Protein Alignment Abl and F57B9.8

DIOPT Version :10

• Sequence 1: NP_001261962.1
• Gene: Abl / 45821
• FlyBaseID: FBgn0000017
• Length: 1723
• Species: Drosophila melanogaster
• Sequence 2: NP_498511.1
• Gene: F57B9.8 / 175967
• WormBaseID: WBGene00018999
• Length: 444
• Species: Caenorhabditis elegans
• Alignment Length: 469
• Identity: 135/469 - (28%)
• Similarity: 224/469 - (47%)
• Gaps: 55/469 - (11%)

  Fly   267 LEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISL-----RYEGRVYHYRISEDPD 326
            :.:..::||.:.|...:.||..  ||.:|:|.||.....|.:.:     .....|.|| :....|
 Worm     3 INEQPFFHGLLPREEVKLLLQK--NGDYLMRTSEPQGQARHLIISVMQNETSQEVAHY-VIRTSD 64

  Fly   327 GKVFVTQEAKFNTLAELVHHHSVPHEGHGLITPLLYPAPKQNKPTVFPLSPEPDEWEICRTDIMM 391
            |...:|.:.||.||.|||:||........:.:.:|          |.|:..:  .||:...||.|
 Worm    65 GAYSITDKIKFGTLTELVNHHKQAKISEEVASSVL----------VNPIGRQ--SWELNHADITM 117

  Fly   392 KHKLGGGQYGEVYEAVWKRYGNT--VAVKTLKEDTMA---LKDFLEEAAIMKEMKHPNLVQLIGV 451
            ...||.|.:|||.....|....|  ||:|..|.:.:.   :|:.:.||.:|:...|.|:|:..||
 Worm   118 TKVLGEGAFGEVKLGTLKMGSTTVDVAIKVAKLEKVTKEQIKEIITEARLMRGFDHKNVVKCYGV 182

  Fly   452 CTREPPFYIITEFMSHGNLLDFLRSAGR----ETLDAVALLYMATQIASGMSYLESRNYIHRDLA 512
            ...:.|..::.|.:..|.|..:|:....    |.||.:|      |:|:|::|:.|:|.||||:|
 Worm   183 AAIDEPLLVVMELVPGGALDKYLQKNSSVQWPEKLDIIA------QVAAGLAYIHSKNIIHRDIA 241

  Fly   513 ARNCLVGDNKLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLW 577
            |||.|.|.. :.||:||||:|:..:  |......:.||:|.:||.:....::.::||:||.:|.|
 Worm   242 ARNILYGKG-VAKVSDFGLSRVGTE--YQMDPSKRVPIRWLSPETIVSFLYTPQTDVFAFSILCW 303

  Fly   578 EIATYGMSPYPAIDLTDVYHKLDK-GYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALE 641
            |:...|..|||.:.:..|:.|:.: .|||......|..:.|::::||..|...|||...:   ::
 Worm   304 EVIENGAQPYPEMLVVQVHQKVGRDDYRMPISQKAPAMLADVIKKCWIRDPQQRPTMSQV---VQ 365

  Fly   642 HMFQ------ESSITEAVEKQLNANATSAS-SSAPSTSGVATGGGATT----TTAASGCASSSS- 694
            .|::      ::|:.::. .||.|...|.. .|.|.....|...|...    ::|::|...:|.
 Worm   366 MMYEITGKKDKTSVNKST-GQLRAKMMSTGPMSDPMRDKTAKKTGRRNKKKPSSASNGPGGNSGP 429

  Fly   695 ATASLSLTPQMVKK 708
            ::..||.....:||
 Worm   430 SSGPLSGKDSRLKK 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abl	NP_001261962.1	SH3_Abl	209..263	CDD:212784
		SH2_ABL	268..363	CDD:198189	28/99 (28%)
		PTKc_Abl	382..644	CDD:270645	88/271 (32%)
		FABD	1584..1723	CDD:197885
F57B9.8	NP_498511.1	SH2_Fps_family	1..91	CDD:198224	27/90 (30%)
		STYKc	115..367	CDD:214568	85/263 (32%)