Protein Alignment bel and glh-2

DIOPT Version :10

• Sequence 1: NP_001262379.1
• Gene: bel / 45826
• FlyBaseID: FBgn0263231
• Length: 801
• Species: Drosophila melanogaster
• Sequence 2: NP_491876.1
• Gene: glh-2 / 172361
• WormBaseID: WBGene00001599
• Length: 974
• Species: Caenorhabditis elegans
• Alignment Length: 861
• Identity: 279/861 - (32%)
• Similarity: 394/861 - (45%)
• Gaps: 202/861 - (23%)

  Fly     6 NQNGTGLEQQVAGLDLNGGSADYSGPITSKTSTNSVTGGVYVPPHLRGGGGNNNAADAESQGQGQ 70
            |..|||.     |....||:...||........:...||.       |.|||:|:    ..|.|.
 Worm   152 NAGGTGF-----GSGNAGGTGFGSGKAGGTGFGSGKAGGT-------GFGGNSNS----GSGFGS 200

  Fly    71 GQGQGFDSRSGNPRQETRDPQQSRGGGGEYRRGGGG--GGRGFNRQSGDYGYGSGGGGRRGG--- 130
            |...||.  |||       ..:|..|||:....|||  ||.||.......|:||||||:..|
 Worm   201 GLTNGFG--SGN-------NHESGFGGGKSGGFGGGNSGGSGFGSGGNSNGFGSGGGGQDRGERN 256

  Fly   131 ---------GGRFED-------------------NYNGGEF-------DSRRG--GDWNRSGGGG 158
                     |.|..|                   .:|..:.       :.|.|  |..:..|||.
 Worm   257 NNCFNCQQPGHRSNDCPEPKKEREPRVCYNCQQPGHNSRDCPEERKPREGRNGFTGGSSGFGGGN 321

  Fly   159 GGGRGF------GRGPSYRG----GGGGSGSNLN-------------------------EQTAED 188
            |||.||      |.|....|    |.||.|.|.|                         .::.:.
 Worm   322 GGGTGFDSGLTNGFGSGNNGESGFGSGGFGGNSNGFGSGGGGQDRGERNNNCFNCQQPGHRSNDC 386

  Fly   189 GQAQQQQQPR----------NDR-WQEPERP--------AGFDGSEGGQSAGGN-RSYNNRGERG 233
            .:.:::::||          |.| ..|..:|        :||.|...|...||| ..:.|..|||
 Worm   387 PEPKKEREPRVCYNCQQPGHNSRDCPEERKPREGRNGFTSGFGGGNDGGFGGGNAEGFGNNEERG 451

  Fly   234 --------GGGYNS------------------------------RWKEGGGSNVDYTKLGARDER 260
                    |.|:.|                              ...||.|....|..:   ::.
 Worm   452 PMKCFNCKGEGHRSAECPEPPRGCFNCGEQGHRSNECPNPAKPREGAEGEGPKATYVPV---EDN 513

  Fly   261 LEVELFGVG--NTGINFDKYEDIPVEATGQNVPPNI---TSFDDVQLTEIIRNNVALARYDKPTP 320
            :| |:|.:.  :.|:.|:|:.|..|:.|....|..:   .:|.:..|.|.::.|||.|.|.|.||
 Worm   514 ME-EVFNMQKISEGLMFNKFFDAEVKITSDKKPVGVKTCKTFSEANLGETMKKNVAHAGYTKTTP 577

  Fly   321 VQKHAIPIIINGRDLMACAQTGSGKTAAFLVPILNQMYELGHVPPPQSTRQYSRRKQYPLGLVLA 385
            :|::.:|:|..|.|:|||||||||||||||:||:.::.:      ............||..::|.
 Worm   578 IQQYTLPLIHQGHDIMACAQTGSGKTAAFLLPIMARLID------ENDLNTAGEGGCYPRCIILT 636

  Fly   386 PTRELATQIFEEAKKFAYRSRMRPAVLYGGNNTSEQMRELDRGCHLIVATPGRLEDMITRGKVGL 450
            |||||..||:.|.:||||::.|....:|||........::::|..:||.|.||::.....|.:.|
 Worm   637 PTRELTDQIYNEGRKFAYQTMMEIRPVYGGLAVGYNKGQIEKGATIIVGTVGRIKHFCEEGTIKL 701

  Fly   451 ENIRFLVLDEADRMLD-MGFEPQIRRIVEQLNMPPTGQRQTLMFSATFPKQIQELASDFL-SNYI 513
            :..||.||||||||:| |||...|..||...:||....|||||||||||..:||.|.:.| ..||
 Worm   702 DKCRFFVLDEADRMIDAMGFGTDIDTIVNYESMPKKENRQTLMFSATFPDSVQEAARNHLKEGYI 766

  Fly   514 FLAVGRVGSTSENITQTILWVYEPDKRSYLLDLL-------SSIRDGPEYTKDSLTLIFVETKKG 571
            .||:.::|:.::.:.|........:|:..||::|       ::.::...|||.  |::||..:..
 Worm   767 MLAIDKIGAANKCVLQEFEKCDRSEKKDKLLEILGIDIDSYTTEKNSEVYTKK--TIVFVSQRAM 829

  Fly   572 ADSLEEFLYQCNHPVTSIHGDRTQKEREEALRCFRSGDCPILVATAVAARGLDIPHVKHVINFDL 636
            ||:|...|.....|..:|||.|.|:||.||||.||:|..|:|:|||||.|||||..|.||||:|:
 Worm   830 ADTLASILSSAQVPAITIHGAREQRERSEALRQFRNGSKPVLIATAVAERGLDIKGVDHVINYDM 894

  Fly   637 PSDVEEYVHRIGRTGRMGNLGVATSFFNEKNRNICSDLLELLIETKQEIPSFMEDMSSDRGHGGA 701
            |.::::|:||||||||:||.|.||||.:| :.|:.|:|:.:|.:..|.:|.:|:..|
 Worm   895 PDNIDDYIHRIGRTGRVGNAGRATSFISE-DCNLLSELVRVLSDADQLVPEWMQGAS-------- 950

  Fly   702 KRAGRGGGGRYGGGFG 717
                   ||.:|..||
 Worm   951 -------GGNFGASFG 959

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bel	NP_001262379.1	DEADc_DDX3	275..522	CDD:350809	104/251 (41%)
		SF2_C_DEAD	527..663	CDD:350174	64/142 (45%)
glh-2	NP_491876.1	Keratin_2_head	73..>177	CDD:465068	9/29 (31%)
		PTZ00368	<250..300	CDD:173561	5/49 (10%)
		PTZ00368	373..508	CDD:173561	23/134 (17%)
		SrmB	553..924	CDD:440279	165/379 (44%)