DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Abl and STY17

DIOPT Version :9

Sequence 1:	NP_001261962.1	Gene:	Abl / 45821	FlyBaseID:	FBgn0000017	Length:	1723	Species:	Drosophila melanogaster
Sequence 2:	NP_195303.2	Gene:	STY17 / 829731	AraportID:	AT4G35780	Length:	570	Species:	Arabidopsis thaliana

Alignment Length:	304	Identity:	103/304 - (33%)
Similarity:	161/304 - (52%)	Gaps:	27/304 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   363 PAPKQNKPTVF----------PLSPE-----PDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYG 412
            |..||...|.|          |...|     .|||||....:.::.|:..|.|||::...:  ..
plant   251 PCSKQKSITFFEHDKSTNELLPACVEIPTDGTDEWEIDMKQLKIEKKVACGSYGELFRGTY--CS 313

  Fly   413 NTVAVKTLKEDTM---ALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFL 474
            ..||:|.||.:.:   .|::|.:|..||::::|.|:||.||.|||.|...|:||||:.|::.|||
plant   314 QEVAIKILKPERVNAEMLREFSQEVYIMRKVRHKNVVQFIGACTRSPNLCIVTEFMTRGSIYDFL 378

  Fly   475 RSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMRDD- 538
            .. .:......:||.:|..::.||:||...|.|||||...|.|:.::::|||||||:||:..:.
plant   379 HK-HKGVFKIQSLLKVALDVSKGMNYLHQNNIIHRDLKTANLLMDEHEVVKVADFGVARVQTESG 442

  Fly   539 TYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAI-DLTDVYHKLDKG 602
            ..||..|.   .:|.|||.:.:..:..::||:::.::|||:.| |..||..: .|......:.||
plant   443 VMTAETGT---YRWMAPEVIEHKPYDHRADVFSYAIVLWELLT-GELPYSYLTPLQAAVGVVQKG 503

  Fly   603 YRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHMFQE 646
            .|.:.|....|::.:|:.:|||.|...||.|..|...|..:.:|
plant   504 LRPKIPKETHPKLTELLEKCWQQDPALRPNFAEIIEMLNQLIRE 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Abl	NP_001261962.1	SH3_Abl	209..263	CDD:212784
		SH2_ABL	268..363	CDD:198189	103/304 (34%)
		PTKc_Abl	382..644	CDD:270645	93/266 (35%)
		Pkinase_Tyr	389..640	CDD:285015	89/255 (35%)
		FABD	1584..1723	CDD:197885
STY17	NP_195303.2	ACT_TyrKc	178..244	CDD:153200
STY17	NP_195303.2	STKc_MAP3K-like	301..541	CDD:270901	88/246 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	165	1.000	Domainoid score	I1208
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	1	1.000	-	-		otm2536
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X88
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910