DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Abl and RKF1

DIOPT Version :9

Sequence 1:	NP_001261962.1	Gene:	Abl / 45821	FlyBaseID:	FBgn0000017	Length:	1723	Species:	Drosophila melanogaster
Sequence 2:	NP_174268.7	Gene:	RKF1 / 839853	AraportID:	AT1G29750	Length:	1021	Species:	Arabidopsis thaliana

Alignment Length:	332	Identity:	88/332 - (26%)
Similarity:	147/332 - (44%)	Gaps:	43/332 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   388 DIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTL-KEDTMALKDFLEEAAIMKEMKHPNLVQLIGV 451
            |....:|:|.|.:|.|::.|... |..||||.| .:.....::||.|...:..::|||||:|.|.
plant   680 DFNPTNKIGEGGFGAVFKGVLAD-GRVVAVKQLSSKSRQGNREFLNEIGAISCLQHPNLVKLHGF 743

  Fly   452 CTREPPFYIITEFMSHGNLLDFLRSAGRE--TLDAVALLYMATQIASGMSYLESRN---YIHRDL 511
            |.......:..|:|.:.:|...|.|...:  .:|......:...||.|:::|...:   ::|||:
plant   744 CVERAQLLLAYEYMENNSLSSALFSPKHKQIPMDWPTRFKICCGIAKGLAFLHEESPLKFVHRDI 808

  Fly   512 AARNCLVGDNKLVKVADFGLARLMRDDTYTAHAGAKF--PIKWTAPEGLAYNKFSTKSDVWAFGV 574
            .|.|.|:..:...|::|||||||  |:....|...|.  .|.:.|||...:...:.|:||::|||
plant   809 KATNILLDKDLTPKISDFGLARL--DEEEKTHISTKVAGTIGYMAPEYALWGYLTFKADVYSFGV 871

  Fly   575 LLWEIA-----TYGMSPYPAIDLTDVYHK-LDKGYRME------RPPGCPPE---VYDLMRQCWQ 624
            |:.||.     :..|....::.|.:..:: ::.|:.|:      ||.....|   |..:...|..
plant   872 LVLEIVAGITNSNFMGAGDSVCLLEFANECVESGHLMQVVDERLRPEVDRKEAEAVIKVALVCSS 936

  Fly   625 WDATDRPTFKSIHHALEHMFQESSITEAVEK-----------------QLNANATSASSSAPSTS 672
            ...||||....:...||.::.....|..|.:                 :.|:....:..|.||:|
plant   937 ASPTDRPLMSEVVAMLEGLYPVPESTPGVSRNAGDIRFKAFKDLRRGMENNSKTQCSVKSYPSSS 1001

  Fly   673 GVATGGG 679
            ..::|.|
plant  1002 STSSGAG 1008

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Abl	NP_001261962.1	SH3_Abl	209..263	CDD:212784
		SH2_ABL	268..363	CDD:198189
		PTKc_Abl	382..644	CDD:270645	79/278 (28%)
		Pkinase_Tyr	389..640	CDD:285015	76/273 (28%)
		FABD	1584..1723	CDD:197885
RKF1	NP_174268.7	LRR	112..395	CDD:227223
		leucine-rich repeat	125..147	CDD:275380
		leucine-rich repeat	148..170	CDD:275380
		leucine-rich repeat	171..194	CDD:275380
		leucine-rich repeat	195..218	CDD:275380
		leucine-rich repeat	219..242	CDD:275380
		leucine-rich repeat	243..266	CDD:275380
		leucine-rich repeat	267..287	CDD:275380
		leucine-rich repeat	291..314	CDD:275380
		leucine-rich repeat	315..337	CDD:275380
		leucine-rich repeat	338..356	CDD:275380
		Malectin	417..604	CDD:288557
		STYKc	686..952	CDD:214568	76/268 (28%)
		STKc_IRAK	687..955	CDD:270968	77/270 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000