DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Abl and CG10702

DIOPT Version :9

Sequence 1:	NP_001261962.1	Gene:	Abl / 45821	FlyBaseID:	FBgn0000017	Length:	1723	Species:	Drosophila melanogaster
Sequence 2:	NP_001188841.1	Gene:	CG10702 / 35181	FlyBaseID:	FBgn0032752	Length:	946	Species:	Drosophila melanogaster

Alignment Length:	185	Identity:	36/185 - (19%)
Similarity:	61/185 - (32%)	Gaps:	62/185 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   342 ELVHHHSVP----HEGHGLITP----------LLYPAPKQNKPT--VFPLSP-EPDEWEICRTDI 389
            ||:|...:|    ||...|..|          ||:|.......|  :|.|.. :||     ...:
  Fly   489 ELIHRPLLPGKLYHEESELDAPICTRINWKRRLLFPDDLIENGTHYLFDLDDLQPD-----TRYV 548

  Fly   390 MMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKEDTMALKDFLEEAAIMKEMKHPNLVQLIGVCTR 454
            ::....|..:..|.|||                     :..|.......::..|.|::|:    :
  Fly   549 VLLRTFGNDEAHEAYEA---------------------RSELTYVQTELDIPKPPLLELV----K 588

  Fly   455 EPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHR 509
            :....:..:..||               |.|:.|....:::....|:|.|||.|:
  Fly   589 KTDSSLTVQMASH---------------DHVSFLLTVFELSDDQDYIEQRNYCHQ 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Abl	NP_001261962.1	SH3_Abl	209..263	CDD:212784
		SH2_ABL	268..363	CDD:198189	10/34 (29%)
		PTKc_Abl	382..644	CDD:270645	20/128 (16%)
		Pkinase_Tyr	389..640	CDD:285015	20/121 (17%)
		FABD	1584..1723	CDD:197885
CG10702	NP_001188841.1	Recep_L_domain	47..159	CDD:279382
		Furin-like	171..297	CDD:279142
		FU	210..258	CDD:238021
		Recep_L_domain	328..441	CDD:279382
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468390
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930