DRSC/TRiP Functional Genomics Resources

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Protein Alignment Abl and nck1

DIOPT Version :10

Sequence 1:NP_001261962.1 Gene:Abl / 45821 FlyBaseID:FBgn0000017 Length:1723 Species:Drosophila melanogaster
Sequence 2:NP_001008101.1 Gene:nck1 / 493463 XenbaseID:XB-GENE-6085807 Length:377 Species:Xenopus tropicalis


Alignment Length:183 Identity:59/183 - (32%)
Similarity:92/183 - (50%) Gaps:37/183 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   212 ALYDFQAGGENQLSLKKGEQVRILSYNKSG-EWCEAHSDSGNVGWVPSNYVT------PLNSLEK 269
            |||.|.:..|.:|:.:|||.:.::...::. ||.:....:|.||.||.||||      |..|.|.
 Frog   197 ALYPFSSSNEEELNFEKGEVMDVIEKPENDPEWWKCRKSNGLVGLVPKNYVTIMQNFQPTPSFEP 261

  Fly   270 ------------------HSWYHGPISRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRYEGR 315
                              :.||:|.::|:.||..|:. |..|.||:|:|||||...|:||:.:|:
 Frog   262 LPPRCDYIGPSASGRFAGNQWYYGKVTRHQAEMALNERGNEGDFLIRDSESSPNDFSVSLKAQGK 326

  Fly   316 VYHYRIS-EDPDGKVFVTQEAKFNTLAELVHHH-------SVPHEGHGLITPL 360
            ..|:::. :|   .::...:.||:|:.|||.|:       |...|...||.||
 Frog   327 NKHFKVQMKD---CMYCIGQRKFSTMEELVEHYKKAPIFTSEQGEKLYLIKPL 376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AblNP_001261962.1 SH3_Abl 209..263 CDD:212784 20/57 (35%)
SH2_ABL 268..363 CDD:198189 37/120 (31%)
PTKc_Abl 382..644 CDD:270645
FABD 1584..1723 CDD:197885
nck1NP_001008101.1 SH3_Nck1_1 4..62 CDD:212833
SH3_Nck1_2 108..162 CDD:212834
SH3_Nck1_3 193..249 CDD:212837 19/51 (37%)
SH2_Nck1 280..376 CDD:198271 34/98 (35%)
Blue background indicates that the domain is not in the aligned region.

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