Protein Alignment Abl and ptk6b

DIOPT Version :10

• Sequence 1: NP_001261962.1
• Gene: Abl / 45821
• FlyBaseID: FBgn0000017
• Length: 1723
• Species: Drosophila melanogaster
• Sequence 2: NP_001070140.1
• Gene: ptk6b / 767734
• ZFINID: ZDB-GENE-060929-1150
• Length: 511
• Species: Danio rerio
• Alignment Length: 476
• Identity: 189/476 - (39%)
• Similarity: 289/476 - (60%)
• Gaps: 24/476 - (5%)

  Fly   186 ESAHRWTSKENLLAPGP--EEDDPQLFVALYDFQAGGENQLSLKKGEQVRILSYNKSGEWCEAHS 248
            |:..|: ||..:..|.|  ..::..:::||:||:|..:.:||.|.|::..|.  ::||:|..|:.
Zfish    46 ETERRY-SKPKIKPPLPPSANNNAAIYMALWDFKARNDQELSFKAGDKFEIT--DRSGDWWTANK 107

  Fly   249 DS--GNV--GWVPSNYVTPLNSLEKHSWYHGPISR-NAAEYLLSSGIN-GSFLVRESESSPGQRS 307
            ..  |.|  |:||.||:. .:|:|...|:.|.::| .|..:|:|...| ||||||.|||......
Zfish   108 KDIFGRVTTGFVPYNYLA-RDSVESQPWFFGKMNRVGAVSHLMSDENNYGSFLVRVSESDDMGYV 171

  Fly   308 ISLRYEGRVYHYRISEDPDGKVFVTQEAKFNTLAELVHHHSVPHEGHGL-ITPLLYPAPKQNKPT 371
            :|:|.:....|::|.:..| :.:|....||:::.|::.|    ::.|.| |..||.....:.||.
Zfish   172 LSVRTKENAKHFKIFQTGD-QFYVDALFKFSSIVEVIEH----YQSHPLSIGDLLSEPCIRIKPE 231

  Fly   372 VFPLSPEPDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLK-EDTMALKDFLEEAA 435
            ..| .|..||||:.:.:..::::||.|.:.:||...||.: :.||:|.|| .|.:.|::|..|..
Zfish   232 NVP-PPSTDEWELPKEEFQLENQLGSGHFADVYSGKWKNH-SKVAIKILKNNDALVLREFQLEVQ 294

  Fly   436 IMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSY 500
            |||.::|.:|:.|..|||...|||||||.:..|:||.|||:....:|...:|:.||.|:|.||:|
Zfish   295 IMKRLRHKHLISLFAVCTSSSPFYIITELIEKGDLLHFLRNPEGRSLQMESLIDMAAQVADGMAY 359

  Fly   501 LESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNKFST 565
            ||:.|.|||||||||.||||..:.|:|||||||::::..|.:. ..|.|.||||||.:.:..:|:
Zfish   360 LEANNSIHRDLAARNVLVGDGYVCKIADFGLARIIKEPVYLSD-DKKIPYKWTAPEAIGHGTYSS 423

  Fly   566 KSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDK-GYRMERPPGCPPEVYDLMRQCWQWDATD 629
            |||||:||:||:||.|:|..|||.::..:||..:.| .|||..||.||..:|::||.||:.::.|
Zfish   424 KSDVWSFGILLYEIVTHGGIPYPGVNTGEVYDLITKENYRMPSPPKCPQAIYNIMRACWRIESVD 488

  Fly   630 RPTFKSIHHALE-HMFQESSI 649
            ||.||.:...|: :..|.||:
Zfish   489 RPNFKVLKDELDNYQGQYSSV 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abl	NP_001261962.1	SH3_Abl	209..263	CDD:212784	21/57 (37%)
		SH2_ABL	268..363	CDD:198189	32/97 (33%)
		PTKc_Abl	382..644	CDD:270645	120/264 (45%)
		FABD	1584..1723	CDD:197885
ptk6b	NP_001070140.1	SH3_Brk	70..126	CDD:212781	21/58 (36%)
		SH2	132..216	CDD:214585	27/88 (31%)
		PTKc_Srm_Brk	241..502	CDD:133248	120/262 (46%)