Protein Alignment bel and Ddx4

DIOPT Version :10

• Sequence 1: NP_001262379.1
• Gene: bel / 45826
• FlyBaseID: FBgn0263231
• Length: 801
• Species: Drosophila melanogaster
• Sequence 2: XP_011242920.1
• Gene: Ddx4 / 13206
• MGIID: 102670
• Length: 738
• Species: Mus musculus
• Alignment Length: 762
• Identity: 310/762 - (40%)
• Similarity: 422/762 - (55%)
• Gaps: 107/762 - (14%)

  Fly    24 GSADYSGPITSKTSTNSVTGGVYVP-----PHLRGGGGNN-NAADAES-----------QGQGQG 71
            |..|:...|. |...:|     |||     .:..|..|:. |...|.|           .|:...
Mouse     2 GDEDWEAEIL-KPHVSS-----YVPVFEKDKYSSGANGDTFNRTSASSVLFALEMEDGPSGRDDF 60

  Fly    72 QGQGFDS-RSGNPR---QETRDPQQSRGGGGEYRRGGGGGGRGFNRQSGDYGYGSGGGGRRGGGG 132
            ...||.| ||...|   :.::....|..||  :.||.|.|.|||  .:..:..|...|..:....
Mouse    61 MRSGFPSGRSLGSRDIGESSKKENTSTTGG--FGRGKGFGNRGF--LNNKFEEGDSSGFWKESNN 121

  Fly   133 RFEDNYNGGEFDSRRGG--DWNRSGGGGGGGRGFGRGPSYRGGGGGSGSNLNEQTAEDGQAQQQQ 195
            ..|||.......|:|||  |.|.|...|...|| ||| |:||..||.|  |....:|..|.|..|
Mouse   122 DCEDNQTRSRGFSKRGGCQDGNDSEASGPFRRG-GRG-SFRGCRGGFG--LGRPNSESDQDQGTQ 182

  Fly   196 QPRNDRWQEPERPAGFDGSEGGQSAGGN-RSYNNRGERGGGGY------------NSRWK---EG 244
              |........:||   .|:..|...|| .:|.:|...|.|||            .:.||   ||
Mouse   183 --RGGGLFGSRKPA---ASDSVQCLTGNGDTYQSRSGSGRGGYKGLNEEVVTGSGKNSWKSETEG 242

  Fly   245 G------GSNVDYTKLGARDERLEVELFGVGNTGINFDKYEDIPVEATGQNVPPNITSFDDVQLT 303
            |      |..|.|......::  |..:|....||||||||:.|.||.:|.:.||.|.:|::..|.
Mouse   243 GESSDSQGPKVTYIPPPPPED--EDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLC 305

  Fly   304 EIIRNNVALARYDKPTPVQKHAIPIIINGRDLMACAQTGSGKTAAFLVPILNQMYELGHVPPPQS 368
            :.:.||:|.|.|.|.|||||::|||::.|||||||||||||||||||:|||..|...|      .
Mouse   306 QTLNNNIAKAGYTKLTPVQKYSIPIVLAGRDLMACAQTGSGKTAAFLLPILAHMMRDG------I 364

  Fly   369 TRQYSRRKQYPLGLVLAPTRELATQIFEEAKKFAYRSRMRPAVLYGGNNTSEQMRELDRGCHLIV 433
            |....:..|.|..:::||||||..||:.||:||::.:.:|..|:|||......:|::.:||:::.
Mouse   365 TASRFKELQEPECIIVAPTRELINQIYLEARKFSFGTCVRAVVIYGGTQFGHSVRQIVQGCNILC 429

  Fly   434 ATPGRLEDMITRGKVGLENIRFLVLDEADRMLDMGFEPQIRRIVEQLNMPPTGQRQTLMFSATFP 498
            ||||||.|:|.:.|:||:.:::||||||||||||||.|::::::....||...|||||:||||||
Mouse   430 ATPGRLMDIIGKEKIGLKQVKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLLFSATFP 494

  Fly   499 KQIQELASDFL-SNYIFLAVGRVGSTSENITQTILWVYEPDKRSYLLDLLSSIRDGPEYTKDSLT 562
            ::||.||.||| |:|:|:|||:||....::.||||.|.:..||..|:::|.:|       .|..|
Mouse   495 EEIQRLAGDFLKSSYLFVAVGQVGGACRDVQQTILQVGQYSKREKLVEILRNI-------GDERT 552

  Fly   563 LIFVETKKGADSLEEFLYQCNHPVTSIHGDRTQKEREEALRCFRSGDCPILVATAVAARGLDIPH 627
            ::||||||.||.:..||.|.....|||||||.|:|||:||..||.|.||:||||:||||||||.:
Mouse   553 MVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRCGKCPVLVATSVAARGLDIEN 617

  Fly   628 VKHVINFDLPSDVEEYVHRIGRTGRMGNLGVATSFFN-EKNRNICSDLLELLIETKQEIPSFMED 691
            |:|||||||||.::|||||||||||.||.|.|.|||: :.:.::...|:::|.:.:|::|:::|:
Mouse   618 VQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDTDSDNHLAQPLVKVLSDAQQDVPAWLEE 682

  Fly   692 M-----------SSDRGHGGAKRAGRGGGGRYGGGFGSRDYRQSSGG 727
            :           ||.||               |..|.|.|.|::..|
Mouse   683 IAFSTYVPPSFSSSTRG---------------GAVFASVDTRKNYQG 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bel	NP_001262379.1	DEADc_DDX3	275..522	CDD:350809	127/247 (51%)
		SF2_C_DEAD	527..663	CDD:350174	79/135 (59%)
Ddx4	XP_011242920.1	DEADc_DDX4	266..518	CDD:350810	131/257 (51%)
		SF2_C_DEAD	524..653	CDD:350174	79/135 (59%)