Protein Alignment Abl and old-1

DIOPT Version :10

• Sequence 1: NP_001261962.1
• Gene: Abl / 45821
• FlyBaseID: FBgn0000017
• Length: 1723
• Species: Drosophila melanogaster
• Sequence 2: NP_496130.2
• Gene: old-1 / 191737
• WormBaseID: WBGene00003862
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 313
• Identity: 103/313 - (32%)
• Similarity: 156/313 - (49%)
• Gaps: 43/313 - (13%)

  Fly   388 DIMMKHKLGGGQYGEVYEAVWKRYGNT----------VAVK-TLKEDTMALKDFL-EEAAIMKEM 440
            ||.....||.|::|.:.:. :.|..|:          |||| .|.|.....::.: :|..:|..:
 Worm   174 DISKGRPLGSGEFGIIRKG-FLRSKNSKNEEKESRLEVAVKLPLNEYNQIQQELIYDELKVMCAV 237

  Fly   441 -KHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLR-------------SAGRETLDAVALLYMA 491
             ||||::.|:|..|......|::||:.:|:||.|||             ...:::|..|.||..|
 Worm   238 GKHPNILALVGGITFGERKMIVSEFVENGDLLSFLRDNRIYFTNDQWTLETEQDSLSLVDLLSFA 302

  Fly   492 TQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMRDDTY--TAHAGAKFPIKWTA 554
            .|||.||.||.....:|||||.||.|:..|:::::|||||||..::..|  |.......||.|.|
 Worm   303 FQIAKGMEYLIHVPCVHRDLALRNVLIKKNRIIRIADFGLARRHKNKDYYKTQSVDTPLPIHWMA 367

  Fly   555 PEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAI---DLTDVYHK-----LDKGYRMERPPGC 611
            ||.:....|:.|||||::||.|:|:.:.|.|||..:   |..|.|.|     |::|.|:.:|...
 Worm   368 PESIDKLLFTQKSDVWSYGVCLYELFSLGKSPYENVIKYDQRDFYWKYVLSYLNEGKRLAQPAHA 432

  Fly   612 PPEVYDLMRQCWQWDATDRPTFKSIHHALEHMFQESS------ITEAVEKQLN 658
            ..|:|::|:.||..|...|.||.......|...:.:|      :|..:..:.|
 Worm   433 DAEIYNVMKLCWDLDMNSRTTFLDCIEFFEKELKTTSNEYFLDLTRKLRSETN 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abl	NP_001261962.1	SH3_Abl	209..263	CDD:212784
		SH2_ABL	268..363	CDD:198189
		PTKc_Abl	382..644	CDD:270645	100/291 (34%)
		FABD	1584..1723	CDD:197885
old-1	NP_496130.2	PTKc	179..462	CDD:270623	97/283 (34%)