Protein Alignment Abl and Eph

DIOPT Version :10

• Sequence 1: NP_001261962.1
• Gene: Abl / 45821
• FlyBaseID: FBgn0000017
• Length: 1723
• Species: Drosophila melanogaster
• Sequence 2: NP_524625.3
• Gene: Eph / 43803
• FlyBaseID: FBgn0025936
• Length: 1096
• Species: Drosophila melanogaster
• Alignment Length: 291
• Identity: 128/291 - (43%)
• Similarity: 175/291 - (60%)
• Gaps: 17/291 - (5%)

  Fly   383 EICRTDIMMKHKLGGGQYGEVYEAVWKRYGN-----TVAVKTLK--EDTMALKDFLEEAAIMKEM 440
            ||....|.::..:|||::|:|.....|...|     .||:||||  ....|..|||.||:||.:.
  Fly   735 EIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQF 799

  Fly   441 KHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLR-SAGR-ETLDAVALLYMATQIASGMSYLES 503
            .|||::.|.||.||..|..||||:|.:|:|..||| :.|: :||.   |:.|...||||||||..
  Fly   800 DHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQ---LIVMLRGIASGMSYLSD 861

  Fly   504 RNYIHRDLAARNCLVGDNKLVKVADFGLARLMRD--DTYTAHAGAKFPIKWTAPEGLAYNKFSTK 566
            .||:||||||||.||....:.|:|||||:|.:.:  |.||.. |.|.|::|||||.:|:.||::.
  Fly   862 MNYVHRDLAARNVLVNAQLICKIADFGLSREIENASDAYTTR-GGKIPVRWTAPEAIAFRKFTSA 925

  Fly   567 SDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQCWQWDATDRP 631
            ||||::||:|||:.:||..||......||...::||||:..|..||..:|.||..|||...|.||
  Fly   926 SDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRP 990

  Fly   632 TFKSIHHALEHMFQ--ESSITEAVEKQLNAN 660
            ||.||...|:::.:  :|.:|.....:.:.|
  Fly   991 TFASIVSTLDNLARQPQSLLTTRPSPESDGN 1021

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abl	NP_001261962.1	SH3_Abl	209..263	CDD:212784
		SH2_ABL	268..363	CDD:198189
		PTKc_Abl	382..644	CDD:270645	125/271 (46%)
		FABD	1584..1723	CDD:197885
Eph	NP_524625.3	EphR_LBD	85..260	CDD:198439
		FN3	387..476	CDD:238020
		FN3	536..623	CDD:238020
		EphA2_TM	640..738	CDD:464211	2/2 (100%)
		PTKc_EphR	736..1002	CDD:270629	124/269 (46%)
		SAM_1	1029..1092	CDD:425739