DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bel and CG6227

DIOPT Version :9

Sequence 1:	NP_001262379.1	Gene:	bel / 45826	FlyBaseID:	FBgn0263231	Length:	801	Species:	Drosophila melanogaster
Sequence 2:	NP_573020.2	Gene:	CG6227 / 32464	FlyBaseID:	FBgn0030631	Length:	1224	Species:	Drosophila melanogaster

Alignment Length:	614	Identity:	180/614 - (29%)
Similarity:	296/614 - (48%)	Gaps:	99/614 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 LNEQTAEDGQ--AQQQQQPRNDRWQEPE-----RPAGFDGSEGGQSAGGNRSYNNRGERGGGGYN 238
            :.|.|...|:  .::.:||......|||     :|......|........:..||...|.....|
  Fly   331 VEEPTVAAGEKTKKEPEQPHVGAKSEPEVEDKPQPEAEPEDEIDPLDAYMQEVNNEMRRVNNFVN 395

  Fly   239 SRWKEGG---------------------GSNVDYTKLGARDERLEV-------------ELFGVG 269
            ...|..|                     ..|:|..:..:.||..::             ||..:.
  Fly   396 PPAKSQGVVILTGVAKKKTTTLKKGEVIEQNMDSLEYSSEDELEDIRDTAVNLAMKHRKELAKID 460

  Fly   270 NTGINF-----DKYEDIP-------------------VEATGQNVPPNITSFDDVQLT----EII 306
            ::.:.:     :.|.::|                   ::..|:..|..|.::....::    |::
  Fly   461 HSSVTYAPFRKNFYVEVPELTRMTAADVEKYRSDLEGIQVKGKGCPKPIKTWAQCGVSKKEMEVL 525

  Fly   307 RNNVALARYDKPTPVQKHAIPIIINGRDLMACAQTGSGKTAAFLVPILNQMYELGHVPPPQSTRQ 371
            |.    ..::||||:|..|||.|::||||:..|:||||||.||::|:...:.:...:......
  Fly   526 RR----LGFEKPTPIQCQAIPAIMSGRDLIGIAKTGSGKTLAFILPMFRHILDQPSMEDGDGA-- 584

  Fly   372 YSRRKQYPLGLVLAPTRELATQIFEEAKKFAYRSRMRPAVLYGGNNTSEQMRELDRGCHLIVATP 436
                    :.:::||||||..||.::.:||:....:||..:|||...|||:.||.||..:||.||
  Fly   585 --------IAIIMAPTRELCMQIGKDIRKFSKSLGLRPVCVYGGTGISEQIAELKRGAEIIVCTP 641

  Fly   437 GRLEDMI--TRGKV-GLENIRFLVLDEADRMLDMGFEPQIRRIVEQLNMPPTGQRQTLMFSATFP 498
            ||:.||:  ..|:| .|..:.::||||||||.|||||||:.||::  |:.|  .|||:|||||||
  Fly   642 GRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIID--NVRP--DRQTVMFSATFP 702

  Fly   499 KQIQELASDFLSNYIFLAVGRVGSTSENITQTILWVYEPDKRSYLLDLLSSIRDGPEYTKDSLTL 563
            :|::.||...|...|.:.||......:.:.|.::.:.:..|...||:||..      |.:....:
  Fly   703 RQMEALARRILKKPIEVIVGGRSVVCKEVEQHVVILNDDAKFFKLLELLGI------YQEAGSII 761

  Fly   564 IFVETKKGADSLEEFLYQCNHPVTSIHGDRTQKEREEALRCFRSGDCPILVATAVAARGLDIPHV 628
            :||:.::.||.|...|.:.::|..|:||...|.:|:..:..|:||...:|:||:|||||||:..:
  Fly   762 VFVDKQENADILLRDLMKASYPCMSLHGGIDQFDRDSTIIDFKSGKVRLLIATSVAARGLDVKDL 826

  Fly   629 KHVINFDLPSDVEEYVHRIGRTGRMGNLGVATSFFNEKNRNICSDLLELLIETKQEIPSFMEDMS 693
            ..|:|:|:|:..|:||||.|||||.|..|.|.:|...:......|::..:..:...||:.::.:.
  Fly   827 ILVVNYDVPNHYEDYVHRCGRTGRAGKKGSAYTFITPEQSRYAGDIIRAMDLSGTLIPAELQALW 891

  Fly   694 SDRGHGGAKRAGRGGGGRYGGGFGSRDYR 722
            ::.   .|.:...|.....||||..:.::
  Fly   892 TEY---KALQEAEGKTVHTGGGFSGKGFK 917

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bel	NP_001262379.1	DEADc	297..516	CDD:238167	92/225 (41%)
		DEXDc	315..529	CDD:214692	92/216 (43%)
		Helicase_C	538..654	CDD:278689	45/115 (39%)
CG6227	NP_573020.2	SrmB	482..967	CDD:223587	156/463 (34%)
		DEADc	516..719	CDD:238167	92/220 (42%)
		HELICc	733..860	CDD:238034	49/132 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451456
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840