Protein Alignment Abl and CTR1

DIOPT Version :10

• Sequence 1: NP_001261962.1
• Gene: Abl / 45821
• FlyBaseID: FBgn0000017
• Length: 1723
• Species: Drosophila melanogaster
• Sequence 2: NP_195993.1
• Gene: CTR1 / 831748
• AraportID: AT5G03730
• Length: 821
• Species: Arabidopsis thaliana
• Alignment Length: 843
• Identity: 204/843 - (24%)
• Similarity: 299/843 - (35%)
• Gaps: 273/843 - (32%)

  Fly    27 LSSSPVASVSPHCISSSSGVSSAPLGGGSTLRGSRIKSSSSGVASGSGSG------GGGGGSGSG 85
            :|.|...:..||..|.||.            ..|...|.::|.|.....|      |||||
plant    21 VSVSVTGAPPPHYDSLSSE------------NRSNHNSGNTGKAKAERGGFDWDPSGGGGG---- 69

  Fly    86 LSQRSGGHKDARCN--PT-VGLNIFTEHNGTKH----SSF--RGHPGKYHMNLEALLQSRPLPHI 141
                     |.|.|  |. ||.|::....|.:.    |||  ....|.|:|
plant    70 ---------DHRLNNQPNRVGNNMYASSLGLQRQSSGSSFGESSLSGDYYM-------------- 111

  Fly   142 PAGSTAASLLADAAELQQHQQDSG---GLGLQGSSL--------GGGHSSTTSVFES-------- 187
            |..|.||:.:    |.....||.|   |.|..|..|        .||.||..|..:.
plant   112 PTLSAAANEI----ESVGFPQDDGFRLGFGGGGGDLRIQMAADSAGGSSSGKSWAQQTEESYQLQ 172

  Fly   188 ---AHRWTSK------ENLLAPGPEED-------------------------------------- 205
               |.|.:|:      .|.|.|.|:|.
plant   173 LALALRLSSEATCADDPNFLDPVPDESALRTSPSSAETVSHRFWVNGCLSYYDKVPDGFYMMNGL 237

  Fly   206 DPQLFVALYDFQAGG-----ENQLSLKKG------------------------------------ 229
            ||.::....|....|     |:..::..|
plant   238 DPYIWTLCIDLHESGRIPSIESLRAVDSGVDSSLEAIIVDRRSDPAFKELHNRVHDISCSCITTK 302

  Fly   230 ---EQVRILSYNKSG------------EWCEAHSDSGNVGWVPSNYVTPLNSLEKHSWYHGPI-- 277
               :|:..|..|:.|            .|.|.......:..|    |.|:.||......|..:
plant   303 EVVDQLAKLICNRMGGPVIMGEDELVPMWKECIDGLKEIFKV----VVPIGSLSVGLCRHRALLF 363

  Fly   278 ---------------------SRNAAEYLLSSGINGSFLVR---------ESES---SPGQRSIS 309
                                 ..:||..|:..|::..:||.         |.:|   .|...|||
plant   364 KVLADIIDLPCRIAKGCKYCNRDDAASCLVRFGLDREYLVDLVGKPGHLWEPDSLLNGPSSISIS 428

  Fly   310 --LRY----------EGRVYHYRISEDPDGKVFVTQEAKFNTLAELVH---------HHSVPHEG 353
              ||:          :.|:...:...|......|...|..:....:.|         :.::...|
plant   429 SPLRFPRPKPVEPAVDFRLLAKQYFSDSQSLNLVFDPASDDMGFSMFHRQYDNPGGENDALAENG 493

  Fly   354 HGLITPLLYPAPK-----QNKPTVFPLSPEP-----------------DEWEICRTDIMMKHKLG 396
            .|.:.|.....|:     .|:....|::..|                 |:.:|...|:.:|.|:|
plant   494 GGSLPPSANMPPQNMMRASNQIEAAPMNAPPISQPVPNRANRELGLDGDDMDIPWCDLNIKEKIG 558

  Fly   397 GGQYGEVYEAVWKRYGNTVAVKTLKEDTM---ALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPF 458
            .|.:|.|:.|.|  :|:.||||.|.|...   .:.:||.|.||||.::|||:|..:|..|:.|..
plant   559 AGSFGTVHRAEW--HGSDVAVKILMEQDFHAERVNEFLREVAIMKRLRHPNIVLFMGAVTQPPNL 621

  Fly   459 YIITEFMSHGNLLDFLRSAG-RETLDAVALLYMATQIASGMSYLESRN--YIHRDLAARNCLVGD 520
            .|:||::|.|:|...|..:| ||.||....|.||..:|.||:||.:||  .:||||.:.|.||..
plant   622 SIVTEYLSRGSLYRLLHKSGAREQLDERRRLSMAYDVAKGMNYLHNRNPPIVHRDLKSPNLLVDK 686

  Fly   521 NKLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMS 585
            ...|||.||||:||......::.:.|..| :|.|||.|.....:.||||::|||:|||:||. ..
plant   687 KYTVKVCDFGLSRLKASTFLSSKSAAGTP-EWMAPEVLRDEPSNEKSDVYSFGVILWELATL-QQ 749

  Fly   586 PYPAIDLTDVYHKLD-KGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHMFQES 647
            |:..::...|...:. |..|:|.|....|:|..::..||..:...||:|.:|...|..:.:.:
plant   750 PWGNLNPAQVVAAVGFKCKRLEIPRNLNPQVAAIIEGCWTNEPWKRPSFATIMDLLRPLIKSA 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abl	NP_001261962.1	SH3_Abl	209..263	CDD:212784	12/109 (11%)
		SH2_ABL	268..363	CDD:198189	23/150 (15%)
		PTKc_Abl	382..644	CDD:270645	103/268 (38%)
		FABD	1584..1723	CDD:197885
CTR1	NP_195993.1	EDR1	207..412	CDD:433922	24/208 (12%)
		STKc_MAP3K-like	557..805	CDD:270901	98/251 (39%)