Protein Alignment bel and ddx46

DIOPT Version :10

• Sequence 1: NP_001262379.1
• Gene: bel / 45826
• FlyBaseID: FBgn0263231
• Length: 801
• Species: Drosophila melanogaster
• Sequence 2: NP_001019988.2
• Gene: ddx46 / 321948
• ZFINID: ZDB-GENE-030131-667
• Length: 1035
• Species: Danio rerio
• Alignment Length: 712
• Identity: 202/712 - (28%)
• Similarity: 319/712 - (44%)
• Gaps: 156/712 - (21%)

  Fly   176 GSGSNLNEQTAEDGQAQQQQQPRNDRWQEPERPAGFDGSEG------GQSAGGNRSYNNRGERGG 234
            |...:|.:...:|.:|....:|..|..:|.::.|..:.||.      |:......:|....:...
Zfish   163 GKKWSLEDDDDDDEEAPAPVEPDGDDEEEQDKAAEAEESERMEEEEVGEEVDPLDAYMEEVKEEV 227

  Fly   235 GGYNSRWKEG-----GGSNV---------------------------DYTKLGARDERLEVE--- 264
            ..:|....:|     ||.:|                           |..:..:.:|.::::
Zfish   228 KKFNMGTMKGANDKKGGMSVTKVVTVVKTKKMPHATKKKGELMENDQDAMEYSSEEEEVDLQTAL 292

  Fly   265 ----------LFGVGNTGINFDK-----YEDIP-------------------VEATGQNVPPNIT 295
                      |..|.:..|.::.     |.::|                   :...|:..|..|.
Zfish   293 TGFQTKQRKVLEPVDHQKIQYEPFRKNFYVEVPELARMSPEEVSEYRLELEGISVKGKGCPKPIK 357

  Fly   296 SFDDVQLTEIIRNNVALARYDKPTPVQKHAIPIIINGRDLMACAQTGSGKTAAFLVPILNQMYEL 360
            ::....::..:.|.:....|:||||:|..|||.|::||||:..|:||||||.|||:|:...:.:.
Zfish   358 TWVQCGISMKVLNALKKHNYEKPTPIQAQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHILDQ 422

  Fly   361 GHVPPPQSTRQYSRRKQYPLGLVLAPTRELATQIFEEAKKFAYRSRMRPAVLYGGNNTSEQMREL 425
            ..|...:.          ||.:::.||||||.||.:|.|||:....:|...:|||...|||:.||
Zfish   423 RPVGEAEG----------PLAVIMTPTRELALQITKECKKFSKSLALRVVCVYGGTGISEQIAEL 477

  Fly   426 DRGCHLIVATPGRLEDMI--TRGKV-GLENIRFLVLDEADRMLDMGFEPQIRRIVEQLNMPPTGQ 487
            .||..:||.||||:.||:  ..|:| .|..:.::|:||||||.|||||||:.|||:  |:.|  .
Zfish   478 KRGAEIIVCTPGRMIDMLGANNGRVTNLRRVTYVVIDEADRMFDMGFEPQVMRIVD--NVRP--D 538

  Fly   488 RQTLMFSATFPKQIQELASDFLSNYIFLAVGRVGSTSENITQTILWVYEPDKRSYLLDLLSSIRD 552
            |||:|||||||:.::.||...||..:.:.||.......::.|.::.:.|..|...||::|.
Zfish   539 RQTVMFSATFPRTMEALARRILSKPVEVQVGGRSVVCSDVEQHVIVIEEEKKFLKLLEILG---- 599

  Fly   553 GPEYTKDSLTLIFVETKKGADSLEEFLYQCNHPVTSIHGDRTQKEREEALRCFRSGDCPILVATA 617
              .|.:....:|||:.::.||.|.:.|.:.::|..|:||...|.:|:..:..|::|.|.:||||:
Zfish   600 --HYQEKGSVIIFVDKQEHADGLLKDLMKASYPCMSLHGGIDQYDRDSIINDFKNGACRLLVATS 662

  Fly   618 VAARGLDIPHVKHVINFDLPSDVEEYVHRIGRTGRMGNLGVATSFFNEKNRNICSDLLELLIETK 682
            |||||||:..:..|:|:..|:..|:||||.|||||.||.|.|.:|..|.......|:|:.|..:.
Zfish   663 VAARGLDVKQLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEGQARYSGDILKALELSG 727

  Fly   683 QEIPSFMEDM-----SSDRGHGGAKRAGRGGGGRYGGGFGSRDYRQS------------------ 724
            ..:|:.:|.:     ...:..|...::..|..|: |..|...::..:
Zfish   728 SSVPAELEQLWTNFKEQQKAEGKIIKSSSGFSGK-GFKFDETEHALANERKKLQKAALGLHDSDD 791

  Fly   725 ------------------------------SGGGGGGRSGPPPRSGGSGSGGGGGSYRSNGN 756
                                          |.|..||.||    |..:.||.|..|..|.||
Zfish   792 EDTALDIDEQIESMFNSKKRVKDFSAPGSVSAGSAGGVSG----SVSAVSGLGSLSTPSAGN 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bel	NP_001262379.1	DEADc_DDX3	275..522	CDD:350809	103/273 (38%)
		SF2_C_DEAD	527..663	CDD:350174	51/135 (38%)
ddx46	NP_001019988.2	Q motif	357..385		6/27 (22%)
		DEAD box	514..517		2/2 (100%)