%)
Similarity:	291/578 - (50%)	Gaps:	96/578 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 QPRNDRWQEPERPAGFDGSEGGQSAGGNRSYNNRGERGGGGYN-------SRWKEGGGSNVDYTK 253
            ||::....|.|     |.|:|....          |..|..||       :..|:    ..:..|
  Fly    53 QPKSSSENENE-----DDSQGAHDV----------ETWGRKYNISLLDQHTELKK----IAEAKK 98

  Fly   254 LGARDERLEVE------------LFGVGN--TGINFD----------KY-------------EDI 281
            |.|.:::|..|            |.||..  .||.::          :|             .::
  Fly    99 LSAVEKQLREEEKIMESIAQQKALMGVAELAKGIQYEQPIKTAWKPPRYIREMSEEEREAVRHEL 163

  Fly   282 PVEATGQNVPPNITSFDDVQLTEIIRNNVALARYDKPTPVQKHAIPIIINGRDLMACAQTGSGKT 346
            .:...|:...|.|.||.:::..:.|.|.:|......|||:|...:|.::.||||:..|.||||||
  Fly   164 RILVEGETPSPPIRSFREMKFPKGILNGLAAKGIKNPTPIQVQGLPTVLAGRDLIGIAFTGSGKT 228

  Fly   347 AAFLVPILNQMYELGHVPPPQSTRQYS---RRKQYPLGLVLAPTRELATQIFEEAKKFAYR---- 404
            ..|::|::  |:.|        .::||   .|.:.|.||::.|:||||.|..|..:.::..
  Fly   229 LVFVLPVI--MFAL--------EQEYSLPFERNEGPYGLIICPSRELAKQTHEIIQHYSKHLQAC 283

  Fly   405 --SRMRPAVLYGGNNTSEQMRELDRGCHLIVATPGRLEDMITRGKVGLENIRFLVLDEADRMLDM 467
              ..:|..:..||...||.:..:.||.|::|||||||.||:.:..:.|:..|:|.:||||||:||
  Fly   284 GMPEIRSCLAMGGLPVSEALDVISRGVHIVVATPGRLMDMLDKKILTLDMCRYLCMDEADRMIDM 348

  Fly   468 GFEPQIRRIVEQLNMPPTGQRQTLMFSATFPKQIQELASDFLSNYIFLAVGRVGSTSENITQTIL 532
            |||..:|.|.....    ||||||:||||.||:||..|...|...:.:.|||.|:.|.|:||.:.
  Fly   349 GFEEDVRTIFSFFK----GQRQTLLFSATMPKKIQNFARSALVKPVTINVGRAGAASMNVTQQVE 409

  Fly   533 WVYEPDKRSYLLDLLSSIRDGPEYTKDSLTLIFVETKKGADSLEEFLYQCNHPVTSIHGDRTQKE 597
            :|.:..|..||||.|.  :..|.      .|||.|.|:..|.:.|:|........:|||.:.|:|
  Fly   410 YVKQEAKVVYLLDCLQ--KTAPP------VLIFAEKKQDVDCIHEYLLLKGVEAVAIHGGKDQEE 466

  Fly   598 REEALRCFRSGDCPILVATAVAARGLDIPHVKHVINFDLPSDVEEYVHRIGRTGRMGNLGVATSF 662
            |..|:..:|.|...:||||.||::|||.|:|:||||:|:|.|:|.||||||||||....|:||:.
  Fly   467 RSRAVDAYRVGKKDVLVATDVASKGLDFPNVQHVINYDMPDDIENYVHRIGRTGRSNTKGLATTL 531

  Fly   663 FNE-KNRNICSDLLELLIETKQEIPSFMEDMSSDRGHGGAKRAGRGGGGRYGGGFGSR 719
            .|: ..:::..||..||||.|||:|.|:::::.:..|.... .|...|..|.||.|.|
  Fly   532 INKTTEQSVLLDLKHLLIEGKQEVPDFLDELAPETEHQHLD-LGDSHGCTYCGGLGHR 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bel	NP_001262379.1	DEADc	297..516	CDD:238167	86/227 (38%)
		DEXDc	315..529	CDD:214692	88/222 (40%)
		Helicase_C	538..654	CDD:278689	53/115 (46%)
abs	NP_524220.1	DEADc	179..393	CDD:238167	86/227 (38%)
		DEXDc	192..397	CDD:214692	85/218 (39%)
		Helicase_C	414..523	CDD:278689	53/116 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451565
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47958
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940