Protein Alignment Abl and svh-2

DIOPT Version :10

• Sequence 1: NP_001261962.1
• Gene: Abl / 45821
• FlyBaseID: FBgn0000017
• Length: 1723
• Species: Drosophila melanogaster
• Sequence 2: NP_509104.1
• Gene: svh-2 / 180929
• WormBaseID: WBGene00020504
• Length: 1086
• Species: Caenorhabditis elegans
• Alignment Length: 361
• Identity: 118/361 - (32%)
• Similarity: 184/361 - (50%)
• Gaps: 40/361 - (11%)

  Fly   376 SPEPD---EWEICRTDIMMKHKLGGGQYGEVYEAVW---KRYGNTVAVKTLKEDTMALKDFLEEA 434
            |..||   :::..|.|.:  ..:|.|.||.||:|::   |.....|..|.|||.  .:.:|.|||
 Worm   721 SMRPDLKVDFKNLRVDKL--DPIGQGHYGVVYKAMYSPSKSLEEKVVCKYLKEG--KISEFYEEA 781

  Fly   435 AIMKEMKHPNLVQLIGVCTREPPF--YIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASG 497
            ..|.|..|||:::||||...:...  .||||:|:.|:|..|:.:. ..|:....|...|..||.|
 Worm   782 RTMSEFDHPNILKLIGVALDDSSHLPIIITEYMAKGDLKSFIENV-ENTIKMRDLFEFAFDIAKG 845

  Fly   498 MSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMRDDT--YTAHAGAKFPIKWTAPEGLAY 560
            |:|:.|:.:||||||.||||:.::..||:|||||.|.:..:|  |........|::|..|| ::.
 Worm   846 MNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQMHERDLPVRWFPPE-ISE 909

  Fly   561 NKFSTKSDVWAFGVLLWEIATYGMSPYPAID---LTDVYHKLDKGYRMERPPGCPPEVY-DLMRQ 621
            ..|...||:|:|||::||:.|.|.:||..:.   |...:.|..:..|:.:||.||.::| |:|..
 Worm   910 QGFGITSDIWSFGVVIWELFTRGSTPYSNMASWILILPWLKESETNRLRKPPYCPEKLYTDVMLA 974

  Fly   622 CWQWDATDRPTFKS----IHHALEHM--FQESSITEAVEKQLNANATSAS----------SSAPS 670
            ||:.:..:||.|..    |.:.:::|  :..|.:....|: :::...|.|          :..|:
 Worm   975 CWKANPAERPQFSDLVTIIPNVVKYMEGYDRSQLQAGYER-VSSRFLSLSRHDPAFPIYQNEMPN 1038

  Fly   671 TSGVATGGGATT---TTAASGCASSSSATASLSLTP 703
            |..:|.....|.   |.|.....|.|::||....||
 Worm  1039 TPLLANCQNDTNDSKTLAELPSDSPSTSTAIPQSTP 1074

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abl	NP_001261962.1	SH3_Abl	209..263	CDD:212784
		SH2_ABL	268..363	CDD:198189
		PTKc_Abl	382..644	CDD:270645	99/278 (36%)
		FABD	1584..1723	CDD:197885
svh-2	NP_509104.1	TyrKc	735..993	CDD:197581	96/263 (37%)