DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bel and CG5800

DIOPT Version :9

Sequence 1:	NP_001262379.1	Gene:	bel / 45826	FlyBaseID:	FBgn0263231	Length:	801	Species:	Drosophila melanogaster
Sequence 2:	NP_573230.1	Gene:	CG5800 / 32742	FlyBaseID:	FBgn0030855	Length:	826	Species:	Drosophila melanogaster

Alignment Length:	536	Identity:	153/536 - (28%)
Similarity:	242/536 - (45%)	Gaps:	113/536 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 QQQQPRNDRWQEPERPAG--------FDGSEGGQSAGGNRSYNNRGERGGGGYNSRWKEGGGSNV 249
            |:|:|:.     |.:|..        |.|:.||:.:|.|.....|.|                 :
  Fly     2 QRQKPKG-----PGKPGSRFKPGSGTFKGAGGGRKSGDNSQKRPRQE-----------------I 44

  Fly   250 DYTKLGARDERLEVELFGVGNTGINFD---KYEDIPVEATGQNVPPNITSFDDVQLTEIIRNNVA 311
            :.::|.|.:..::             |   ||.:|...|        |..|....|::..:..:|
  Fly    45 NKSRLAATEAEIQ-------------DLKTKYAEIDATA--------IKKFAQFPLSKKTQKALA 88

  Fly   312 LARYDKPTPVQKHAIPIIINGRDLMACAQTGSGKTAAFLVPILNQMYELGHVPPPQSTRQYSRRK 376
            .:::..||.||:.:|...:.|:|::..|.||||||.|||:|:|..::          ..::||..
  Fly    89 ESKFVHPTQVQRDSIGPALQGKDVLGAAITGSGKTLAFLIPVLEHLF----------MNKWSRTD 143

  Fly   377 QYPLGLVLAPTRELATQIFEEAKKFAYRSRMRPAVLYGGNNTSEQMRELDRGCHLIVATPGR-LE 440
            ... .::::||||||.||||..||..........::.||.|...:...:|: |::::.|||| |:
  Fly   144 GVG-AIIISPTRELAYQIFETLKKVGKHHDFSAGLIIGGKNLKFERTRMDQ-CNILICTPGRLLQ 206

  Fly   441 DMITRGKVGLENIRFLVLDEADRMLDMGFEPQIRRIVEQLNMPPTGQRQTLMFSATFPKQIQELA 505
            .|..........:..||||||||.|||||:..:..|:|  |.||.  ||||:||||....:|:||
  Fly   207 HMDENPLFNTSTMEMLVLDEADRCLDMGFQKTLNSIIE--NFPPV--RQTLLFSATQTNTVQDLA 267

  Fly   506 SDFLSNYIFLAVGRV-------GSTSENITQTILWVYEPDKRSY-LLDLLSSIRDGPEYTKDSL- 561
            ...|.:.:::..|..       .||.:.....:|.|.|..::|| :|:|...|.....:.|:.|
  Fly   268 RLNLKDPVYVGYGGATPREEPSASTKKTPNTAVLAVPELLQQSYVVLNLEDKITMLWSFIKNHLK 332

  Fly   562 --TLIFVETKKGADSLEEFLYQ--C----NHPVTSIHGDRTQKEREEALRCFRSGDCPILVATAV 618
              .::||.:.|.|    ::||:  |    ..|:.:::|...|..|......|......::.:|.|
  Fly   333 QKIIVFVASCKQA----KYLYEIFCKLRPGSPLLALYGTLHQDRRIAIYEDFLRKSHVVMFSTDV 393

  Fly   619 AARGLDIPHVKHVINFDLPSDVEEYVHRIGRTGRMGNLGVATSFFNEKNRNICSDLLELLIETKQ 683
            |:||||.|.|..|:..|.|.||.:|:||.||:.|            .|.|..|     ||:.|..
  Fly   394 ASRGLDFPAVNWVVQLDCPEDVSQYIHRAGRSAR------------NKTRGEC-----LLVLTPS 441

  Fly   684 E----IPSFMEDMSSD 695
            |    |.:..|.::.|
  Fly   442 EEEYMISALKEQLNID 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bel	NP_001262379.1	DEADc	297..516	CDD:238167	77/219 (35%)
		DEXDc	315..529	CDD:214692	77/221 (35%)
		Helicase_C	538..654	CDD:278689	39/125 (31%)
CG5800	NP_573230.1	PRK01297	2..471	CDD:234938	153/536 (29%)
		DEADc	74..277	CDD:238167	77/218 (35%)
		HELICc	311..437	CDD:238034	42/146 (29%)
		DUF4217	474..530	CDD:290667
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451430
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840